Sameh Obeid

ORCID: 0009-0007-3465-6090
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About
Contact & Profiles
Research Areas
  • Extracellular vesicles in disease
  • Proteins in Food Systems
  • Lipid Membrane Structure and Behavior
  • Nanopore and Nanochannel Transport Studies
  • Infant Nutrition and Health
  • Food Chemistry and Fat Analysis
  • Microfluidic and Bio-sensing Technologies
  • Microfluidic and Capillary Electrophoresis Applications
  • Force Microscopy Techniques and Applications
  • Innovative Microfluidic and Catalytic Techniques Innovation
  • Food Allergy and Anaphylaxis Research
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Immune cells in cancer
  • Research on Leishmaniasis Studies
  • Blood transfusion and management
  • Toxin Mechanisms and Immunotoxins
  • Electrowetting and Microfluidic Technologies
  • Blood properties and coagulation
  • Cellular Mechanics and Interactions
  • Advanced Fluorescence Microscopy Techniques
  • Polysaccharides Composition and Applications
  • Lattice Boltzmann Simulation Studies
  • Inflammatory Biomarkers in Disease Prognosis
  • Cellular transport and secretion
  • Lubricants and Their Additives

Centre National de la Recherche Scientifique
2015-2024

Université Paris-Saclay
2023-2024

Institut Galien Paris-Saclay
2023

Laboratoire des Biomolécules
2023

Laboratoire Science & technologie du Lait & de l'œuf
2018-2020

Université Bourgogne Franche-Comté
2018-2019

Franche-Comté Électronique Mécanique Thermique et Optique - Sciences et Technologies
2016-2019

Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2018

École Nationale Supérieure de Mécanique et des Microtechniques
2016

Université de technologie de belfort-montbéliard
2016

A method is presented for combining atomic force microscopy (AFM) mode and fluorescence in order to (a) mechanically stimulate immune cells while recording the subsequent activation under form of calcium pulses, (b) observe mechanical response a cell upon photoactivation small G protein, namely Rac. Using commercial set-ups robust signal coupling excitation light cantilever bending, applied signals were very easily synchronized. This approach allows control entire history single up its down...

10.1016/j.ultramic.2015.10.014 article EN cc-by-nc-nd Ultramicroscopy 2015-10-23

Extracellular vesicles (EVs) are membrane-derived, tiny produced by all cells that range from 50 to several hundreds of nanometers in diameter and used as a means intercellular communication. They emerging promising diagnostic therapeutic tools for variety diseases. There two main biogenesis processes produce EVs with differences size, composition, content. Due their high complexity cell origin, characterization requires combination analytical techniques. This project involves the...

10.3791/64210 article EN Journal of Visualized Experiments 2023-03-17

Antileishmanial chemotherapy is currently limited due to severe toxic side effects and drug resistance. Hence, new antileishmanial compounds based on alternative approaches, mainly avoid the emergence of resistance, are needed. The present work aims decipher mechanism action an candidate, named VP343, inhibiting intracellular Leishmania infantum survival via host cell. Cell imaging showed that VP343 interferes with fusion parasitophorous vacuoles cell late endosomes lysosomes, leading...

10.1016/j.isci.2023.108144 article EN cc-by iScience 2023-10-06

Extracellular vesicles (EVs) are membrane-derived, tiny produced by all cells that range from 50 to several hundreds of nanometers in diameter and used as a means intercellular communication. They emerging promising diagnostic therapeutic tools for variety diseases. There two main biogenesis processes produce EVs with differences size, composition, content. Due their high complexity cell origin, characterization requires combination analytical techniques. This project involves the...

10.3791/64210-v article EN 2023-03-18
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