A5102127146- Neuroinflammation and Neurodegeneration Mechanisms
- Hydrocarbon exploration and reservoir analysis
- Parkinson's Disease Mechanisms and Treatments
- Geological and Geophysical Studies
- Neurological Disease Mechanisms and Treatments
- Anomaly Detection Techniques and Applications
- Paleontology and Stratigraphy of Fossils
- Geochemistry and Elemental Analysis
- Geological and Geochemical Analysis
- Video Surveillance and Tracking Methods
- Receptor Mechanisms and Signaling
- Immune Response and Inflammation
- Circular RNAs in diseases
- Geological Studies and Exploration
- Sparse and Compressive Sensing Techniques
- Cancer-related molecular mechanisms research
- Histone Deacetylase Inhibitors Research
- Barrier Structure and Function Studies
- Distributed Control Multi-Agent Systems
- Methane Hydrates and Related Phenomena
- Autophagy in Disease and Therapy
- Geology and Paleoclimatology Research
- Human Pose and Action Recognition
- Neuroscience and Neuropharmacology Research
- Traditional Chinese Medicine Analysis
Anhui University of Traditional Chinese Medicine
2024-2025
Shandong University
2015-2024
China University of Geosciences
2007-2024
Sinopec (China)
2014-2024
Shandong Provincial Hospital
2019-2024
University of Utah
2021-2022
China Geological Survey
2019-2022
Suzhou Municipal Hospital
2022
Jinan Central Hospital
2021
Institute of Geology and Geophysics
2012
Research Article| December 01, 2007 Changes in the global carbon cycle occurred as two episodes during Permian–Triassic crisis Shucheng Xie; Xie 1Key Laboratory of Biogeology and Environmental Geology Ministry Education, State Key Geological Processes Mineral Resources, China University Geosciences, Wuhan 430074, People's Republic Search for other works by this author on: GSW Google Scholar Richard D. Pancost; Pancost 2Bristol Biogeochemistry Center, School Chemistry, Bristol, Cantock's...
Background: Increasing evidences suggest that innate immunity is involved in cerebral ischemia-reperfusion (I/R) injury, but the liable immune receptors have not been completely elucidated.Here, we explored role of nucleotide-binding oligomerization domain (NOD)2, a member cytosolic NOD-like receptor family, acute focal I/R injury.Methods: An vivo middle artery occlusion (MCAO) model wild type (WT) and NOD2 deficient (NOD2 -/ -) mice vitro oxygen glucose deprivation reoxygenation (OGD/R)...
Tripartite motif (TRIM) 31 has been implicated in diverse biological and pathological conditions. However, whether TRIM31 plays a role ischemic stroke progression is not clarified. Here we demonstrated that was significantly downregulated the brain deficiency of alleviated injury induced by middle cerebral artery occlusion reducing reactive oxygen species production maintaining mitochondrial homeostasis. Mechanistically, found an E3 ubiquitin ligase for TP53-induced glycolysis apoptosis...
G protein-coupled receptor 120 (GPR120) has been shown to negatively regulate inflammation and apoptosis, but its role in cerebral ischemic injury remains unclear. Using an vivo model of middle artery occlusion (MCAO) vitro oxygen-glucose deprivation (OGD), we investigated the potential molecular mechanisms GPR120 focal injury. Increased expression was observed microglia neurons following MCAO-induced ischemia wild type C57BL/6 mice. Treatment with docosahexaenoic acid (DHA) inhibited...
We aimed to analyze the clinical features, treatment, and prognosis of Wilson disease (WD) combined with polycystic ovary syndrome (PCOS), explore correlation between endocrine abnormalities liver damage. The data 40 female patients WD PCOS (PCOS-WD) were retrospectively analyzed. 43 age- BMI-matched non-WD (PCOS-NWD) performed as control group. PCOS-WD assigned adolescent group (n = 18) reproductive age 22) according onset PCOS, also normal testosterone elevated level. laboratory tests,...
In Parkinson's disease (PD), loss of striatal dopaminergic (DA) terminals and degeneration DA neurons in the substantia nigra (SN) are associated with inflammation. Nucleotide-binding oligomerization domain-containing protein (NOD)2, one first discovered NOD-like receptors, plays an important role However, NOD2 has not been elucidated PD.NOD2 mRNA expression SN striatum C57BL/6 mice treated 6-hydroxydopamine (6-OHDA) was measured. We next investigated potential contribution NOD2-dependent...
Abstract We previously reported that nucleotide‐binding oligomerization domain‐containing protein ( NOD ) 2 was involved in the inflammatory responses to cerebral ischaemia/reperfusion (I/R) insult. However, mechanism by which participates brain ischaemic injury and regulation of process are still obscure. Increased β‐arrestin ARRB 2) expression observed microglia following I/R wild‐type mice besides up‐regulation TRAF 6. Stimulation muramyl dipeptide MDP BV cells induced activation NF ‐κB...
Although it is established that opioid and Mycobacterium tuberculosis are both public health problems, the mechanisms by which they affect lung functions remain elusive.We report here mice subjected to chronic morphine administration M. infection exhibited significant apoptosis in wild type as demonstrated terminal deoxynucleotidyl transferase-mediated deoxyuridine triphosphate nick end labeling assay. Morphine significantly induced expression of Toll-like receptor 9 (TLR9), a key mediator...
BackgroundAntrochoanal polyp (ACP) is a benign nasal mass of unknown etiology. Tight junctions (TJs) are essential to the epithelial barrier that protects body from external damage. However, phenotype tight junction in ACP currently unclear.MethodsThe samples were collected 20 controls, 37 patients with and 45 chronic rhinosinusitis (CRSwNP). Quantitative Real-Time PCR (qRT-PCR) immunofluorescence staining (IF) performed analyze expressions TJs markers (ZO-1, claudin-3 occludin) ZEB1. hNEpCs...