A5041220432- Cancer Genomics and Diagnostics
- Pleural and Pulmonary Diseases
- Occupational and environmental lung diseases
- Molecular Biology Techniques and Applications
- Medical Imaging and Pathology Studies
- DNA Repair Mechanisms
- Genetic factors in colorectal cancer
- Cancer Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Genomics and Rare Diseases
- Hematological disorders and diagnostics
- COVID-19 and healthcare impacts
- Global Cancer Incidence and Screening
- Lung Cancer Diagnosis and Treatment
- Metastasis and carcinoma case studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Chemotherapy-related skin toxicity
University of Turin
2021-2024
Istituti di Ricovero e Cura a Carattere Scientifico
2023
Candiolo Cancer Institute
2023
Coronavirus disease-19 (COVID-19) has spread worldwide since December 2019 and was officially declared a pandemic in March 2020. Due to the rapid transmission high fatality rate, drastic emergency restrictions were issued, with negative impact on routine clinical activities. In particular, Italy, many authors have reported reduction number of breast cancer diagnoses critical problems management patients who accessed units during dramatic first months pandemic. Our study aims analyze global...
Formalin-fixed paraffin-embedded (FFPE) samples represent the cornerstone of tissue-based analysis in precision medicine. Targeted next-generation sequencing panels are routinely used to analyze a limited number genes guide treatment decision-making for advanced-stage patients. The and complexity genetic alterations be investigated rapidly growing; several instances, comprehensive genomic profiling is needed. poor quality material extracted from FFPE may impact feasibility/reliability data....
Germline mutations in the tumor suppressor gene BRCA1-associated protein-1 (BAP1) lead to BAP1 predisposition syndrome (BAP1-TPDS), characterized by high susceptibility several types, chiefly melanoma, mesothelioma, renal cell carcinoma, and basal carcinoma. Here, we present results of our ten-year experience molecular diagnosis BAP1-TPDS, along with a clinical update cascade genetic testing previously reported BAP1-TPDS patients their relatives. Specifically, sequenced germline DNA samples...
ABSTRACT Formalin-fixed-paraffin-embedded (FFPE) samples represent the cornerstone of tissue-based analysis in precision medicine. Targeted next-generation sequencing (NGS) panels are routinely used to analyze a limited number genes guide treatment decision making for advanced stage patients. The and complexity genetic alterations be investigated rapidly growing, several instances comprehensive genomic profiling (CGP) is required. poor quality material extracted from FFPE may impact...