Huijun Du

ORCID: 0000-0001-5393-1560
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About
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Research Areas
  • Ferroptosis and cancer prognosis
  • Network Security and Intrusion Detection
  • Conducting polymers and applications
  • RNA modifications and cancer
  • Perovskite Materials and Applications
  • Cancer-related molecular mechanisms research
  • Cancer Cells and Metastasis
  • Cancer, Lipids, and Metabolism
  • Smart Grid Security and Resilience
  • Organic Electronics and Photovoltaics
  • Advanced Malware Detection Techniques
  • Circular RNAs in diseases
  • Advanced Sensor and Energy Harvesting Materials
  • MicroRNA in disease regulation
  • Blockchain Technology Applications and Security
  • Extracellular vesicles in disease
  • Pharmacological Effects of Natural Compounds
  • Bone and Joint Diseases
  • Hydrogen's biological and therapeutic effects
  • Cardiovascular Disease and Adiposity
  • Cancer Immunotherapy and Biomarkers
  • Ginger and Zingiberaceae research
  • Sodium Intake and Health
  • Fibroblast Growth Factor Research
  • Advanced Neural Network Applications

Zhejiang University
2025

Shanghai Electric (China)
2023-2024

Guangzhou Medical University
2024

South China University of Technology
2023

Harbin Medical University
2021-2023

Fourth Affiliated Hospital of Harbin Medical University
2021-2023

Center for Life Sciences
2023

Tsinghua University
2023

Chongqing Normal University
2022

Zhongyuan University of Technology
2022

<title>Abstract</title> <bold>Background:</bold> Hypertensive heart disease (HHD), a progressive condition with significant morbidity and mortality, remains poorly understood at the molecular mechanistic level.<bold>Methods:</bold> We first analyzed latest trends in HHD using data from Global Burden of Disease Study 2021. Correlations between immune-inflammatory indices were explored continuous National Health Nutrition Examination Survey (NHANES) datasets 2015–2018. Transcriptomic analyses...

10.21203/rs.3.rs-6079057/v1 preprint EN cc-by Research Square (Research Square) 2025-03-11

Abstract Minimizing energy loss in organic solar cells (OSC S ) is critical for attaining high photovoltaic performance. Among the parameters that correlated to performance, offsets between donor–acceptor pairs play a vital role photoelectric conversion processes. For so far reported large number of non‐fullerene acceptors (NFAs), only Y6 and its derivatives can achieve external quantum efficiencies (EQEs) over 80% with negligible when combined polymeric donors. Thus, understanding...

10.1002/aenm.202301965 article EN Advanced Energy Materials 2023-12-26

The utility of circular RNAs (circRNAs) as emerging biomarkers and regulatory factors in medical diagnostics therapeutics is hampered by the challenges associated with their sensitive detection precise modulation. Herein, a high‐performance cooperative DNA nanodevice (HCDN) based on tetrahedron‐confined catalytic assembly reaction (DT‐CDA) that enables both imaging regulation circRNAs developed. Activation DT‐CDA contingent upon presence target circRNA, which, together replicative fuel...

10.1002/sstr.202400255 article EN cc-by Small Structures 2024-08-06

Abstract Lead halide perovskites are attractive light source candidates for new amplifiers and lasers in the growing field of short‐distance data communication. However, presence plenty defects poor stability major obstacle to production application perovskite optoelectronic devices. Three strategies proposed prepare MAPbI 3 films with high enhanced amplification this study: 1) prepared ionic liquid methylammonium acetate (MAAc) improve quality films; 2) a poly(methyl methacrylate) (PMMA)...

10.1002/adom.202201328 article EN Advanced Optical Materials 2022-09-21

DTL has been found to be related with multiple cancers. However, comprehensive analyses, which identify the prediction value of in diagnosis, prognosis, immune infiltration and treatment, have rarely reported so far.Combined data online databases, gene expression, mutation, function enrichment correlations immunity status clinical indexes were analyzed. Expression degree cell examined by immunofluorescence (IF) immunohistochemistry (IHC) analyzed statistical analysis. Furthermore, influences...

10.1186/s12885-023-10755-z article EN cc-by BMC Cancer 2023-04-10

The development of efficient stretchable organic photovoltaics (OPVs) poses a challenge that requires addressing the coupling morphology and electronic structure in donor/acceptor blended thin films, which represents interplay between mechanical deformation photophysical performance. In this study, intrachain modification is employed to enhance stretchability conjugated polymers PTzBI-Si P(NDI2OD-T2), well-studied combination all-polymer solar cells. By introducing segments...

10.1021/acs.macromol.3c01349 article EN Macromolecules 2023-10-30

Background Ferroptosis is widely involved in the occurrence and development of various cancers, but a specific mechanism involving ferroptosis cervical cancer still unclear. Methods Based on expressions ferroptosis-related genes, prognostic model was constructed using lasso regression, overall predictive performance this verified. An in-depth analysis then conducted. Results The showed good both validation test sets. Mechanism indicated that differences tumor microenvironment were basis...

10.3389/fendo.2022.991178 article EN cc-by Frontiers in Endocrinology 2022-10-14

Background Thyroid cancer is the most common malignant tumor of endocrine system. Most patients with thyroid have a good prognosis, although small proportion experience recurrence and metastasis poor prognosis. Ferroptosis novel form regulated cell death (RCD); previous studies confirmed that ferroptosis was associated cancer. The purpose this study to investigate key ferroptosis-related genes in their relationship prognosis immune infiltration. Methods In study, 497 RNA expression datasets...

10.3389/fendo.2022.997873 article EN cc-by Frontiers in Endocrinology 2022-11-04

Purpose: Hydrogen (H2) is an antioxidant with anti-inflammatory and apoptosis functions.This study aimed to estimate the effects of H2 on acute myocardial infarction (AMI) in rats its association inhibition oxidative stress cardiomyocyte pyroptosis.Methods: Sixty-four were randomly divided into three groups (Sham, AMI, H2).The left anterior descending coronary artery (LAD) AMI was ligated, while Sham group threaded without ligation.In addition, 2% administered by inhalation for 24 h after...

10.7150/ijms.61329 article EN cc-by-nc International Journal of Medical Sciences 2021-01-01

Paracrine signals play pivotal roles in organ homeostasis. Mesenchymal stromal cells (MSCs) a key role regulating epithelium homeostasis the intestine while their paracrine effects are poorly characterized. Here, we identified prostaglandin E2 (PGE2) secreted by cyclooxygenase (COX)-expressing MSCs as vital factor to maintain intestinal mucosal barrier. We found that MSCs-induced organoid swelling through effect vitro, process due enhanced water adsorption and is mediated COX-PGE2-EP4 axis....

10.1186/s13619-023-00174-7 article EN cc-by Cell Regeneration 2023-08-14

Abstract With the continuous improvement of intelligence level State Grid, data security protection in power system automation has become an important challenge for development enterprises. In order to solve this problem, article is based on research structure, types, and current status protection, combined with computer electronics technology, conduct in-depth automation, establish a model its theoretical foundation. verify effectiveness model, paper tested it from three dimensions: degree,...

10.1088/1742-6596/2774/1/012024 article EN Journal of Physics Conference Series 2024-07-01

A triboelectric nanogenerator (TENG) provides an effective method to harvest mechanical energy from the environment. The morphology and structure of frictional electrode materials this type device affect output performance significantly. Metal-organic coordination polymers (CPs) with special advantages offer a vast pool enabling high performances. Two Co-CPs based on terephthalic acid 2,5-dihydroxyterephthalic ligands, respectively, were used fabricate TENGs. Detailed electrical...

10.1039/d2ra05537f article EN cc-by-nc RSC Advances 2022-01-01

With the rapid development of information technology, systems are becoming increasingly complex, which also brings more security challenges. Vulnerabilities weaknesses in that can be maliciously exploited to attack system. In order effectively protect system from attack, vulnerability elimination technology based on runtime self-protection is developed. Therefore, this paper focuses overview run-time demand analysis key mechanism and describes implementation process detail. Finally, results...

10.1109/asim62342.2023.00042 article EN 2023-12-22

Objective To compare the recessive and dominant blood loss total during perioperative period between proximal femoral nail antirotation (PFNA) artificial head replacement in treatment of Evans Ⅲ, Ⅳ type intertrochanteric fractures for providing clinical evidence on selection operative methods. Methods A retrospective study was conducted to analyze 61 older hospitalized patients with Jimo City Traditional Chinese Medical Hospital from January 2009 September 2014.The PFNA adopted 33...

10.3760/cma.j.issn.0254-9026.2018.01.017 article EN Zhonghua laonian yixue zazhi 2018-01-14

The construction of power IoT (Internet things) will greatly change the existing business model and professional system, inevitably impact data storage security business. Due to negligence or omission database designer in process designing developing database, there are a lot holes which makes attacker successfully attack database. In this paper, research on vulnerability mining method based Spark framework RASP technology is carried out. This paper puts forward methodology, can be used mine...

10.1109/ickecs56523.2022.10059626 article EN 2022-12-28
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