A 6-year-old, intact female cat presented with sudden collapse. Clinical examinations indicated severe regenerative anemia and a large abdominal mass containing fluid. An exploratory laparotomy revealed cystic lesion at the cranial end of right uterine horn. Ovariohysterectomy was performed, made full recovery. The contained blood clot 102 mL blood. Histological examination confirmed that hemorrhagic located within fallopian tube. thickened uterus vasodilation histologically diagnosed as...

Clinicopathological features of mammary gland tumors (MGTs) in 101 dogs were evaluated retrospectively. The incidence histological malignancy 60 small- and 41 other-breed 25% 58.5%, respectively. In 82 epithelial MGTs, small-sized (< 3 cm) or non-invasive predominant small breeds. multivariate survival analysis, breed (p=0.048) lower stage tumor cell invasion (p=0.006) significantly associated with longer time. These results suggest that the biological MGTs is small-breed than others.

The efficacy of recombinant human bone morphogenetic protein-2 (rhBMP-2) combined with poly D, L lactic-co-glycolic acid (PLGA)/gelatin sponge complex (PGS) as a carrier on the repair segmental long-bone defects was evaluated using an ulnar model in dogs. defect 2 cm length and fixed plating. After implantation PGS or without rhBMP-2, process by serial radiography until 16 postoperative weeks. All treated 160 micrograms 640 rhBMP-2/PGS revealed union radiographically 12 weeks, whereas all...

We assessed the effects of cardiac re-synchronization therapy (CRT) in patients who developed otherwise unexplained heart failure (HF) during right ventricular apical (RVA)-pacing for acquired complete atrioventricular block (CAVB).Eighteen consecutive CAVB with HF RVA-pacing were haemodynamic studies immediately and 12 months after CRT-upgrade. Ten had idiopathic 13 showed normal left (LV) function at RVA-pacemaker implantation. 81 +/- 10 months. duration correlated (r = 0.49, P < 0.05) LV...

We evaluated the postsurgical outcomes of cutaneous or subcutaneous mast cell tumors (MCTs, n=25) in 23 dogs, resected with lateral surgical margins proportional to widest tumor diameter, including at least one facial plane. The diameter range was 0.3–2.6 cm (median: 0.9 cm), and all were histologically diagnosed as Kiupel's low-grade MCT. Resection complete 20, close (deep margin) three, incomplete two. No dogs developed local recurrence site initial surgery during follow-up 161–2,219 days...

A cutaneous mass at the base of retroauricular region a 4-year-old, female Golden Retriever was examined pathologically. Histologically, formed multiple nodules consisting proliferation large clear cells with abundant cytoplasm. Mitotic figures among neoplastic were very sparse. The intensely positive for cytokeratins (AE1/AE4, cytokeratin 8 and 18) moderately lysozyme contained periodic acid-Schiff-positive granules in In addition, small flat lined islands cells, these strongly alpha-smooth...

A 7-year-old spayed female Pomeranian with a 6-month history of progressive paraparesis was determined to have syringomyelia accompanied hydrocephalus. Magnetic resonance imaging clearly revealed severe in the cervical portion spinal cord, which directly connected marked dilated fourth ventricle. Acetazolamide prescribed for 3 weeks, but neurologic deficits progressed. Laminectomy first and second vertebrae, is one method treating this type human beings, performed, then, acetazolamide...

A large subcutaneous mass at the left cervical site in a 9-year-old male Siberian husky was removed surgically. Histopathologically, mainly consisted of proliferation spindle-shaped neoplastic cells arranging solid sheath and partially vascular channels containing few blood cells. The tumor exhibited highly invasive activity to surrounding tissues. In addition, were immunopositive for Factor VIII-related antigen. On basis these findings, diagnosed as lymphangiosarcoma. Recurrent noticed 3...

A 5-year-old female border collie presented with erythematous skin lesions at the axillae, groin, mucocutaneous junctions, and pinnae. Biopsy revealed lymphocytic interface dermatitis hydropic degeneration of basal cells keratinocyte apoptosis. Based on gross histological features, diagnosis erythema multiforme was made. The disease resolved by treatment azathioprine, prednisolone, a hypoallergenic diet. Finally, lesion controlled without drug therapy but recurred easily every time...

A 4-year-old female French bulldog presented with a 6-month history of right-sided head tilt and acute onset ataxia. Magnetic resonance imaging (MRI) showed large mass lesion at the cerebellomedullary pontine angle. The dog was able to stand walk after beginning symptomatic therapy prednisolone, acetazolamide glycerin. 10 months first examination indicated slight expansion tumor. continuous for 15 until death, although persisted. On postmortem examination, gross tumor slightly larger than...

This is the first report on successful treatment of spontaneous nonunion fracture a dog by use recombinant human bone morphogenetic protein-2 (rhBMP-2). A 4-year-old Pomeranian with 2-year history femoral was treated implantation rhBMP-2. The had received surgical correction twice prior to admission but radiography affected limb revealed typical figure fracture. Glossly, fractured ends were sclerotic and area between filled fibrous tissue. After debridement shaft fixed an 8-hole plate....

A 14-year-old spayed female cat weighing 2.3 kg developed tension pneumoperitoneum that progressed for 6 hr. Abdominocentesis was performed and 1.3 L of gas aspirated after which the cat's respiratory condition improved. The next day, abdomen redistended, laparotomy performed. gastric perforation noted sutured margin resection. showed a good physical without any gastrointestinal signs at months surgery.

An 11-year-old male Golden Retriever presented with progressive weight loss, tachycardia, hyperthermia, polyuria and polydipsia. A freely movable mass, 4.5 × 4 cm in size, was palpated at the cranioventral cervical region. Hormonal study revealed high levels of serum thyroid hormones, a tentative diagnosis hyperthyroidism due to tumor made. The removed surgically diagnosed histopathologically as gland adenoma. Serum hormone decreased after surgery improved clinical signs. At 12 months...

ABSTRACT Several factors are suggested to be involved in the development of nontraumatic inguinal hernias (NTIHs) dogs, but case series studies focusing on etiology and treatment outcomes limited. The aim this study was retrospectively evaluate clinical characteristics NTIHs dogs. Medical records 42 dogs with surgically treated were reviewed. Forty-one included study, all small breeds weighing &amp;lt;10 kg, middle older age (&amp;gt;5 yr old; 33 cases), female sex (34 miniature dachshunds...

Surgery and platinum-based chemotherapy are highly efficacious for treating advanced ovarian cancers in humans, but their efficacy is less known dogs. We evaluated the long-term treatment outcomes of seven dogs with malignant tumors abdominal effusion. Ovariohysterectomies (OVHs) were performed on all dogs; four had adenocarcinoma (AC) gross dissemination peritoneum (two pleural effusion), three a granulosa cell tumor (GCT) no peritoneal cavity, although one showed Effusion resolved after...

犬49頭に発生した耳血腫59例を再検討した。体重5 kg以下、5~10 kg、10~20 kg、および20 kg以上の頭数はそれぞれ1(2.1%)、6(12.8%)、11(23.4%)、および29(61.7%)頭であった。ゴ-ルデンレトリバ-とラブラドールレトリバーで全発症犬の55.1%を占め、これらの犬種の高いリスクが示唆された。全59例の45例(76.3%)は外耳炎を併発しており、52例(88.1%)は5歳以上で発症していた。罹患耳を病理組織学的に検査した4例では耳介軟骨の糜爛が認められた。これらの結果から、耳血腫発症には大型犬(ゴールデンレトリバーおよびラブラドールレトリバー)、中高齢、および共存する外耳炎など複数の危険因子が存在し、さらに自己損傷や耳介軟骨の加齢性変化が、軟骨骨折の発生と続発する血腫形成に寄与していることが示唆された。

White-coat hypertension has been diagnosed arbitrarily based on different criteria. In 1997, the Joint National Committee-VI (JNC-VI) reported a new classification of and strongly emphasized importance ambulatory blood pressure (ABP) monitoring. The report pronounced normal ABP values for first time.The study's aim was to clarify relationship between casual (BP) patients with essential in each stage JNC-VI classification, prevalence white-coat by using criteria.Ambulatory monitored...

10歳、雌のシーズーに重度の胸腹水が認められた。試験開腹で両側性の卵巣腫瘤を認め、卵巣子宮摘出術を実施した。病理組織学的には、腹膜転移をともなう卵巣の乳頭状腺癌と診断された。手術後に胸水と腹水は消失したが、9ヵ月後に再発し、腹膜と胸膜の病理組織検査で腫瘍の再発が認められた。シスプラチンの体腔内化学療法によって胸水と腹水は4ヵ月間消失したが、その後は治療に反応せず疾患が進行し、初回手術の23ヵ月後に死亡した。

犬のアポクリン汗腺癌5症例の臨床および病理学的特徴を検討した。いずれも12歳以上の高齢犬に発生した単発腫瘍で、腫瘍細胞の表皮浸潤による潰瘍をともなっていた。全例で腺様構造、線維増生、間質浸潤がみられ、2例では硬癌の組織学的特徴も認められた。全例とも拡大切除によって局所制御はできたが、硬癌の特徴がみられた1例(前肢の指間腫瘍)は術後3ヶ月目に浅頸リンパ節転移が認められた。硬癌の別の1例(肘の固着腫瘍)には脈管浸潤があり、術後6ヶ月目に皮膚の転移巣が広がって死亡した。もっとも分裂指数が高かった1例(陰部横の腫瘍)は術後7ヶ月目に多臓器転移で死亡し、残りの2例は追跡中に転移は認められなかった。犬のアポクリン汗腺癌では拡大切除が局所制御に有効であるが、組織学的に硬癌の浸潤像、高分裂指数、脈管浸潤がみられる例では転移する可能性を考慮すべきと思われた。

An 8-month-old female cat presented with a 1-month history of open-mouth breathing and intermittent regurgitation. Contrast radiography revealed megaesophagus (ME) large pharyngeal mass. The mass was removed by gentle traction under general anesthesia, after which the ME resolved within 9 days. diagnosed as nasopharyngeal polyp based on clinical histopathological findings. A similar recurred 50 days postoperatively, also followed four treatments methylprednisolone acetate. remained...