A5103749357- HIV Research and Treatment
- HIV/AIDS drug development and treatment
- Lysosomal Storage Disorders Research
- HIV/AIDS Research and Interventions
- Multiple Myeloma Research and Treatments
- Cancer Treatment and Pharmacology
- Glycosylation and Glycoproteins Research
- Hepatitis B Virus Studies
- Hepatitis C virus research
- Trypanosoma species research and implications
- Peptidase Inhibition and Analysis
- Protein Degradation and Inhibitors
- Maternal Mental Health During Pregnancy and Postpartum
- Chronic Myeloid Leukemia Treatments
- Acute Myeloid Leukemia Research
- Parasitic Diseases Research and Treatment
- Influenza Virus Research Studies
- Studies on Chitinases and Chitosanases
- DNA and Nucleic Acid Chemistry
- Poisoning and overdose treatments
- Child and Adolescent Psychosocial and Emotional Development
- Carbohydrate Chemistry and Synthesis
- Chronic Lymphocytic Leukemia Research
- Child Abuse and Trauma
- Peripheral Neuropathies and Disorders
Hospital Universitario Ramón y Cajal
2024
Universidad de Alcalá
2024
Centro de Investigación Biomédica en Red de Salud Mental
2024
Instituto de Salud Carlos III
2024
Instituto Ramón y Cajal de Investigación Sanitaria
2024
University of Sfax
2018
Complejo Hospitalario Universitario de Albacete
2011-2017
Hospital General Universitario de Albacete
2009-2010
Hospital Universitari Germans Trias i Pujol
1998-2001
Fundación Juan March
1999
To assess the impact of long-term virus suppression on peripheral blood CD4 T cells integrated and total HIV-1 DNA loads in patients receiving highly active antiretroviral therapy (HAART).A 10 HIV-1-infected a triple combination (two nucleoside analogues one protease inhibitor) were longitudinally studied to compare loads. quantification was performed using quantitative nested polymerase chain reaction (PCR) genomic mononuclear cell (PBMC) obtained at baseline 48 weeks HAART.All study showed...
The enzymatic replacement therapy (ERT) availability for Gaucher disease (GD) has changed the landscape of disease, several countries have screening programs. These actions promoted early diagnosis and avoided many complications in pediatric patients. In Spain ERT been available since 1993 386 patients included Spanish Registry Disease (SpRGD). aim this study is to analyze impact on characteristics at time initial To A review data SpRGD from patients' diagnosed before 18 years old was...
The development of new antiretroviral agents may improve survival HIV-infected individuals, and therefore chronic viral hepatitis become more relevant in these patients. presence GBV-C/HGV C virus (HCV) RNA were investigated by reverse transcriptase-nested polymerase chain reaction plasma from 168 Spanish patients belonging to four different risk groups: intravenous drug users (IVDUs), hemophiliacs, homosexuals, heterosexuals. GBV-C/HGV-RNA HCV-RNA detected 18% 43% the patients,...
The mechanisms involved in maintaining a latent replication-competent integrated human immunodeficiency virus type 1 (HIV-1) reservoir after successful highly active antiretroviral therapy (HAART) have not been fully described. objective of this study was to assess whether low-level, persistent HIV-1 replication can be detected the protease gene, 10 HIV-1-infected patients who undergone 2 years HAART. Peripheral blood mononuclear cells (PBMCs) were collected from receiving triple-drug...
Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary point, may be published when key planned co-primary or secondary analyses are not yet available. Trial Updates provide an opportunity to disseminate additional results from studies, in JCO elsewhere, for which point has already been reported. In myeloma (MM), measurable residual disease (MRD) is assessed bone marrow (BM). However, less invasive evaluation...
The impact of emergence genetic resistance, soon after the beginning antiretroviral therapy, on genotype other viral loci not implicated in development resistance was studied four human immunodeficiency type 1 (HIV-1)-infected patients subjected to indinavir monotherapy. Two were chosen because they showed no decrease virus load during study period and two selected a rapid decline plasma viraemia initiation therapy rebound 12 weeks treatment. evolution sequences analysed within infected by...
Both childhood adversity (CA) and first-episode psychosis (FEP) have been linked to alterations in cortical thickness (CT). The interactive effects between different types of CAs FEP on CT remain understudied. One-hundred sixteen individuals with (mean age = 23.8 ± 6.9 years, 34% females, 80.2% non-affective FEP) 98 healthy controls (HCs) 24.4 6.2 43% females) reported the presence/absence CA <17 years using an adapted version Childhood Experience Care Abuse (CECA.Q) Retrospective Bullying...
Introduction: Tricyclic antidepressants are used in multiple psychiatric disorders such as depressive syndrome or attention deficit hyperactivity disorder.Acute intoxications by this drug if not treated time, have a high mortality due to the cardiovascular effects that occur body.Objective: Detect acute poisoning tricyclic with analytical values serum of patients who symptoms compatible establish treatment early.Method: Review clinical history urine screening test were positive for and had...