Ornella Xynomilakis

ORCID: 0009-0007-8190-1693
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Gut microbiota and health
  • Child Nutrition and Feeding Issues
  • Diet and metabolism studies
  • Gastrointestinal motility and disorders
  • Neuroscience and Neuropharmacology Research
  • Receptor Mechanisms and Signaling
  • Infant Health and Development
  • Celiac Disease Research and Management
  • Digestive system and related health
  • Pancreatic function and diabetes
  • Natural product bioactivities and synthesis
  • Infant Nutrition and Health
  • Bipolar Disorder and Treatment
  • Pharmacological Receptor Mechanisms and Effects
  • Cannabis and Cannabinoid Research
  • Nuts composition and effects
  • Breastfeeding Practices and Influences
  • Plant biochemistry and biosynthesis
  • GABA and Rice Research

University of Milan
2023-2025

University of Pisa
2023

The inhibitory effects of two novel lophine derivatives were unexpectedly discovered during the development a chemiluminescent monoacylglycerol lipase (MAGL) assay. proposed found to exhibit concentration-dependent on MAGL with octanoic and palmitic acid esters 2-(4-hydroxyphenyl)-4,5-diphenylimidazole showing strongest activity. Reversibility assays using fluorometric method confirmed that these compounds interact in stable, irreversible manner. To further investigate their mode...

10.3390/molecules30071605 article EN cc-by Molecules 2025-04-03

Breastfeeding is the gold standard in infant nutrition and continuous researches aim to optimize formula composition as best alternative available. Human milk lipid content provides more than 50% of energy requirements for infants together with essential vitamins, polyunsaturated fatty acids, other bioactive components. While acids vitamins human has been extensively studied and, when needed those have added formulas, less known about functional derivatives Here we describe comparison...

10.1016/j.jnutbio.2024.109580 article EN cc-by The Journal of Nutritional Biochemistry 2024-01-23

Abstract CDKL5 deficiency disorder (CDD) is a neurodevelopmental condition characterized by global developmental delay, early-onset seizures, intellectual disability, visual and motor impairments. Unlike Rett Syndrome (RTT), CDD lacks clear regression period. Patients with frequently encounter gastrointestinal (GI) disturbances exhibit signs of subclinical immune dysregulation. However, the underlying causes these conditions remain elusive. Emerging studies indicate potential connection...

10.1038/s41598-024-56989-0 article EN cc-by Scientific Reports 2024-03-28

ABSTRACT CDKL5 deficiency disorder (CDD) is a neurodevelopmental condition characterized by global developmental delay, early-onset seizures, intellectual disability, visual and motor impairments. Unlike Rett Syndrome (RTT), CDD lacks clear regression period. patients frequently encounter gastrointestinal (GI) disturbances exhibit signs of subclinical immune dysregulation. However, the underlying causes these conditions remain elusive. Emerging studies indicate potential connection between...

10.1101/2023.12.01.569361 preprint EN bioRxiv (Cold Spring Harbor Laboratory) 2023-12-03

Abstract CDKL5 deficiency disorder (CDD) is a neurodevelopmental condition characterized by global developmental delay, early-onset seizures, intellectual disability, visual and motor impairments. Unlike Rett Syndrome (RTT), CDD lacks clear regression period. patients frequently encounter gastrointestinal (GI) disturbances exhibit signs of subclinical immune dysregulation. However, the underlying causes these conditions remain elusive. Emerging studies indicate potential connection between...

10.21203/rs.3.rs-3691378/v1 preprint EN cc-by Research Square (Research Square) 2023-12-07
Coming Soon ...