- Bone Tissue Engineering Materials
- Dental Implant Techniques and Outcomes
- Dental materials and restorations
- Orthopaedic implants and arthroplasty
- 3D Printing in Biomedical Research
- Tissue Engineering and Regenerative Medicine
- Electrospun Nanofibers in Biomedical Applications
- Dental Radiography and Imaging
- Bone health and treatments
- Voice and Speech Disorders
- Dysphagia Assessment and Management
- Metal and Thin Film Mechanics
- Obstructive Sleep Apnea Research
- Additive Manufacturing and 3D Printing Technologies
- Dental Erosion and Treatment
- Reconstructive Surgery and Microvascular Techniques
- Endodontics and Root Canal Treatments
- Dental Trauma and Treatments
- Osteoarthritis Treatment and Mechanisms
- Bone Metabolism and Diseases
- Titanium Alloys Microstructure and Properties
- Coronary Interventions and Diagnostics
University of Geneva
2010-2022
University of Dental Medicine
2022
University of Zurich
2022
Hôpital Beau-Séjour
2019
This study evaluated the biocompatibility, mechanical properties, and surface roughness of CAD-CAM milled rapidly-prototyped/3D-printed resins used for manufacturing complete dentures. Six groups resin specimens were prepared, milled-base (MB), milled-tooth shade (MT), printed-tooth (PT), printed-base with manufacturer-recommended 3D-printer (PB1), third-party (PB2), in a vertical orientation (PB2V). Human epithelial (A-431) gingival (HGF-1) cells cultured tested biocompatibility using...
Oral soft tissue defects are a frequently encountered problem in dental praxis. Tooth loss, tooth root or implant recessions, infections trauma require reconstruction. The autologous graft remains the gold standard for gingiva and oral mucosa augmentation. However, prolonged pain, limited amount of harvested tissue, increased risk infection have prompted search off-shelf alternatives. Several acellularized dermal matrices been studied without satisfactory results. A newly developed...
Titanium is widely used in contemporary endosseous implantology and there considerable thrust to further promote osseointegration by implant surface modifications. The aim of this study was evaluate the effect a titanium-nitride-oxide (TiNOx) coating on commercially pure microroughened titanium assessing proliferation differentiation human primary osteoblasts.Cell proliferation, gene expression, alkaline phosphatase activity, osteoprotegerin osteocalcin secretion were analyzed for time...
This in vitro study evaluated technical outcomes of monolithic zirconia implant-supported fixed dental prostheses (iFDPs) supported by different designs titanium base abutments after aging and static load testing.Sixty three-unit (yttrium oxide partially stabilized tetragonal polycrystals; Y-TZP)iFDPs were produced divided into four groups: group A-conical for the prosthesis; B-cylindrical crown; C-conical abutment prosthesis cylindrical D-cylindrical prosthesis. The samples subjected to an...
Objectives: The aim of this study was to evaluate the effect different enamel surface treatments on micro-shear bond strength. Materials and methods: Sixty-four approximal surfaces from freshly extracted molars were randomly assigned eight groups, according combinations following treatments: ground or unground, 37.5% phosphoric acid etching time 15 30 s, with without primer application. same bonding agent (Optibond FL™ Adhesive, Kerr) then used for all a 1.8 mm diameter resin composite...
Abstract Objectives This study tested the hypothesis that modifying sequence of sodium hypochlorite (NaOCl)/ethylene diamine tetra-acetic acid (EDTA) irrigation during root canal shaping would improve apical cleanliness in moderately curved canals. Materials and Methods Forty-five canals were prepared using Protaper Gold with three protocols. Standard (SI) used 0.5 mL 3% NaOCl between each instrument, followed by 5 17% EDTA manually agitated for 30 seconds. Reverse (RI) then NaOCl, plus...
The basic principle of the rabbit calvarial model is to grow new bone tissue vertically on top cortical part skull. This allows assessment substitution materials for oral and craniofacial regeneration in terms growth neovascularization support. Once animals are anesthetized ventilated (endotracheal intubation), four cylinders made polyether ether ketone (PEEK) screwed onto skull, both sides median coronal sutures. Five intramedullary holes drilled within area delimited by each cylinder,...
Reduced tongue pressure may render eating and swallowing difficult. The purpose of this study was to investigate whether the training device can also be used as a diagnostic its sensitivity specificity are equal numerical measuring device.The target group is patients aged 70 years over who hospitalised for rehabilitation. Tongue measured by both, instrument tool. diagnosis reduced made with set verified novel tool.Sixty-two participants were included in study. Forty-five classified 53 'low...
Deproteinized bovine bone mineral particles embedded in collagen (DBBM-C) are widely used for regenerations with excellent, albeit sometimes variable clinical outcomes. Clinicians usually prepare DBBM-C by mixing blood. Replacing blood saline represents an alternative. We investigated if treatment could improve i. handling vitro and ii. biological performances a rabbit calvarial model. In vitro, blocks soaked or were submitted to compression tests. vivo, four poly ether ketone...
The object of the study was to fill and coat microcavities a drug eluting stent using batch dipping process. 316L coronary stents, which were coated with 0.25 μm layer TiNOx used as substrates. stents’ surface dimpled 0.21 μl separated by distances 17–28 depending on location. experiment consisted (1) optimizing procedures solution therapeutic agent (2) covering filled protective “lid” that shielded during insertion in arteries then controlled its release into surrounding tissue. filling...
Angiogenesis and bone regeneration are closely interconnected processes. Whereas type-H blood vessels abundantly found in the osteogenic zones during endochondral long development, their presence flat bones' development involving intramembranous mechanisms remains unclear. Here, we hypothesized that type-H-like capillaries highly express CD31 Endomucin (EMCN), may be present at sites of participate control osteogenesis. A rabbit model calvarial augmentation was used which growth controlled...
The basic principle of the rabbit calvarial model is to grow new bone tissue vertically on top cortical part skull. This allows assessment substitution materials for oral and craniofacial regeneration in terms growth neovascularization support. Once animals are anesthetized ventilated (endotracheal intubation), four cylinders made polyether ether ketone (PEEK) screwed onto skull, both sides median coronal sutures. Five intramedullary holes drilled within area delimited by each cylinder,...
Background The use of titanium bases (Ti-bases) as an implant abutment is a popular option part digital workflow. Notwithstanding all advantages this concept, its success highly dependent on the bonding stability and retention between Ti-base ceramic component. Several air-abrasion methods have been proposed for surface. Moreover, different cementation systems are available. However, it still not clear which best protocol to apply in clinical scenario. Aim/Hypothesis To select all-ceramic...
Background A primordial consideration in the development of implant surfaces is to promote not only bone integration but also soft tissue integration. The interface created between transgingival neck and mucosa a structured barrier oral environment periimplant bone. effectiveness this biological seal relies on several cell types, among these gingival keratinocytes fibroblasts. These types behave differently toward various materials surface characteristics. Aim/Hypothesis Soft attachment may...