Photodynamic therapy (PDT) and photothermal (PTT) possess different merits in cancer phototherapy, but the tumor microenvironment becomes unfavorable during phototheranostic progress. Herein, we report a self-adaptive cyanine derivative Cy5-TPA with PDT-dominated state to PTT-dominated autoswitch feature for enhanced photoimmunotherapy. The incorporation of rotatable triphenylamine (TPA) moiety renders temperature or intramolecular-motion regulated photoactivities, which shows preferable...

As the key of photodynamic therapy (PDT), current photosensitizer (PS) design highly relies on promoting intersystem crossing (ISC) process to form triplet excited state, thus generating toxic reactive oxygen species (ROS). However, ISC is a spin-forbidden with low state generation yield (<100%). Herein, as proof concept, we report new strategy aggregation induced singlet fission (SF) an ultrafast rate (<100 ps) and very high (>100%) efficient PSs. Such unique SF demonstrated anthracene...

Sonodynamic therapy (SDT) with largely improved penetration depth over photodynamic has shown promising performance in noninvasive tumor treatment but is limited by insufficient reactive oxygen species (ROS). We report a metal–organic framework (MOF) constructed from fluorgens aggregation-induced emission (AIEgens) that possesses the unique aggregation-enhanced ROS generation ability for SDT. The SDT's effect of this TPPE-Zn-MOF enhanced following reasons. First, TPPE coordinated Zn cluster...

Controllable carbon monoxide (CO) release simulated by light-generated reactive oxygen species (ROS) represents a promising approach for cancer therapy but is hampered low CO rate and ROS generation of conventional photosensitizers in hypoxia tumor microenvironments. In this study, we developed highly efficient nanoplatform (TPyNO

ABSTRACT Recently, the nanomedicine has been applied to reduce inflammation, heal mucosa, and slow down progression of illness. Silver nanoparticles are among useful metallic that have notable anti‐inflammatory properties. In present investigation, aqueous extract Trachyspermum copticum L was used green‐form silver nanoparticles. A variety methods, including Fourier transform infrared spectroscopy (FT‐IR), X‐ray diffraction (XRD), ultraviolet–visible (UV–Vis) spectroscopy, field emission...

Urbanization, industrialization, land development, and other human activities have led to ecological issues such as shrinking lake wetlands, fragmented cropland, reduced biodiversity. Taking the Poyang Lake urban agglomeration study area, textual analysis method was used analyze typical facts of historical succession since 1949, then index spatial were adopted characterize temporal evolution ecosystem health in period 2003–2020. On this basis, spillover effects on investigated based Durbin...

Heavy metal pollution mainly caused by human activities is becoming increasingly prominent and threatening health ecosystem safety in soil, which a non-renewable natural resource that humans rely on for survival development. Assessment analysis of soil heavy risk significant protecting health, preventing pollution, maintaining security. Based the investigation metals, including Cr, Pb, Cd, As, Hg, cultivated Liuhe District, assessment model was used to identify characteristics spatial...

J-aggregates show great promise in phototherapy, but are limited to specific molecular skeletons and poor self-assembly controllability. Herein, we report a twisted-planar strategy with sonication-induced J-aggregation develop donor-acceptor (D-A) type for phototherapy. With propeller aggregation-induced emission (AIE) moieties as the twisted subunits thiophene planar π-bridge, optimal π-interaction MTSIC induces appropriate slip angle formation, redshifting absorption from 624 nm 790 nm. In...

Single threshold could not achieve the effective segmentation of ship target and two-dimensional Otsu method has problem large computation cost. In order to improve efficiency segmentation, an algorithm combined QGA with image based on double was proposed. It takes as objective function seek by global optimization algorithm. This can obtain optimal threshold, running speed is improved nearly two times that genetic two-dimension Otsu.

The testing image have a certain degree of ambiguity when Application machine vision method for MEMS dynamic parameters were measured.This paper presents sub-pixel algorithm: Using self-similar characteristics fractal interpolation to overcome the problem ,that can not be accurate and edge reconstruction. Then because abilities high resolution anti-noise,after that using wavelet transform obtain detection.The experimental results show algorithm reach 0.02 pixel accuracy. DOI: ...

Invariant feature is desirable in image recognition and computer vision, while matching limited the distance or relative measurement between model. In this paper, we propose a novel method for based on polynomial curve fitting. Non-redundant complex moments are derived, that invariant to translation, constraint scale rotation, below 4th order selected as feature. With principle of fitting, similarity fitting coefficients non-redundant invariants calculated describe images. Finally it applied...

To obtain the MEMS micro structure's high resolution measurement dynamic parameters ,this paper ,by obtaining stroboscopic imaging technology of structure moving image sequence,  proposed one kind based on phase correlation technique and singular value decomposition combining sub-pixel method. By method correlation, space coordinate can transform into frequency domain to coordinates parameter space. And then through matrix, using least-squares fitting, get level displacement results. The...

Visible light imaging systems have a wide range of applications, including military, aerospace and biomedical applications. Among them, the detection capability evaluation an photoelectric system is important topic, when designed, there will be indicator to check whether qualified, its operating distance one acceptance indicators for system. When visible works at greater distance, people can find target further location, but same time, contrast on detector reduced, even may not detected. So...

The notorious tumor microenvironment (TME) usually becomes more deteriorative during phototherapeutic progress that hampers the antitumor efficacy. To overcome this issue, we herein report ameliorative and adaptive nanoparticles (TPASIC-PFH@PLGA NPs) simultaneously reverse hypoxia TME switch photoactivities from photothermal-dominated state to photodynamic-dominated maximize effect. TPASIC-PFH@PLGA NPs are designed by incorporating oxygen-rich liquid perfluorohexane (PFH) into intraparticle...

<title>Abstract</title> To determine the source apportionment and ecological risk of heavy metals in water from a spatiotemporal perspective, 7 samples were monitored 2020 to 2022 Taihu Lake. The correlation analysis principal component employed identify sources metals, temporal spatial characteristics analyzed using Mann-Kendall test, mean gravity center, standard-deviation ellipse. results indicated an increase median concentration following order: Cd &lt; Pb Hg Cu As Ni Zn, These...

Abstract J‐aggregates show great promise in phototherapy, but are limited to specific molecular skeletons and poor self‐assembly controllability. Herein, we report a twisted‐planar strategy with sonication‐induced J‐aggregation develop donor–acceptor (D–A) type for phototherapy. With propeller aggregation‐induced emission (AIE) moieties as the twisted subunits thiophene planar π‐bridge, optimal π‐interaction MTSIC induces appropriate slip angle formation, redshifting absorption from 624 nm...

Logbook is an important legal document for recording and analyzing navigation conditions, accumulating data, summarizing experience. The completeness accuracy of manual logbooks are largely determined by the navigational officer's proficiency status. Voyage Date Recorder records objective information, but its content doesn't contain any logic. In this paper, electronic logbook based on finite state machine proposed. By abstracting voyage into ship's initial a subsequent chain events, can...

At present, the State Grid Corporation of China vigorously promotes construction “Online Grid”, and has a variety emerging power businesses such as payment, electricity, energy services. In order to solve problem single authentication security risks in static closed identity management mechanism existing services, this paper proposes unified based on FIDO UAF protocol identity-based cryptography (IBC). The solution is change traditional “username+password” mode through protocol, use IBC...

Abstract Exploring effective logistics machinery and equipment fault diagnosis prediction technology to achieve efficient stable operation of equipment. In this paper, starting from the technology, we optimize hyperparameters recurrent gate unit neural network by using improved second-order oscillatory particle swarm algorithm then construct IPSO-GRU model. The model is used test effect hydraulic lift table hoist historical data as training data. accuracy was 6% compared with BP network....

To determine the source apportionment and ecological risk of heavy metals in water from a spatiotemporal perspective, 7 samples were monitored 2018 to 2020 Taihu Lake. The correlation analysis principal component employed identify sources metals, temporal spatial characteristics analyzed using Mann-Kendall test, mean gravity center, standard-deviation ellipse. results indicated an increase median concentration following order: Cd < Pb Hg Cu As Ni Zn, These primarily derived industrial...

In order to obtain the MEMS micro structure's high resolution measurement dynamic parameters ,this paper ,by obtaining stroboscopic imaging technology of structure moving image sequence, proposed one kind based on phase correlation technique and singular value decomposition combining sub-pixel method. By method correlation, space coordinate can transform into frequency domain coordinates parameter space. And then through matrix, using least-squares fitting, get level displacement results....

Application of machine vision method for MEMS dynamic parameters were measured, the testing image have a certain degree ambiguity.This paper presents sub-pixel algorithm based on fractal and wavelet transform: Firstly, using self-similar characteristics interpolation to overcome problem ,that can not be accurate edge reconstruction. Then because abilities high resolution anti-noise,using transform modulus maxima,the detection.The experimental results show that reach 0.02 pixel accuracy.