Leandra Schaub

ORCID: 0009-0007-5140-6720
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About
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Research Areas
  • Bone Tissue Engineering Materials
  • Muscle Physiology and Disorders
  • Tissue Engineering and Regenerative Medicine
  • Temporomandibular Joint Disorders
  • 3D Printing in Biomedical Research
  • Bone Metabolism and Diseases
  • Oropharyngeal Anatomy and Pathologies
  • Dental Implant Techniques and Outcomes
  • Bone health and treatments
  • Orthopaedic implants and arthroplasty
  • HIV/AIDS oral health manifestations
  • Bone and Dental Protein Studies
  • TGF-β signaling in diseases
  • Dental Health and Care Utilization
  • Oral microbiology and periodontitis research

University of Geneva
2019-2024

To evaluate the knowledge and practices of Swiss women regarding oral health during pregnancy.Self-reported questionnaires were attributed to 385 from 4 public hospitals in French speaking part Switzerland February 2015 June 2016.The questionnaire consisted 32 questions including demographic characteristics, habits awareness changes pregnancy.The majority (64%) 3rd trimester pregnancy had a university education (41%). Oral was considered very important for half (52%) moderately 38% them. 71%...

10.3290/j.ohpd.b2573007 article EN PubMed 2022-01-20

Abstract Background Skeletal craniofacial morphology can be influenced by changes in masticatory muscle function, which may also change the functional profile of muscles. Objectives To investigate effects age and demands on expression Myosin Heavy‐Chain (MyHC) isoforms representative jaw‐closing jaw‐opening muscles, namely masseter digastric muscles respectively. Methods Eighty‐four male Wistar rats were divided into four groups, an immature ( n = 12; 4‐week‐old), early adult 24;...

10.1111/joor.13676 article EN cc-by Journal of Oral Rehabilitation 2024-03-12

Different demands on the muscles of mastication may influence their functional profile (size and distribution muscle fibre types), which change during growth maturation, potentially influencing craniofacial growth. The aim this study was to evaluate mRNA expression cross-sectional area masticatory fibres compared with limb in young adult rats. Twenty-four rats were sacrificed at two different ages, namely 12 4 weeks (young) 26 (adult). masseter, digastric, gastrocnemius soleus dissected....

10.3390/biology12060842 article EN cc-by Biology 2023-06-09

The basic principle of the rabbit calvarial model is to grow new bone tissue vertically on top cortical part skull. This allows assessment substitution materials for oral and craniofacial regeneration in terms growth neovascularization support. Once animals are anesthetized ventilated (endotracheal intubation), four cylinders made polyether ether ketone (PEEK) screwed onto skull, both sides median coronal sutures. Five intramedullary holes drilled within area delimited by each cylinder,...

10.3791/59976 article EN Journal of Visualized Experiments 2019-08-13

Deproteinized bovine bone mineral particles embedded in collagen (DBBM-C) are widely used for regenerations with excellent, albeit sometimes variable clinical outcomes. Clinicians usually prepare DBBM-C by mixing blood. Replacing blood saline represents an alternative. We investigated if treatment could improve i. handling vitro and ii. biological performances a rabbit calvarial model. In vitro, blocks soaked or were submitted to compression tests. vivo, four poly ether ketone...

10.3390/biomedicines9030308 article EN cc-by Biomedicines 2021-03-17

The basic principle of the rabbit calvarial model is to grow new bone tissue vertically on top cortical part skull. This allows assessment substitution materials for oral and craniofacial regeneration in terms growth neovascularization support. Once animals are anesthetized ventilated (endotracheal intubation), four cylinders made polyether ether ketone (PEEK) screwed onto skull, both sides median coronal sutures. Five intramedullary holes drilled within area delimited by each cylinder,...

10.3791/59976-v article EN Journal of Visualized Experiments 2019-08-13

Background Endothelial cells (EC) are specialized with respect to a function and local microenvironment. Recently, type-H EC (H-EC) were identified as the preferential interlocutor of osteoprogenitors (OP)- H-EC promote osteogenesis in return, OP angiogenesis. A clear correlation also exists between concentration presence H-EC. To date, nothing is known about influence bone substitute grafting on recruitment form these particular osteogenic niches. Aim/Hypothesis During regeneration process,...

10.1111/clr.73_13509 article EN Clinical Oral Implants Research 2019-09-01
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