Nicolás Gonzalez

ORCID: 0000-0003-3351-8714
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About
Contact & Profiles
Research Areas
  • Surgical Simulation and Training
  • Anatomy and Medical Technology
  • Augmented Reality Applications
  • Spinal Fractures and Fixation Techniques
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Medical Imaging and Analysis
  • Intracranial Aneurysms: Treatment and Complications
  • Cardiovascular Function and Risk Factors
  • Colorectal Cancer Screening and Detection
  • Gastric Cancer Management and Outcomes
  • Acute Myocardial Infarction Research
  • Vascular Malformations Diagnosis and Treatment
  • Multiple Myeloma Research and Treatments
  • Trauma and Emergency Care Studies
  • Esophageal Cancer Research and Treatment
  • Heart Failure Treatment and Management
  • Immune cells in cancer
  • Colorectal Cancer Surgical Treatments
  • Extracellular vesicles in disease
  • Meningioma and schwannoma management
  • Cholinesterase and Neurodegenerative Diseases
  • Geodetic Measurements and Engineering Structures
  • Remote Sensing in Agriculture
  • Diabetes Management and Research
  • Intracerebral and Subarachnoid Hemorrhage Research

St. Joseph's Hospital and Medical Center
2022-2024

Barrow Neurological Institute
2022-2024

Universidad de La Frontera
2024

Hospital Británico
2021-2024

University of Chile
2020-2023

University of California, Irvine
2023

Harvard University
2021

University of Maryland, Baltimore
2021

Center for Cancer Research
2021

Massachusetts General Hospital
2021

Advances in computer sciences, including novel 3-dimensional rendering techniques, have enabled the creation of cloud-based virtual reality (VR) interfaces, making real-time peer-to-peer interaction possible even from remote locations. This study addresses potential use this technology for microsurgery anatomy education.Digital specimens were created using multiple photogrammetry techniques and imported into a simulated neuroanatomy dissection laboratory. A VR educational program multiuser...

10.25259/sni_162_2023 article EN cc-by-nc-sa Surgical Neurology International 2023-03-17

OBJECTIVE This study sought to assess the use of an augmented reality (AR) tool for neurosurgical anatomical education. METHODS Three-dimensional models were created using advanced photogrammetry and registered onto a handheld AR foam cube imprinted with scannable quick response codes. A perspective analysis system was performed by loading 3D model over motorized turntable analyze changes in surgical window area according horizontal rotation. The as intraoperative reference guide trainees...

10.3171/2023.10.jns23516 article EN Journal of neurosurgery 2024-01-01

Patients with multirefractory immune thrombocytopenia (ITP) have limited treatment options. Recent data suggest that specific anti-platelet antibodies may cause destruction of platelets by favoring platelet loss sialic acid. In this multicenter study 35 patients ITP, including 16 disease, were analyzed for antiplatelet-antibodies, thrombopoietin (TPO) levels, and desialylation. selected cases, responses to a novel strategy using oseltamivir tested.We found against GPIbα overrepresented in...

10.1080/09537104.2018.1513476 article EN Platelets 2018-10-08

Abstract Aim T lymphocytes play a central role during the pathogenesis of periodontitis, and imbalance between pathogenic T‐helper type 17 (Th17) protective T‐regulatory (Treg) determines tooth‐supporting alveolar bone resorption. Interleukin (IL)‐35 is novel anti‐inflammatory cytokine with therapeutic properties in diseases whose associated Th17/Treg imbalance; however, its periodontitis has not been established yet. This study aimed to elucidate whether IL‐35 inhibits resorption by...

10.1111/jcpe.13282 article EN Journal Of Clinical Periodontology 2020-03-11

Visualizing and comprehending 3-dimensional (3D) neuroanatomy is challenging. Cadaver dissection limited by low availability, high cost, the need for specialized facilities. New technologies, including 3D rendering of neuroimaging, pictures, videos, are filling this gap facilitating learning, but they also have limitations. This proof-of-concept study explored feasibility combining spatial accuracy reconstructed neuroimaging data with realistic texture fine anatomical details from...

10.3389/fsurg.2022.878378 article EN cc-by Frontiers in Surgery 2022-05-16

Understanding the anatomy of human cerebrum, cerebellum, and brainstem their 3-dimensional (3D) relationships is critical for neurosurgery. Although 3D photogrammetric models cadaver brains 2-dimensional images postmortem brain slices are available, neurosurgeons lack free access to cross-sectional that can be simulated in both augmented reality (AR) virtual (VR).To create AR/VR simulations from cross-sectionally dissected cadaveric specimens brainstem.The Klingler method was used prepare 3...

10.1227/ons.0000000000000703 article EN Operative Neurosurgery 2023-04-21

INTRODUCTION: A comprehensive grasp of the anatomy human cerebrum, cerebellum, and brainstem, along with their intricate 3-dimensional (3D) interconnections, is paramount in neurosurgical practice. While 3D photogrammetric models cadaver brains 2-dimensional images postmortem brain slices exist, accessible cross-sectional brainstem anatomy, compatible both augmented reality (AR) virtual (VR) simulations, are lacking for neurosurgeons. METHODS: Utilizing Klingler method, three cadaveric...

10.1227/neu.0000000000003360_454 article EN Neurosurgery 2025-03-14

Immersive anatomic environments offer an alternative when laboratory access is limited, but current three-dimensional (3D) renderings are not able to simulate the detail and surgical perspectives needed for microsurgical education.To perform a proof-of-concept study of novel photogrammetry 3D reconstruction technique, converting high-definition (monoscopic) images into navigable, interactive, immersive anatomy simulation.Images were acquired from cadaveric dissections open-access...

10.1227/ons.0000000000000544 article EN Operative Neurosurgery 2022-12-23

AIM:To validate high definition endoscopes with Fujinon intelligent chromoendoscopy (FICE) in colonoscopy. METHODS:The image quality of normal white light endoscopy (WLE), that the 10 available FICE filters and a gold standard (0.2% indigo carmine dye) were compared.

10.3748/wjg.15.5266 article EN cc-by-nc World Journal of Gastroenterology 2009-01-01

OBJECTIVE Microanastomosis is one of the most technically demanding and important microsurgical skills for a neurosurgeon. A hand motion detector based on machine learning tracking technology was developed implemented performance assessment during microvascular anastomosis simulation. METHODS microanastomosis using model capable 21 landmarks without physical sensors attached to surgeon’s hands. Anastomosis procedures were simulated synthetic vessels, recorded with microscope external camera....

10.3171/2023.3.focus2380 article EN Neurosurgical FOCUS 2023-06-01

Objective The development of surgical microscope-associated cameras has given rise to a new operating style embodied by hybrid microsurgical and exoscopic operative systems. These platforms utilize specialized camera systems visualize cranial neuroanatomy at various depths. Our study aims understand how different settings in novel exoscope system influence image quality the context neurosurgical procedures. Methods We built an database using captured cadaveric dissection images obtained with...

10.3389/fsurg.2024.1418679 article EN cc-by Frontiers in Surgery 2024-06-25

Anatomical triangles provide neurosurgeons with the specificity required to access deep targets, supplementing more general instructions, such as craniotomy and approach. The infragalenic triangle (IGT), bordered by basal vein of Rosenthal (BVR), precentral cerebellar (PCV), quadrangular lobule cerebellum, is one a system anatomical recently introduced guide dissection brainstem cavernous malformations has not been described in detail. This study aimed quantitatively analyze parameters IGT...

10.3171/2023.6.jns222871 article EN Journal of neurosurgery 2023-09-30

Resumen es: Introduccion El infarto agudo de miocardio (IAM) representa una las principales causas morbimor- talidad en nuestro pais. Tener datos sobre la real...

10.7775/rac.es.v81.i5.1391 article ES Revista Argentina de Cardiología 2013-10-01

Retrospective Case Series.This study aims to evaluate readmission rates, risk factors, and reason for unplanned 30-day readmissions after thoracolumbar spine trauma surgery.A retrospective chart review was conducted patients undergoing operative treatment thoracic or lumbar with open minimally invasive surgical approach at a Level 1 urban center. Patients were divided into two groups based on status. Reason readmission, reoperation injury type, severity, incidence of polytrauma compared...

10.1177/21925682211041045 article EN cc-by-nc-nd Global Spine Journal 2021-09-25

Abstract Background and study aims The adherence to knowledge of physicians about colorectal cancer (CRC) screening surveillance guidelines is still suboptimal, threatening the effectiveness CRC screening. This assessed usefulness a mobile decision support system (MDSS) improve physician ability recommend proper timing intervals for surveillance. Patients methods was binational, single-blinded, randomized clinical trial including gastroenterologists surgeons from Argentina Uruguay....

10.1055/a-1544-4773 article EN cc-by-nc-nd Endoscopy International Open 2021-11-01

Surgical approaches that access the posterior temporal bone require careful drilling motions to achieve adequate exposure while avoiding injury critical structures.

10.3389/fsurg.2024.1441346 article EN cc-by Frontiers in Surgery 2024-10-03
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