- Ovarian function and disorders
- Mitochondrial Function and Pathology
- Reproductive Biology and Fertility
- Acupuncture Treatment Research Studies
- Menstrual Health and Disorders
- Birth, Development, and Health
- Ultrasound and Hyperthermia Applications
- Infrared Thermography in Medicine
- Pluripotent Stem Cells Research
- Respiratory and Cough-Related Research
- Bacterial Identification and Susceptibility Testing
- Asthma and respiratory diseases
- Neonatal and Maternal Infections
- Thermoregulation and physiological responses
- Adipose Tissue and Metabolism
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Hypothalamic control of reproductive hormones
- Healthcare and Venom Research
- Streptococcal Infections and Treatments
- Adipokines, Inflammation, and Metabolic Diseases
- Genetics, Aging, and Longevity in Model Organisms
- Per- and polyfluoroalkyl substances research
Fudan University
2022-2025
State Key Laboratory of Medical Neurobiology
2024-2025
Zhongshan Hospital
2024-2025
China Association of Acupuncture-Moxibustion
2025
Shanghai Medical College of Fudan University
2024
Sanofi (United States)
2023
Linkou Chang Gung Memorial Hospital
2022
Chang Gung University
2022
Excessive gonadotropin-releasing hormone (GnRH) is considered to be an initiating factor in the etiology of polycystic ovary syndrome (PCOS). GnRH neuronal axons terminate at hypothalamic arcuate nucleus and median eminence, where tanycytes, specialized glial cells, have been proposed modulate secretion through plasticity. However, precise role “GnRH-tanycyte unit” during pathological state PCOS has not thoroughly explored. In this study, we demonstrated architecture distribution neurons...
Advanced-age women have a lower good-quality embryo rate (GQER) compared to young women. However, GQER varies widely within the same age group, suggesting that factors beyond influence quality. Mitochondria regulate cellular metabolism through dynamic fission and fusion alterations. Specifically, cumulus cell (CC) mitochondria not only of CCs but also adjacent oocytes. This study aims investigate relationship between CC mitochondrial dynamics oocyte developmental potential...
Low-frequency electroacupuncture (EA) has been shown to ameliorate obesity and reproductive dysfunctions in patients with polycystic ovary syndrome (PCOS), further explorations PCOS-like rats showed that EA could affect white adipose tissue. However, the function neuromodulation of brown tissue (BAT) PCOS after treatment have remained unknown. The present study focused on role BAT its relationship characterized three-dimensional (3D) innervation associated activation molecules.Female (21...
The identification of risk factors associated with uncontrolled moderate-to-severe asthma is important to improve outcomes. Aim this study was identify for in United States cohort using electronic health record (EHR)-derived data.In retrospective real-world study, de-identified data adolescent and adult patients (≥12 years old) asthma, based on medications within 12 months prior asthma-related visit (index date), were extracted from the Optum® Humedica EHR. baseline period index date....
Streptococcus agalactiae (group B [GBS]) is well known to cause serious diseases in infants. A serotype Ib GBS strain has recently emerged and become prevalent Southeast Asia. We aimed investigate the clinical genetic characteristics of this strain. All neonates with invasive from a tertiary-level medical center Taiwan between 2003 2020 were analyzed. The capsule serotyping, multilocus sequence typing, antimicrobial resistance analyses performed on all isolates, whole-genome sequencing (WGS)...
Objective: A biological system's internal morphological structure or function can be changed as a result of the mechanical effect focused ultrasound. Pulsed low-intensity ultrasound (LIFU) has effects that might induce follicle development with less damage to ovarian tissue. The potential LIFU non-invasive method for treatment female infertility is being considered, and this study sought explore confirm activate follicles. Results: We found 50% increase in weight number mature follicles on...
<title>Abstract</title> Background Advanced-age women have a lower good-quality embryo rate (GQER) compared to young women. However, GQER varies widely within the same age group, suggesting that factors beyond influence quality. Mitochondria regulate metabolism of their host cells through dynamic fission and fusion alterations. Specifically, cumulus cell (CC) mitochondria not only CCs but also adjacent oocytes. This study aims investigate relationship between CC mitochondrial dynamics oocyte...
Abstract Background: Low-frequency electroacupuncture (EA) has been shown to ameliorate obesity and reproductive dysfunctions in patients with polycystic ovary syndrome (PCOS), further explorations PCOS-like rats showed that EA could affect white adipose tissue (WAT). However, the function neuromodulation of brown (BAT) PCOS after treatment have remained unknown. The present study focused on role BAT its relationship EA, it characterized three-dimensional (3D) innervation associated...