A5061600894- Forensic Toxicology and Drug Analysis
- Psychedelics and Drug Studies
- Poisoning and overdose treatments
- Cannabis and Cannabinoid Research
- Veterinary Pharmacology and Anesthesia
- Alcohol Consumption and Health Effects
- Opioid Use Disorder Treatment
- Neurotransmitter Receptor Influence on Behavior
- Neonatal Health and Biochemistry
- Methemoglobinemia and Tumor Lysis Syndrome
- Anesthesia and Sedative Agents
- Legal and Policy Issues
- Analytical Methods in Pharmaceuticals
- Pain Management and Opioid Use
Florida College
2020-2025
University of Florida
2015-2025
American Academy of Forensic Sciences
2023
Abstract The emergence of new psychoactive substances (NPS) and the number chemically diverse in global illicit drug market have significantly increased over last few years. Designer benzodiazepines are some most misused NPS worldwide, contributing to both nonfatal fatal overdose cases. use desalkylgidazepam bromazolam has recently emerged, their prevalence been internationally reported. In this study, we quantified using gas chromatography coupled with mass spectrometry (GC–MS) postmortem...
Designer benzodiazepines are a commonly misused class of novel psychoactive substances (NPS) that present challenges for forensic toxicology laboratories and public health. Due to the difficulty in detection by routine methods, it is important enhance analytical methods identification quantitation designer benzodiazepines. The aim this study was identify quantify using gas chromatography coupled with mass spectrometry (GC-MS) postmortem blood specimens. A method originally validated...
Abstract Synthetic stimulants are the largest class of novel psychoactive substances identified each year by forensic laboratories internationally. While hundreds these drugs appear in drug powders, only a few proliferate use among forensically relevant populations and eventually emerge postmortem clinical investigations. Beta-keto-methylenedioxyamphetamines (i.e., with names ending “ylone”) currently most popular subclass synthetic stimulants. Leading up to its federal scheduling 2018,...
Synthetic cathinones are an emerging class of designer drugs, frequently with deceptive labels and a multitude analogs to circumvent drug control regulations. Research regarding the pharmacological effects toxicity these amphetamine derivatives is scarce, heightening risk public health safety. The composition synthetic cathinone products continually changes laboratories began notice ethylone-positive in late 2011. This report presents nine postmortem cases whom ethylone was identified....
The opioid epidemic continues to evolve in the USA, with fentanyl most prevalent synthetic fatal drug overdoses. Following scheduling of fentanyl's core structure 2018, there was a notable decline prevalence analogs decedents; however, fluorofentanyl began being reported casework winter 2020. Fluorofentanyl has three positional isomers (para-fluorofentanyl (p-FF), ortho-fluorofentanyl (o-FF) and meta-fluorofentanyl (m-FF)), predominant isomer that recently emerged USA p-FF. goal this study...
The intentional ingestion of sodium nitrite causes toxicity by inducing methemoglobinemia, which can lead to cyanosis, hypotension and death. number reported suicide cases has significantly increased in the past 10 years as is readily available online. traditional tests for nitrate require specialized detection methods are not typically a postmortem toxicology laboratory. This rise overdose indicates need simple, quick test suspected toxicity. In this study, common Griess reagent color...
Novel synthetic opioids contribute considerably to the opioid epidemic, especially with frequent emergence of structurally similar compounds. This case report describes a fatal intoxication involving 2-methyl AP-237. A 54-year-old Caucasian male was found deceased from an apparent drug overdose. plastic container labeled "2MAP" and cut straw were in decedent's backpack at scene. white substance tested positive for fentanyl by field testing. According his medical history, decedent treated...
Laws concerning the growing, selling and consuming of cannabis its related products have been changing considerably over last few years. The legalization hemp in 2018 sparked an interest ∆9-tetrahydrocannabinol (∆9-THC) isomers analogs that are derived from sold with minimal oversight. One example is ∆8-tetrahydrocannabinol (∆8-THC). Although less potent than ∆9-THC, ∆8-THC gaining popularity can easily be found where cannabis-related sold. Forensic Toxicology Laboratory at University...