- Extracellular vesicles in disease
- Circular RNAs in diseases
- Advanced biosensing and bioanalysis techniques
- MicroRNA in disease regulation
- Adenosine and Purinergic Signaling
- Innovative Microfluidic and Catalytic Techniques Innovation
- RNA Research and Splicing
- Microfluidic and Capillary Electrophoresis Applications
- Gold and Silver Nanoparticles Synthesis and Applications
- Cancer Genomics and Diagnostics
- Cancer-related molecular mechanisms research
- Electrowetting and Microfluidic Technologies
- Genetics and Neurodevelopmental Disorders
- Nanopore and Nanochannel Transport Studies
Southern Medical University
2023-2025
Nanfang Hospital
2023-2025
Cell Technology (China)
2024-2025
Abstract Monitoring tumor biomarkers in a non‐invasive manner for diagnosis has attracted increasing attention. Liquid biopsy mainly includes three types of biomarkers: circulating cells, extracellular vesicles, and nucleic acids. These released by cells can travel to other parts the circulation system. The analysis markers enables early diagnosis, progression evolution, treatment monitoring, which are important individualized clinical decisions. In this study, we summarize different DNA...
Circular RNAs in extracellular vesicles (EV-circRNAs) are gaining recognition as potential biomarkers for the diagnosis of gastric cancer (GC). Most current research is focused on identifying new and their functional significance disease regulation. However, practical application EV-circRNAs early GC yet to be thoroughly explored due low accuracy analysis. In this study, a hybridization chain reaction system based rectangular DNA framework guidance constructing bimodal EV-circRNA situ...
The utility of circular RNAs (circRNAs) as emerging biomarkers and regulatory factors in medical diagnostics therapeutics is hampered by the challenges associated with their sensitive detection precise modulation. Herein, a high‐performance cooperative DNA nanodevice (HCDN) based on tetrahedron‐confined catalytic assembly reaction (DT‐CDA) that enables both imaging regulation circRNAs developed. Activation DT‐CDA contingent upon presence target circRNA, which, together replicative fuel...