A5100460298- Catalytic C–H Functionalization Methods
- Oxidative Organic Chemistry Reactions
- Synthesis and Catalytic Reactions
- Radical Photochemical Reactions
- Advanced Photonic Communication Systems
- Optical Network Technologies
- Sulfur-Based Synthesis Techniques
- Catalytic Cross-Coupling Reactions
- Biochemical and Structural Characterization
- Natural Language Processing Techniques
- Antimicrobial Peptides and Activities
- DNA and Biological Computing
- Semiconductor Lasers and Optical Devices
- Advanced Optical Network Technologies
- Advanced Authentication Protocols Security
- Venomous Animal Envenomation and Studies
Soochow University
2010-2024
Jiangsu Institute of Parasitic Diseases
2014
A new tert-butyl peresters synthesis directly from aldehydes and TBHP was developed viaBu4NI-catalyzed aldehyde C−H oxidation. Mechanistic studies suggest that the protocol proceeds via a radical process. Combining method with Kharasch–Sosnovsky reaction offers practical approach for of allylic esters simple alkenesvia two-step one-pot procedure.
A metal-free oxidative coupling of methyl ketones and primary or secondary amines to α-ketoamides has been developed. Four intermediates, α-iodoketone, α-aminoketone, iminium intermediate, α-hydroxy amine have identified through a series control experiments. The atom-economic methodology can be scaled-up, tolerates variety functional groups, is operationally simple.
A Ru-catalyzed oxidative coupling of arenes with boronic acids using molecular oxygen via direct C-H activation is reported. Both the scope and mechanism process are discussed.
Abstract A new reactivity pattern of α‐aminoalkyl radicals, involving nucleophilic attack on CN triple bonds under thermal conditions, has been developed to construct α‐amino nitriles. In contrast previous CH functionalization tertiary amines this methodology does not require the use photocatalytic conditions or a transition‐metal catalyst. Inexpensive and nontoxic phenylacetonitrile was chosen as cyano source for α‐aminonitrile forming reaction. plausible mechanism is proposed based upon...
Scorpine, a small cationic peptide from the venom of Pandinus imperator, which has been shown to have anti-bacterial and anti-plasmodial activities, potential important applications in pharmaceutical industries. However, isolation scorpine natural sources is inefficient time-consuming. Here, we first report expression purification recombinant Escherichia coli, using ubiquitin-related modifier (SUMO) fusion partner. The protein was expressed soluble form E. verified by SDS-PAGE western...
Verifying the correctness of outsourcing computation is both cumbersome and expensive, it also requires third-party verification if auditing or arbitrating involved. Due to its complexities, users are likely re-outsource workload trusted vendors. Multiple tasks increase expense communications expose more vulnerabilities. To address this problem, we propose an identity-based strong designated verifier dual signature scheme with constrained-delegatability. The particular innovation lies in two...
Abstract In contrast to established C‐H functionalizations of tertiary amines involving α‐aminoalkyl radicals the present method does not require photocatalytic conditions or a transition‐metal catalyst.An radical and benzoyl cyanide are key intermediates in this process.
Emerging correlated multi-symbol modulation (CMSM) techniques require sequence detection to effectively increase spectral efficiency. A simplified algorithm with low implementation complexity is proposed for CMSM-enhanced high-speed optical fiber transmissions. ©2023 The Author(s)
Abstract A simple, mild, and widely applicable method to prepare α‐ketoamides is reported.