A5064466706- Innovative Microfluidic and Catalytic Techniques Innovation
- Chemical Synthesis and Analysis
- Analytical Chemistry and Chromatography
- Chemical Synthesis and Reactions
- Multicomponent Synthesis of Heterocycles
- Beetle Biology and Toxicology Studies
- Phenothiazines and Benzothiazines Synthesis and Activities
- Asymmetric Hydrogenation and Catalysis
- Cholinesterase and Neurodegenerative Diseases
- Synthesis and Catalytic Reactions
- Cannabis and Cannabinoid Research
- Various Chemistry Research Topics
- Microbial Natural Products and Biosynthesis
- Parkinson's Disease Mechanisms and Treatments
- Chemical synthesis and alkaloids
- Autophagy in Disease and Therapy
Xi’an Jiaotong-Liverpool University
2022-2024
University of Liverpool
2023-2024
Shenyang Pharmaceutical University
2021
Abstract Factors that might affect the removal time of high-boiling-point solvents with a rotary evaporator were examined. Considering several essential factors, optimized conditions for removing solvent are suggested. The results and discussion from this work can serve as reference current future organic chemists. Finally, two examples fast successful dehydration reactions given to demonstrate be used conduct syntheses.
Abstract Herein, we present a rapid and efficient method for synthesizing cyclic acetals ketals utilizing rotary evaporator. Unlike the conventional Dean–Stark dehydration process, which typically demands extended reaction times copious amounts of organic solvents, our approach affords synthesis with varying ring sizes in 30 min while using minimal quantities dimethyl sulfoxide as solvent. This innovative protocol features high yields, fast reactions, easy operation, broad substrate applicability.
Lemon juice has been studied and reported as an efficient catalyst or green medium in organic synthesis. The present digest paper shows the successful Removal of multiple acid-labile protecting groups using crude lemon for first time. Several drops can rapidly convert some simple liquid acetals to carbonyl compounds. Also, when mixed with ethanol, effectively removes cyclic other protection on primary secondary alcohols. In addition, selective acetonide diacetone-d-glucose its derivatives,...
Abstract A rapid benzylation of carboxylic acids was achieved under vacuum conditions and assisted by a rotary evaporator using p‐toluenesulfonic acid as catalyst. Unlike the conventional method that utilizes Dean‐Stark setup, which typically takes several hours or longer, completed in 30 minutes without solvent. Furthermore, this avoids BnBr acyl halide starting material generates water only byproduct. This protocol is featured its high yield, atom economy, fast reaction, broad substrate...
A new method was developed for the synthesis of Linezolid from commercially available (R)-3-(4-bromo-3-fluorophenyl)-5-(hydroxymethyl)oxazolidin-2-one. an antibiotic belongs to family oxazolidinones, it is successfully synthesized through a which include key step Buchwald-Hartwig amination reaction and Gabriel amine synthesis. The synthetic route easy perform with high yield. This provides huge possibility linezolid derivatives that may possibly tackle problem bacteria resistance oxazolidinones.