A5082060745- Spine and Intervertebral Disc Pathology
- Nanoplatforms for cancer theranostics
- Cervical and Thoracic Myelopathy
- Inhalation and Respiratory Drug Delivery
- RNA Interference and Gene Delivery
- Diagnosis and Treatment of Venous Diseases
- Venous Thromboembolism Diagnosis and Management
- Autophagy in Disease and Therapy
- Hip and Femur Fractures
- Cardiac, Anesthesia and Surgical Outcomes
- Bone fractures and treatments
- Heme Oxygenase-1 and Carbon Monoxide
- Immunotherapy and Immune Responses
- Peripheral Artery Disease Management
- Extracellular vesicles in disease
- Phagocytosis and Immune Regulation
- Orthopaedic implants and arthroplasty
- Global Health Care Issues
- Medical Imaging and Analysis
- Spinal Fractures and Fixation Techniques
- Musculoskeletal pain and rehabilitation
Soochow University
2016-2025
First Affiliated Hospital of Soochow University
2016-2025
Dazhou Central Hospital
2024
Shantou University
2024
Osteosarcoma (OS) patients have a poor prognosis due to its high degree of heterogeneity and rate metastasis. Magnetic hyperthermia therapy (MHT) combined with immunotherapy is an effective strategy treat solid metastatic tumors. Here, we biodegradable magnesium (Mg) macroscale rods, which acted as eddy thermo-magnetic agent under low external alternating magnetic field, achieve radical cure for OS. The thermal effect (ETE) the Mg rods (MgR) showed outstanding cytotoxic effects enhanced...
Osteosarcoma (OS), a highly aggressive bone tumor, presents significant challenges in terms of effective treatment. We identified that cellular autophagy was impaired within OS by comparing clinical samples through bioinformatic analyses and further validated the inhibition mitochondrial at transcriptomic level. Based on this finding, we investigated therapeutic potential dual functional metal nanoplatform (MnSx) to facilitate transition from protective effect low-level killing high-level...
Spinal cord ischemia is largely caused by cervical spondylotic myelopathy (CSM), which has a corresponding biomechanical basis. Finite element analysis of spinal stress in diseased segments CSM was performed to provide basis for the pathogenesis CSM.A single segment (C4-5) patient with selected mechanical simulation three-dimensional (3D) computed tomography scanning, and 3D finite model vertebra constructed. Based on patient's age, sex, height, weight, other parameters, an individual...
At present, posterior interbody fusion surgery with pedicle internal fixation is the gold standard for treatment of lumbar degenerative disc diseases. However, an increasing number studies have shown that because fused vertebrae lose their physiological activity, compensatory range motion (ROM) adjacent levels increases. To address this issue, dynamic systems been developed.Our goal was to investigate short-term therapeutic efficacy Isobar TTL system diseases and its effect on ROM surgical...
Background: There is a lack of health economics studies on the treatment acute lower extremity deep venous thrombosis to measure benefits patients. The purpose this study was evaluate cost-effectiveness anticoagulation (AC), percutaneous mechanical thrombectomy (PMT), and catheter-directed thrombolysis (CDT). Methods: above 3 methods were selected according patient’s wishes. Related complications, clinical effective, occurrence post-thrombotic syndrome (PTS) after 2 years, total...
The world is experiencing a shift in population distribution toward older ages, known as aging. Globally, there were 703 million persons aged 65 or over 2019.[1][1] This figure will be doubled, accounting for 1.5 billion of the world’s by 2050.[1][1] While aging started
Background: Intramedullary fixation is the preferred treatment for AO type 31A2.2-3.3 intertrochanteric fractures. However, planting position of spiral blade into femoral head controversial, and relative biomechanical studies are sparse. This article aims to investigate influence different on fracture. Methods: A three-dimensional (3D) finite element model a fracture with proximal nail antirotation (PFNA) was developed in which collum femoris divided three parts based length blades....
Background Our study is to determine the correlation between preoperative MRI parameters of spinal cord compression and effects anterior surgery in patients with degenerative cervical myelopathy (DCM). Methods 24 normal subjects no evident abnormalities were selected as group A. 79 DCM underwent single-segment (C4–5/C5–6) ACDF formed operation group, separated into B (without high signal) C (with according absence or presence signal on T2-weighted respectively. (MCC, maximum canal...