A5101876293- Chemical Synthesis and Reactions
- Chemical Synthesis and Analysis
- Inorganic and Organometallic Chemistry
- Head and Neck Cancer Studies
- Phenothiazines and Benzothiazines Synthesis and Activities
- Synthesis and Characterization of Heterocyclic Compounds
- Asymmetric Synthesis and Catalysis
- Synthesis and Biological Evaluation
- Oxidative Organic Chemistry Reactions
- Fluorine in Organic Chemistry
- Radical Photochemical Reactions
- Quinazolinone synthesis and applications
- Chemical Reaction Mechanisms
- Polyoxometalates: Synthesis and Applications
- Ear and Head Tumors
- Organic Chemistry Cycloaddition Reactions
- Head and Neck Surgical Oncology
- Structural and Chemical Analysis of Organic and Inorganic Compounds
- Dysphagia Assessment and Management
- Diet and metabolism studies
- Ophthalmology and Visual Impairment Studies
- Intraocular Surgery and Lenses
- Axial and Atropisomeric Chirality Synthesis
- Synthesis and biological activity
- Metabolism and Genetic Disorders
University of Turin
1992-2016
Mount Sinai Medical Center
2011
Ospedale "Floraspe Renzetti"
2005
Zambon (Italy)
1985-1997
Politecnico di Milano
1987-1993
University of Reading
1987
Georgetown University
1984
University of Groningen
1981
Edison (Italy)
1971
University of Pisa
1969
Severe corneal damage leads to complete vision loss, thereby affecting life quality and impinging heavily on the healthcare system. Current clinical approaches manage wounds suffer from severe drawbacks, thus requiring development of alternative strategies. Of late, mesenchymal stromal/stem cell (MSC)-derived extracellular vesicles (EVs) have become a promising tool in ophthalmic field. In present study, we topically delivered bone-marrow-derived MSC-EVs (BMSC-EVs), embedded methylcellulose,...
Encephalitozoon cuniculi is a microsporidium with wide range of mammalian hosts. In rabbits it can be responsible for cataract and lens-induced uveitis (LIU). The aim this study was to provide specific immunohistochemical demonstration localization E. within the eye, in LIU.Four were presented white mass eye iris discoloration. Complete ophthalmic examinations performed presumptive diagnosis LIU made all cases. Initial therapy topical steroid, atropine systemic enrofloxacin instituted while...
The neuronal ceroid lipofuscinoses (NCLs) are hereditary neurodegenerative disorders characterized by progressive declines in neurological functions, seizures, and premature death. NCLs result from mutations at least 13 different genes. Canine versions of the can serve as important models developing effective therapeutic interventions for these diseases. have been described a number dog breeds, including Chihuahuas. Studies were undertaken to further characterize pathology Chihuahua NCL...
CASE AND CONTEXT: This report describes a cat diagnosed with sinonasal-orbital Aspergillus fumigatus infection using advanced imaging, histopathology and culture. Aetiology, clinical aspects treatment of this rare devastating are discussed reference to literature review invasive mould (ie, filamentous fungal) infections involving tissues the naso-orbital region cats.
Purpose: To present case examples outlining the use of wavefront aberrometry for toric intraocular lens (IOL) implantation pre- and postoperatively. Methods: Twelve eyes that underwent AcrySof Toric IOL (Alcon Inc Laboratories) were assessed postoperatively using NIDEK OPD Scan II (NIDEK Co Ltd). Wavefront aberrometry, corneal topography, objective visual quality measured with OPD-Station software. The internal aberrations evaluated separately to determine whether source astigmatism was...
A metabolic study in a case of hyperornithinemia with gyrate atrophy choroid and retina is presented. It demonstrated that the lysine-ornithine antagonism physiological, safe, easy to handle therapeutic tool hyperornithinemia. lysine load was invariably associated reduction plasma ornithine concentration. This happened at any level protein intake. also shown diets containing low intake are negative nitrogen balance.
ABSTRACT PURPOSE: To discuss the use of wavefront measurements generated from NIDEK OPD-Scan Il and OPDStation for cataract surgery. METHODS: Case examples are presented along with information relevant clinical data obtained aberrometer OPD-Station software. All eyes underwent corneal topography, aberrometry, a uto refraction, keratometry, pupil lometry pre- postoperatively using OPDScan II. Optical visual quality simulations, including modulation transfer functions, attributable to internal...
Purpose: To present the use of point spread function (PSF) metric pre- and postoperatively for assessment visual quality in cataract refractive surgery. Methods: Case examples surgery effect accommodation are presented. All PSF measurements were obtained using NIDEK OPD-Scan II, corneal internal total aberrations simulated OPD-Station software. eyes underwent topography, wavefront aberrometry, autorefraction, keratometry, pupillometry OPDScan II. The was used to assess quality. Results: Four...
To describe a case of cat with primary B-cell lymphoma affecting the eye and brain which shared features similar to oculo-cerebral in humans.A 13-year-old castrated male Persian presented clinical signs anterior uveitis increased intraocular pressure (IOP) left (OS). A complete diagnostic work-up was declined, left-eye enucleation performed. The globe submitted for histopathology. One week after surgery, became inappetent, hypothermic, aggressive. Euthanasia requested by owner, necropsy...
5569 Background: Aim of this study was the clinical evaluation carboplatin-paclitaxel (Taxol) combination in a neoadjuvant and concomitant setting with conventional radiotherapy locoregionally advanced nasopharyngeal carcinoma (A-NPC) non endemic population. Methods: Thirty patients (22M, 8F, median age: 54 yrs, ECOG PS: 0; 27 pts type 3 2 WHO histology; 14 stage III, 13pts IVa IVb AJCC TNM; 21 N2/N3 TNM) were treated three cycles induction chemotherapy (IC) carboplatin (AUC6) plus...
Thirty-two patients (24 males, 8 females; median age 54 yrs) with recurrent and/or metastatic undifferentiated carcinoma of the nasopharyngeal type were treated chemotherapy. Remissions observed in 17 32 (53.2%) 5 complete (CR) (15.6%) and 12 partial responses (PR) (37.6%). A combination cisplatin 5-fluorouracil was most effective regimen (CR + PR = 83.3%). Objective responses. PR) 47% 11.7%) schemes without 60% 20%) cisplatin-based combinations. The overall duration response 7.2 months....