A5100344619- Dam Engineering and Safety
- Simulation and Modeling Applications
- Optical Network Technologies
- Grouting, Rheology, and Soil Mechanics
- Advanced Photonic Communication Systems
- Thermochemical Biomass Conversion Processes
- Advanced Optical Network Technologies
- Flood Risk Assessment and Management
- Infrastructure Maintenance and Monitoring
- Industrial Technology and Control Systems
- Nanoplatforms for cancer theranostics
- Electrospun Nanofibers in Biomedical Applications
- Advancements in Battery Materials
- Manufacturing Process and Optimization
- Hydraulic flow and structures
- Nanoparticle-Based Drug Delivery
- Electromagnetic wave absorption materials
- Coal Properties and Utilization
- Environmental and Agricultural Sciences
- Pancreatitis Pathology and Treatment
- Advanced Algorithms and Applications
- Evaluation Methods in Various Fields
- Gastric Cancer Management and Outcomes
- Advanced Computational Techniques and Applications
- Advanced Sensor and Control Systems
Zhengzhou University
2008-2025
Beijing Children’s Hospital
2010-2025
Capital Medical University
2010-2025
Sichuan University
2015-2025
Henan Provincial People's Hospital
2024-2025
Huizhou University
2025
Jiangsu Vocational Institute of Architectural Technology
2025
Rice Research Institute
2022-2024
Jiangxi Academy of Agricultural Sciences
2022-2024
Central South University of Forestry and Technology
2004-2024
Using next-generation sequencing technology alone, we have successfully generated and assembled a draft sequence of the giant panda genome. The contigs (2.25 gigabases (Gb)) cover approximately 94% whole genome, remaining gaps (0.05 Gb) seem to contain carnivore-specific repeats tandem repeats. Comparisons with dog human showed that genome has lower divergence rate. assessment genes potentially underlying some its unique traits indicated bamboo diet might be more dependent on gut microbiome...
Abstract Antidiabetic medication may modulate the gut microbiota and thereby alter plasma faecal bile acid (BA) composition, which improve metabolic health. Here we show that treatment with Acarbose, but not Glipizide, increases ratio between primary BAs secondary levels of unconjugated in treatment-naive type 2 diabetes (T2D) patients, beneficially affect metabolism. Acarbose relative abundances Lactobacillus Bifidobacterium depletes Bacteroides , changing abundance microbial genes involved...
Engineering multifunctional nanocarriers for targeted drug delivery shows promising potentials to revolutionize the cancer chemotherapy. Simple methods optimize physicochemical characteristics and surface composition of need be developed in order tackle major challenges smooth translation suitable clinical applications. Here, rational development utilization mesoporous silica nanoparticles (MSNPs) targeting MDA‐MB‐231 xenograft model breast vivo are reported. Uniform redispersible...
Semiconductor photocatalytic reduction is a relatively new technique for the removal of dissolved toxic metal ions from wastewater. In this paper, adsorption and Cr(VI) to Cr(III) inaqueous solutions by UV/TiO2 photocatalysis has been investigated. It observed that pH solution plays an important role in reaction. An acidic medium favorable reduction, where 94% was photoreduced within 1 h at 3 when 2 g/L TiO2 used as slurry. study shows mainly occurs on surface TiO2. The presence Fe(III)...
Controllable magnetic Ag@Ni core–shell nanoparticles (NPs) have been designed and constructed on the bayberry tannin (BT) grafted skin collagen fiber (SCF) though a simple one-step route. Due to mild naturally occurring reduction ability of BT, when SCF-BT made contact with mixture Ag+/Ni2+ solution, BT was able preferentially reduce Ag+ into Ag NPs, subsequently, formed NPs served as in situ seeds for over growth Ni shell by NaBH4. The systematic TEM EDS analysis confirmed that as-prepared...
Abstract Biopharmaceuticals have emerged to play a vital role in disease treatment and shown promise the rapidly expanding pharmaceutical market due their high specificity potency. However, delivery of these biologics is hindered by various physiological barriers, owing primarily poor cell membrane permeability, low stability, increased size biologic agents. Since many biological drugs are intended function interacting with intracellular targets, targets relevance. In this review, authors...
Caffeic acid phenethyl ester (CAPE) could ameliorate myocardial ischemia/reperfusion injury (MIRI) by various mechanisms, but there hadn't been any reports on that CAPE regulate silent information regulator 1 (SIRT1) and endothelial nitric oxide synthase (eNOS) to exert cardioprotective effect. The present study aimed investigate the potential of caffeic o-nitro (CAPE-oNO2) MIRI possible mechanism based positive control CAPE. SD rats were subjected left coronary artery ischemia /reperfusion...
Abstract KLF4/GLKF4 is a transcription factor that can have divergent functions in different malignancies. The role of KLF4 prostate cancer etiology remains unclear. We recently reported small double-stranded RNA induce gene expression by targeting promoter sequence phenomenon referred to as activation (RNAa). In this study, we examine levels tissue and utilize RNAa tool for overexpression investigate its function. Expression analysis indicated significantly downregulated cell lines compared...
Impaired wound healing is a major source of morbidity in diabetic patients. Poor outcome has, part, been related to increased inflammation, poor angiogenesis, and deficiencies extracellular matrix components. Despite the enormous impact these chronic wounds, effective therapies are lacking. Here, we showed that topical application recombinant matricellular protein angiopoietin-like 4 (ANGPTL4) accelerated reepithelialization mice, by improving angiogenesis. ANGPTL4 expression markedly...
Mesenchymal stem cells (MSCs) possess inherent tropism towards tumor cells, and so have attracted increased attention as targeted-therapy vehicles for glioma treatment.The objective of this study was to demonstrate the injection MSCs loaded with paclitaxel (Ptx)-encapsulated poly(d,l-lactide-co-glycolide) (PLGA) nanoparticles (NPs) orthotopic therapy in rats.Ptx-PLGA NP-loaded MSC obtained by incubating Ptx-PLGA NPs. The drug transfer cytotoxicity against were investigated transwell system....
Soft structures in nature, such as supercoiled DNA and proteins, can organize into complex hierarchical architectures through multiple noncovalent molecular interactions. Identifying new classes of natural building blocks capable facilitating long-range structuring has remained an elusive goal. We report the bottom-up synthesis a metal-phenolic mesocrystal where self-assembly proceeds on different length scales spatiotemporally controlled manner. Phenolic-based coordination complexes...
NMR and MRI were employed to analyze the water uptake distribution during rehydration processing of lightly dried sea cucumbers. Good linear correlations observed between parameters texture profile analysis.
Abstract Extracellular matrix protein-1 (ECM1) promotes tumorigenesis in multiple organs but the mechanisms associated to ECM1 isoform subtypes have yet be clarified. We report this study that secretory ECM1a induces through GPR motif binding integrin αXβ2 and activation of AKT/FAK/Rho/cytoskeleton signaling. The ATP cassette subfamily G member 1 (ABCG1) transduces ECM1a-integrin interactive signaling facilitate phosphorylation AKT/FAK/Rho/cytoskeletal molecules confer cancer cell cisplatin...
Nano-/microplastics accumulate in aquatic bodies and raise increasing threats to ecosystems human health. The limitation of existing water cleanup strategies, especially the context nano-/microplastics, primarily arises from their complexity (morphological, compositional, dimensional). Here, highly efficient bio-based flowthrough capturing materials (bioCap) are reported remove a broad spectrum nano-/microplastics water: polyethylene terephthalate (anionic, irregular shape), (net neutral,...
Abstract Photoelectric synaptic devices with optical sensing capability are of great importance in simulating human vision systems. Especially realizing all‐in‐one neuristor on silicon based new materials and principles is being pursued. 2D van der Waals (vdW) have the unique advantage arbitrary stacking demand. Herein, a full‐vdW two‐terminal ferroelectric α ‐In 2 Se 3 /SnSe p–n heterojunction proposed to construct an optoelectronic simulate visual functions. Implementation these...