A5019966892- Natural product bioactivities and synthesis
- Pharmacological Effects of Natural Compounds
- Phytochemistry and Biological Activities
- Ginseng Biological Effects and Applications
- Traditional Chinese Medicine Analysis
- Medicinal plant effects and applications
- Biochemical Analysis and Sensing Techniques
- Dyeing and Modifying Textile Fibers
- Carbon Nanotubes in Composites
- Advanced Photocatalysis Techniques
- Catalytic Processes in Materials Science
- Hair Growth and Disorders
- Skin Protection and Aging
- Phytochemicals and Antioxidant Activities
- Phytochemistry and biological activity of medicinal plants
- Nanomaterials for catalytic reactions
- Plant Stress Responses and Tolerance
- Graphene research and applications
- Phytochemistry and Bioactive Compounds
- Plant biochemistry and biosynthesis
- Biological Activity of Diterpenoids and Biflavonoids
- Skin and Cellular Biology Research
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Phytochemical Studies and Bioactivities
- Copper-based nanomaterials and applications
Osaka University
2022-2025
Chongqing University
2020-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2022-2025
First Affiliated Hospital of Kunming Medical University
2024-2025
Kunming Medical University
2024-2025
Shandong University
2025
State Key Laboratory of Reproductive Medicine
2025
Xinjiang Agricultural University
2025
National Center for Nanoscience and Technology
2021-2024
University of Chinese Academy of Sciences
2021-2024
Nano-/microplastics accumulate in aquatic bodies and raise increasing threats to ecosystems human health. The limitation of existing water cleanup strategies, especially the context nano-/microplastics, primarily arises from their complexity (morphological, compositional, dimensional). Here, highly efficient bio-based flowthrough capturing materials (bioCap) are reported remove a broad spectrum nano-/microplastics water: polyethylene terephthalate (anionic, irregular shape), (net neutral,...
Psoriasis is an intractable immune-mediated disorder that disrupts the skin barrier. While studies have dissected mechanism by which immune cells directly regulate epidermal cell proliferation, involvement of dermal fibroblasts in progression psoriasis remains unclear. Here, we identified signals from dendritic (DCs) migrate to dermal-epidermal junction region enhance stiffness increasing extracellular matrix (ECM) expression, further promotes basal hyperproliferation. We analyzed cell-cell...
The global emergence of multidrug-resistant (MDR) bacteria is a growing threat to public health worldwide. Natural bacteriophage lysins are promising alternatives in the treatment infections caused by Gram-positive pathogens, but not Gram-negative ones, like Acinetobacter baumannii and Pseudomonas aeruginosa, due barriers posed their outer membranes. Recently, modifying natural lysin with an antimicrobial peptide was found able break barriers, kill pathogens. Herein, new peptide-modified...
Digital inkjet printing on high-class wool textiles is in line with the trend, but challenge such as reducing impact of scales print quality still worth attention. In this study, a novel environment-friendly method was applied to pretreatment without any generation hazardous substances. H2O2 and papain were adopted pretreat fabric before process. Both wettability zeta potential treated improved obviously. Moreover, Fourier-transform infrared spectroscopy spectra X-ray photoelectron proved...
The clustered regularly interspaced short palindromic repeat/CRISPR-associated protein 9 (CRISPR/Cas9) technology is an efficient genome editing tool used in multiple plant species. However, it has not been applied to Tartary buckwheat (Fagopyrum tataricum), which important edible and medicinal crop rich rutin other flavonoids. FtMYB45 R2R3-type MYB transcription factor that negatively regulates flavonoid biosynthesis buckwheat. Here, the CRISPR/Cas9 system polycistronic tRNA-sgRNA...
Rationale: Stem cells self-organize to form organoids that generate mini-organs resemble the physiologically-developed ones.The mechanism by which stem acquire initial potential for generating remains elusive.Here we used skin as an example study how mechanical force drives epidermal-dermal interaction potentiates regenerate hair follicles.Methods: Live imaging analysis, single-cell RNA-sequencing and immunofluorescence were analyze contractile of dermal in organoids.Bulk calcium probe...
Streptococcus mutans often survives as a biofilm on the tooth surface and contributes to development of dental caries. We investigated efficacy ClyR, an engineered chimeolysin, against S. biofilms under physiological cariogenic conditions. Susceptibility tests showed that ClyR was active all clinical isolates tested well displayed resistance penicillin. The formed hydroxyapatite discs sugar conditions were reduced ∼2 logs 3 after treatment with 100 μg/ml respectively. In comparison, only...
Pt nanoparticles encapsulated into zeolite Y (denoted as Pt@Y) exhibited approaching 100% catalytic selectivity to 2,5-bis-(hydroxymethyl)-furan (BHMF) at full conversion of 5-hydroxymethylfurfural (HMF) in the presence H2, coupled with good reusability. Zeolite constrained HMF be adsorbed on nanoparticle surface via either end aldehyde groups or hydroxyl thermodynamically unfavorable end-on mode enlarge gap activation energies between hydrogenation and hydrodehydroxylation favor enhancement...
Artemisia argyi is a valuable traditional medicinal plant in Asia. The essential oil from its leaves rich terpenoids and has been used to enhance health well-being. In China, the market scale of industries related A. attained tens billions Chinese Yuan. basic helix-loop-helix (bHLH) family one largest transcription factors families plants that plays crucial roles diverse biological processes an regulatory component terpenoid biosynthesis. However, bHLH TFs their remain unknown. Here, 53...
The early gonads of mammals contain primordial germ cells (PGCs) and somatic cell precursors that are essential for sex determination gametogenesis. Although it is extensively documented in mice, the development non-rodents remains to be delineated. Because molecular differences between mouse human gonadal have been reported, warrants study key markers regulatory features conserved or divergent non-rodent species human. Here, we integrate single-cell transcriptome chromatin accessibility...
Pinellia ternata (Thunb.) Druce is a traditional medicinal plant containing variety of alkaloids, which are important active ingredients. Brassinolide (BR) hormone that regulates response to environmental stress and promotes the accumulation secondary metabolites in plants. However, regulatory mechanism BR-induced alkaloid P. not clear. In this study, we investigated effects BR biosynthesis inhibitor (propiconazole, Pcz) treatments on bulbil ternata. The results showed total content yield...
Stem cells in organoids self-organize into tissue patterns with unknown mechanisms. Here, we use skin to analyze this process. Cell behavior videos show that the morphological transformation from multiple spheroidal units morphogenesis competence (CMU) planar is characterized by two abrupt cell motility–increasing events before calming down. The self-organizing processes are controlled a morphogenetic module composed of molecular sensors, modulators, and executers. Increasing dermal...