A5025668946- Metal Extraction and Bioleaching
- Corrosion Behavior and Inhibition
- Bacterial biofilms and quorum sensing
- Minerals Flotation and Separation Techniques
- Antibiotic Resistance in Bacteria
- Enzyme Production and Characterization
- Bacterial Genetics and Biotechnology
- Metal and Thin Film Mechanics
- Wound Healing and Treatments
- Microbial Natural Products and Biosynthesis
- Food Safety and Hygiene
- Microbial Fuel Cells and Bioremediation
- Microbial Metabolism and Applications
- Extraction and Separation Processes
- Innovative concrete reinforcement materials
- Integrated Circuits and Semiconductor Failure Analysis
- Infections and bacterial resistance
- Cassava research and cyanide
- Electrospun Nanofibers in Biomedical Applications
- Cancer Research and Treatments
- Burn Injury Management and Outcomes
- Antifungal resistance and susceptibility
- Innovative Microfluidic and Catalytic Techniques Innovation
- Vibrio bacteria research studies
University of Chile
2013-2024
Costa Rican Department of Social Security
2024
Universidad Mayor
2013
Acidophile bacteria belonging to the Acidithiobacillus genus are pivotal players for bioleaching of metallic values such as copper. Cell adherence ores and biofilm formation, mediated by production extracellular polymeric substances, strongly favors activity. In recent years, second messenger cyclic diguanylate (c-di-GMP) has emerged a central regulator formation in bacteria. C-di-GMP pathways have been reported different species; however, c-di-GMP effectors signal transduction networks...
The emergence of hypervirulent Klebsiella pneumoniae (hvKP) strains poses a significant threat to public health due high mortality rates and propensity cause severe community-acquired infections in healthy individuals. ability form biofilms produce protective capsule contributes its enhanced virulence is challenge effective antibiotic treatment. Polyphosphate kinase 1 (PPK1) an enzyme responsible for inorganic polyphosphate synthesis plays vital role regulating various physiological...
Cyclic and linear nucleotides are key elements of the signal transduction networks linking perception environment to specific cellular behavior prokaryotes. These molecular mechanisms particularly important in bacteria exposed different, frequently simultaneous, types extreme conditions. This is case acidithiobacilli, a group extremophilic thriving highly acidic biotopes, that must also cope with significant variations temperature, osmotic potentials concentrations various transition metals...
Acidithiobacillus species are fundamental players in biofilm formation by acidophile bioleaching communities. It has been previously reported that ferrooxidans possesses a functional quorum sensing mediated acyl-homoserine lactones (AHL), involved formation, and AHLs naturally produced also induce thiooxidans. A c-di-GMP pathway characterized but it pointed out the effector PelD pel-like operon only present sulfur oxidizers such as A. PEL exopolysaccharide recently this species. Here,...
The presence of extracellular polymeric substances (EPS) is important in the building biofilms on mineral surfaces, increasing bioleaching activity, as well protecting cells from adverse environmental conditions. objective this work was to study effect galactose EPS production by Acidithiobacillus ferrooxidans . experiences were performed shake flask 250 mL at 30 °C, 200 rpm and an initial pH 1.8. In order establish natural tolerance strain, its growth behaviour evaluated high ferric iron...
Extracellular polymeric substances (EPS) play an important role in the attachment of bacteria to sulphide minerals, biofilm formation and efficiency bioleaching process. Previous studies have suggested a potential connection between galactose EPS formation. In this context, influence exogenous on during pyrite was studied. order fully adapt microorganism conditions it performed total five consecutive sub cultures, one every fifteen days, taking for each inocula from previous culture shake...
Bioleaching is the solubilization of metals catalyzed by acidophilic microorganisms. Among these, Gram negative γ-proteobacteria from genus Acidithiobacillus play a relevant role. Biofilm formation has an impact on bioleaching performance. In sp. molecular mechanisms involved in biofilm are still unknown. However, many Gram-negative and some Gram-positive bacteria, intracellular levels second messenger cyclic diguanilic acid (c-di-GMP) control regulation formation. These depend balance...
The Acidithiobacillus genus plays a relevant role in bioleaching. molecular understanding of biofilm formation has been pointed out to design biological strategies improve the efficiency this industrial process and prevent environmental damages caused by acid mine/rock drainages. In spp., mechanisms involved are currently emerging. second messenger cyclic diguanylate (c-di-GMP) appears as key player for sp. Here, results obtained from genomic analysis characterize c-di-GMP pathway At....
The ability of Acidithiobacillus ferrooxidans to get its energy from the oxidation ferrous iron and inhibitory effect high ferric concentrations on growth behaviour has been extensively studied. Furthermore it is known that A. exudes organic substances called extracellular polymeric (EPS), which could play a role in protection against adverse environmental conditions. In this context, aim work was study production EPS during adaptation ion concentrations. experiments were performed shake...
Se presenta el caso de un paciente quien acude al servicio urgencias médicas por cuadro infección tejidos blandos, con evolución a shock séptico fulminante refractario y posterior fallecimiento en menos 24 horas; como agente causal se identifica Vibrio cholerae cepa no-01 no-O139; microorganismo descrito muy poca frecuencia este cuadro. Como factores riesgo solo identificó hepatopatía no especificada. Este es primero Costa Rica, aunque la bacteria poco frecuente, necesario considerarlo los...
ABSTRACT The emergence of hypervirulent Klebsiella pneumoniae (hvKP) strains poses a significant threat to public health due their high mortality rates and propensity cause severe community-acquired infections in otherwise healthy individuals. ability hvKP form biofilms produce protective capsule contributes its enhanced virulence is challenge effective antibiotic treatment. Therefore, understanding the molecular mechanisms underlying biofilm formation crucial for developing new therapeutic...