A5015758879- Hearing Loss and Rehabilitation
- Hearing, Cochlea, Tinnitus, Genetics
- Noise Effects and Management
- Speech and Audio Processing
- Vestibular and auditory disorders
- Head and Neck Anomalies
- Ear Surgery and Otitis Media
- Hearing Impairment and Communication
- Delphi Technique in Research
- Cancer-related molecular mechanisms research
- Nasal Surgery and Airway Studies
- Acoustic Wave Phenomena Research
- Connexins and lens biology
- Craniofacial Disorders and Treatments
- Spinal Fractures and Fixation Techniques
- Medical Practices and Rehabilitation
- Pediatric health and respiratory diseases
- Medical Research and Treatments
- Anesthesia and Neurotoxicity Research
- Phonocardiography and Auscultation Techniques
- Multisensory perception and integration
- Dermatologic Treatments and Research
- Connective tissue disorders research
- Underground infrastructure and sustainability
- Cleft Lip and Palate Research
Peking Union Medical College Hospital
2008-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2008-2024
Hainan University
2022
Capital Medical University
2020
Harbin Institute of Technology
2010
MRC Laboratory of Molecular Biology
2008
Institute of Basic Medical Sciences of the Chinese Academy of Medical Sciences
2008
Shanghai Sixth People's Hospital
2006
Shanghai Jiao Tong University
2006
University of California, Irvine
2005
Amplitude modulation (AM) and frequency (FM) are commonly used in communication, but their relative contributions to speech recognition have not been fully explored. To bridge this gap, we derived slowly varying AM FM from sounds conducted listening tests using stimuli with different modulations normal-hearing cochlear-implant subjects. We found that although a limited number of spectral bands may be sufficient for quiet, significantly enhances noise, as well speaker tone recognition....
Previous investigations into the healing and reconstruction of tympanic membrane (TM) perforations have involved animal models with acute TM perforations. A problem perforation model is that most will heal spontaneously, both in animals human beings. second inadequacy they are not analogous to salient beings: Longstanding perforation. The ideal must a permanent, well‐eplthelialized, free from infection. also be subtotal preserve rim for experimental manipulations, chinchilla, we identified...
The present study was aimed to examine the relationship between psychophysical performance in temporal and spectral resolution Mandarin tone recognition noise by cochlear-implant (CI) listeners.Seventeen Nucleus-24 implant users, 10 postlingually deafened 7 prelingually deafened, participated experiments. A 3-interval, forced-choice procedure used measure gap detection pure-tone frequency discrimination at 250 4,000 Hz octave steps. 4-alternative quiet noise. Signal-to-noise ratios (SNRs)...
AbstractAbstractThe benefits of bimodal hearing (cochlear implant and aid in opposite ears) children are well documented English-speaking populations (Ching et al., 2000; Holt 2005) but not much evidence has been reported from using tonal languages. The lexical tones languages heavily loaded with semantic grammatical information, which essentially represented by the fundamental frequency (F0) low-order harmonics speech signal. This unique linguistic feature means that language-speaking CI...
<i>Background:</i> The GJB2 gene, mapping to chromosome 13q12, encodes a gap junction protein, connexin 26, and is responsible for certain forms of congenital deafness, such as DFNB1 DFNA3. Mutations this gene are about one half severe autosomal recessive non-syndromic deafness. <i>Methods:</i> To determine whether mutations major causes deafness in Chinese cochlear implant recipients, we enrolled 115 recipients mutation screening. <i>Results:</i> results...
MAPPID-N was developed to assess the speech-recognition abilities in noise of Mandarin-speaking children on disyllabic words, and lexical tones monosyllabic a picture-identification test format. Twenty-six normal-hearing aged four nine years listened repeatedly materials where spatially mixed with or separated from speech, different signal-to-noise (SNR) ratios, obtain performance-SNR functions SNR for 50% correct scores (SNR-50%). SNR-50% improved age only when speech but not suggesting...
Background Ouabain, a cardiac glycoside that specifically binds to Na/K-ATPase and inhibits its activity, was applied gerbils develop method for studying auditory neuropathy. Methods Ouabain the round window of cochlea in each gerbil by using piece gelfoam with 3 μl or 24 (1 mmol/L) ouabain solution. The changes threshold brainstem response, cochlear function electrocochleography, as well morphological spiral ganglion cells were observed after application hours 96 hours. Results In treated...
The study reports a case of 5-year-old Chinese girl diagnosed with Kabuki make-up Syndrome (KMS). patient showed classic KMS appearance: widely separated eyes, ectropion lateral one-third lower eyelids, flat nasal tip, and prominent ears. Auditory features in this individual included bilateral severe sensorineural hearing loss lack 40 Hz AERP responses identified at 1 year age. received cochlear implant (CI) the left ear when 5 years old, rehabilitation after CI treatment were 3 speech...
Purpose The aim of the study was to assess whether sequential cochlear implantation (CI) with a prolonged interimplant interval (M = 15.2 years) between first and second CIs benefited speech recognition health-related quality life. Method This prospective included 14 prelingually deafened participants who received their CI after years). Additionally, ability over 12-month period bilateral implant use investigated. results test in both quiet noisy conditions were statistically analyzed for...
Objective: To establish an effective detection method to evaluate auditory pathway in patients by electrical evoked middle latency response (EMLR) before artificial cochlear implantation, and analyze the relationship between postoperative hearing rehabilitation cortex functions. Methods: Twenty-three with implant were recruited. EMLR was measured after adjusting depth of anesthesia. The brainstem (EABR) mode monopolar stimulation two-phase alternating current square waves selected....
Objectives: Several reports have underlined the benefits of speechreading (visual-only speech recognition) on recognition in individuals with hearing loss after cochlear implantation (CI). However, factors that would affect ability are unclear. The aim present study is to assess abilities CI users. Methods: A total 104 participants were enrolled this retrospective study. They viewed silent videos sentences being spoken by a model and tasked repeating what they thought had been said. tested...
Chinese tones are considered important in discrimination. However, the relevant reports on auditory central mechanisms concerning limited. In this study, mismatch negativity (MMN), one of event related potentials (ERP), was used to investigate pre-attentive processing tones, and differences between function oddball MMN that control discussed.Ten subjects (six men four women) with normal hearing participated study. A sequence presented these through a loudspeaker, included blocks, block three...