A5034122039- Karst Systems and Hydrogeology
- Circadian rhythm and melatonin
- Gut microbiota and health
- Diet and metabolism studies
- Geology and Paleoclimatology Research
- Tryptophan and brain disorders
- Adipose Tissue and Metabolism
- Epigenetics and DNA Methylation
- Neuroscience and Neuropharmacology Research
- Genetics and Neurodevelopmental Disorders
- Landslides and related hazards
- MicroRNA in disease regulation
- Neural dynamics and brain function
- Gastrointestinal motility and disorders
- Dietary Effects on Health
- Circular RNAs in diseases
- Neuropeptides and Animal Physiology
- Genetics, Aging, and Longevity in Model Organisms
- Diet, Metabolism, and Disease
- RNA Research and Splicing
- Geological Formations and Processes Exploration
- Cancer-related molecular mechanisms research
- Neurogenesis and neuroplasticity mechanisms
- Spaceflight effects on biology
- Child Nutrition and Feeding Issues
University of Pisa
2020-2024
Scuola Superiore Sant'Anna
2024
University of California, Irvine
2015-2024
Scuola Normale Superiore
2011-2023
Lombardia Informatica (Italy)
2020
Neuroscience Institute
2011-2016
National Research Council
2016
University of Milan
2000-2014
Istituto di Scienza e Tecnologie dell'Informazione "Alessandro Faedo"
2011
National Academies of Sciences, Engineering, and Medicine
2008
Perineuronal nets (PNNs) surround specific neurons in the brain and are involved various forms of plasticity clinical conditions. However, our understanding PNN role these phenomena is limited by lack highly quantitative maps distribution association with cell types. Here, we present a comprehensive atlas Wisteria floribunda agglutinin (WFA)-positive PNNs colocalization parvalbumin (PV) cells for over 600 regions adult mouse brain. Data analysis shows that PV expression good predictor...
Exposing animals to an enriched environment (EE) has dramatic effects on brain structure, function, and plasticity. The poorly known "EE-derived signals'' mediating the EE are thought be generated within central nervous system. Here, we shift focus body periphery, revealing that gut microbiota signals crucial for EE-driven Developmental analysis reveals striking differences in intestinal bacteria composition between standard rearing (ST) mice, as well enhanced levels of short-chain fatty...
Significance Nutrition and the body clock are deeply intertwined, both impinging on our physiological health. Food composition can dramatically rewire peripheral metabolism; however, whether food challenges impact circadian metabolism of master in suprachiasmatic nucleus (SCN) or other brain areas has not been fully explored. Here we analyzed complete diurnal metabolome SCN medial prefrontal cortex (mPFC) mice fed a balanced diet high-fat (HFD). Strikingly, data reveal unexpected daily...
Morgana Cave is located in Val di Scerscen , Central Italian Alps. The cave opens at an altitude of 2,600 m a.s.l. close to the retreating glacier Vedretto and its entrance was discovered 30 years ago hidden underneath glacier. A characteristic this occurrence vermiculation deposits on walls ceiling. In general, composition microbial communities vermiculations relatively unknown rarely investigated. Here we present data a geomicrobiological study from Alpine subjected extreme climate...
Progress in the understanding of cave genesis processes, as well intensive research carried out Alps during last decades, permit to summarize latest knowledge about Alpine caves. The phreatic parts systems develop close karst water table, which depends on spring position, turn is generally related valley bottom. Thus, caves are directly linked with geomorphic evolution surface and reflect deepening. sediments deposited help reconstruct morphologic succession paleoclimatic evolution....
Loss of visual acuity caused by abnormal experience during development (amblyopia) is an untreatable pathology in adults. In some occasions, amblyopic patients loose vision their better eye owing to accidents or illnesses. While this condition relevant both for its clinical importance and because it represents a case which binocular interactions the cortex are suppressed, has scarcely been studied animal models. We investigated whether exposure environmental enrichment (EE) effective...
Abstract MicroRNAs (miRNAs) are known to mediate post-transcriptional gene regulation, but their role in postnatal brain development is still poorly explored. We show that the expression of many miRNAs dramatically regulated during functional maturation mouse visual cortex with miR-132/212 family being one top upregulated miRNAs. Age-downregulated transcripts significantly enriched miR-132/miR-212 putative targets and genes null mice. At a level, deletion affects receptive fields cortical...