Xingren Chen

ORCID: 0009-0007-5751-2313
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Environmental Quality and Pollution
  • Epigenetics and DNA Methylation
  • Heavy metals in environment
  • Blockchain Technology Applications and Security
  • Analytical Chemistry and Chromatography
  • Peroxisome Proliferator-Activated Receptors
  • Chronic Kidney Disease and Diabetes
  • GDF15 and Related Biomarkers
  • Geochemistry and Geologic Mapping
  • Healthcare Operations and Scheduling Optimization
  • Renal Diseases and Glomerulopathies
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Analytical Methods in Pharmaceuticals
  • Parathyroid Disorders and Treatments
  • Nanopore and Nanochannel Transport Studies
  • Histone Deacetylase Inhibitors Research
  • Nuclear Receptors and Signaling
  • Concrete and Cement Materials Research
  • Inflammasome and immune disorders
  • Cloud Computing and Resource Management
  • Bone Metabolism and Diseases
  • Asphalt Pavement Performance Evaluation
  • Supercapacitor Materials and Fabrication
  • Bone health and treatments
  • Digital Imaging in Medicine

Hangzhou Dianzi University
2025

Harbin Institute of Technology
2024

Minzu University of China
2023

State Ethnic Affairs Commission
2023

Nanjing Drum Tower Hospital
2019-2021

Nanjing University
2019-2021

Northeastern University
2019-2020

Model Animal Research Center
2019

Anhui Geological Museum
2008-2012

Abstract Osteoporosis (OP) is a common skeletal disease involving low bone mineral density (BMD) that often leads to fragility fracture, and its development affected by multiple cellular pathologies associated with marked epigenetic alterations of osteogenic genes. Proper physical exercise beneficial for health OP reportedly possesses modulating capacities; however, whether the protective effects on involve mechanisms unclear. Here, we report derepression nuclear factor erythroid derived...

10.1038/s41413-020-00128-8 article EN cc-by Bone Research 2021-02-26

Osteomyelitis is a severe bone infection and typically leads to progressive resorption, destruction dysfunction. Pyroptosis form of programmed cell death involved in various infectious diseases. However, the identification pyroptosis role it plays osteomyelitis remains be clarified. In this study, we investigated expression pyroptosis-associated proteins effects inhibiting on S. aureus-induced both vitro vivo.The protein-NLRP3 (NLR Family Pyrin Domain Containing 3), Caspase1 GSDMD...

10.21037/atm.2019.03.40 article EN Annals of Translational Medicine 2019-04-01

Background and Purpose Development of pulmonary fibrosis is associated with altered DNA methylation modifications fibrogenic gene expression. However, their causal relationships the underlying mechanisms remain unclear. This study investigates critical role aberration‐associated suppression peroxisome proliferator‐activated receptor‐γ (PPARγ) in fibrosis. Experimental Approach Expression PPARγ bioactive methyltransferases (DNMTs) promoter status were examined fibrotic lungs idiopathic (IPF)...

10.1111/bph.15655 article EN British Journal of Pharmacology 2021-08-11

We have developed an efficient automated platform to facilitate the construction of different simulated polyamide membranes, which has been validated in two example systems.

10.1039/d4ra08955c article EN cc-by-nc RSC Advances 2025-01-01

As the society is aging, increasing prevalence of osteoporosis has generated huge social and economic impact, while drug therapy for limited due to multiple targets involved in this disease. Zhuangguguanjie formulation (ZG) extensively used clinical treatment bone joint diseases, but underlying mechanism not been fully described. This study aimed examine therapeutic effect potential ZG on postmenopausal osteoporosis. The ovariectomized (OVX) mice were treated with normal saline or 4 weeks...

10.3389/fphar.2021.727808 article EN cc-by Frontiers in Pharmacology 2021-10-01
Coming Soon ...