Yuning Chen

ORCID: 0009-0007-4010-2756
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About
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Research Areas
  • Ovarian function and disorders
  • Mitochondrial Function and Pathology
  • Reproductive Biology and Fertility
  • Acupuncture Treatment Research Studies
  • Menstrual Health and Disorders
  • Birth, Development, and Health
  • Ultrasound and Hyperthermia Applications
  • Infrared Thermography in Medicine
  • Pluripotent Stem Cells Research
  • Respiratory and Cough-Related Research
  • Bacterial Identification and Susceptibility Testing
  • Asthma and respiratory diseases
  • Neonatal and Maternal Infections
  • Thermoregulation and physiological responses
  • Adipose Tissue and Metabolism
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Hypothalamic control of reproductive hormones
  • Healthcare and Venom Research
  • Streptococcal Infections and Treatments
  • Adipokines, Inflammation, and Metabolic Diseases
  • Genetics, Aging, and Longevity in Model Organisms
  • Per- and polyfluoroalkyl substances research

Fudan University
2022-2025

State Key Laboratory of Medical Neurobiology
2024-2025

Zhongshan Hospital
2024-2025

China Association of Acupuncture-Moxibustion
2025

Shanghai Medical College of Fudan University
2024

Sanofi (United States)
2023

Linkou Chang Gung Memorial Hospital
2022

Chang Gung University
2022

Excessive gonadotropin-releasing hormone (GnRH) is considered to be an initiating factor in the etiology of polycystic ovary syndrome (PCOS). GnRH neuronal axons terminate at hypothalamic arcuate nucleus and median eminence, where tanycytes, specialized glial cells, have been proposed modulate secretion through plasticity. However, precise role “GnRH-tanycyte unit” during pathological state PCOS has not thoroughly explored. In this study, we demonstrated architecture distribution neurons...

10.34133/research.0619 article EN cc-by Research 2025-01-01

Advanced-age women have a lower good-quality embryo rate (GQER) compared to young women. However, GQER varies widely within the same age group, suggesting that factors beyond influence quality. Mitochondria regulate cellular metabolism through dynamic fission and fusion alterations. Specifically, cumulus cell (CC) mitochondria not only of CCs but also adjacent oocytes. This study aims investigate relationship between CC mitochondrial dynamics oocyte developmental potential...

10.1007/s10815-025-03431-7 article EN cc-by-nc-nd Journal of Assisted Reproduction and Genetics 2025-03-17

Low-frequency electroacupuncture (EA) has been shown to ameliorate obesity and reproductive dysfunctions in patients with polycystic ovary syndrome (PCOS), further explorations PCOS-like rats showed that EA could affect white adipose tissue. However, the function neuromodulation of brown tissue (BAT) PCOS after treatment have remained unknown. The present study focused on role BAT its relationship characterized three-dimensional (3D) innervation associated activation molecules.Female (21...

10.1186/s13020-022-00603-w article EN cc-by Chinese Medicine 2022-04-18

The identification of risk factors associated with uncontrolled moderate-to-severe asthma is important to improve outcomes. Aim this study was identify for in United States cohort using electronic health record (EHR)-derived data.In retrospective real-world study, de-identified data adolescent and adult patients (≥12 years old) asthma, based on medications within 12 months prior asthma-related visit (index date), were extracted from the Optum® Humedica EHR. baseline period index date....

10.2147/jaa.s383817 article EN cc-by-nc Journal of Asthma and Allergy 2023-05-01

Streptococcus agalactiae (group B [GBS]) is well known to cause serious diseases in infants. A serotype Ib GBS strain has recently emerged and become prevalent Southeast Asia. We aimed investigate the clinical genetic characteristics of this strain. All neonates with invasive from a tertiary-level medical center Taiwan between 2003 2020 were analyzed. The capsule serotyping, multilocus sequence typing, antimicrobial resistance analyses performed on all isolates, whole-genome sequencing (WGS)...

10.1128/spectrum.03778-22 article EN cc-by Microbiology Spectrum 2022-12-08

Objective: A biological system's internal morphological structure or function can be changed as a result of the mechanical effect focused ultrasound. Pulsed low-intensity ultrasound (LIFU) has effects that might induce follicle development with less damage to ovarian tissue. The potential LIFU non-invasive method for treatment female infertility is being considered, and this study sought explore confirm activate follicles. Results: We found 50% increase in weight number mature follicles on...

10.1109/ojemb.2024.3391939 article EN cc-by-nc-nd IEEE Open Journal of Engineering in Medicine and Biology 2024-01-01

<title>Abstract</title> Background Advanced-age women have a lower good-quality embryo rate (GQER) compared to young women. However, GQER varies widely within the same age group, suggesting that factors beyond influence quality. Mitochondria regulate metabolism of their host cells through dynamic fission and fusion alterations. Specifically, cumulus cell (CC) mitochondria not only CCs but also adjacent oocytes. This study aims investigate relationship between CC mitochondrial dynamics oocyte...

10.21203/rs.3.rs-5298954/v1 preprint EN cc-by Research Square (Research Square) 2024-10-25

Abstract Background: Low-frequency electroacupuncture (EA) has been shown to ameliorate obesity and reproductive dysfunctions in patients with polycystic ovary syndrome (PCOS), further explorations PCOS-like rats showed that EA could affect white adipose tissue (WAT). However, the function neuromodulation of brown (BAT) PCOS after treatment have remained unknown. The present study focused on role BAT its relationship EA, it characterized three-dimensional (3D) innervation associated...

10.21203/rs.3.rs-1355777/v1 preprint EN cc-by Research Square (Research Square) 2022-03-03
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