- Antibiotic Use and Resistance
- Antimicrobial Resistance in Staphylococcus
- Bacterial Identification and Susceptibility Testing
- Orthopedic Infections and Treatments
- Hydrogen's biological and therapeutic effects
- Genetic Associations and Epidemiology
- Bone health and treatments
- Ferroptosis and cancer prognosis
- Cancer Immunotherapy and Biomarkers
- Mycotoxins in Agriculture and Food
- melanin and skin pigmentation
- Nosocomial Infections in ICU
- Bone and Joint Diseases
- Galectins and Cancer Biology
First Affiliated Hospital of Fujian Medical University
2023
Fujian Medical University
2023
First Affiliated Hospital of Zhengzhou University
2023
First Affiliated Hospital of Nanchang University
2019-2021
Nanchang University
2019-2021
Acute ischemic stroke poses major challenges due to high disability and mortality rates. Ferroptosis, a form of regulated cell death triggered by iron-induced oxidative stress, plays key role in injury. Despite its long history treatment, the mechanism Buyang Huanwu Decoction (BHD) ferroptosis remains unclear. Network pharmacology predicted BHD's active components pathways, while Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS) confirmed main ingredients. Middle...
Abstract Background Hospital-acquired infections (HAIs) are an emerging global problem that increases in-hospital mortality, length of stay, and cost. We performed a 6-year retrospective study to provide valuable insight into appropriate antibiotic use in HAI cases. also aimed understand how hospitals could reduce pathogen drug resistance population overuses antibiotics. Methods All data (2012–2017) were obtained from the hospital information warehouse clinical microbiology laboratory....
The correlation between peripheral blood neutrophil level and osteonecrosis of the femoral head (ONFH) has not been extensively studied. Thus, we aimed to investigate in (neutrophil granulocyte) ONFH. A total 984 cases ONFH neck fractures (non-ONFH) diagnosed at Department Orthopedics our institution January 1, 2011 December 31, 2016 were retrospectively reviewed. non-ONFH groups comprised 488 496 cases, respectively. Basic information cell levels two compared. patients' mean age was 59.89 ±...
To investigate the causal relationship between poor lifestyle habits, such as smoking and drinking, cutaneous malignant melanoma. In present study, alcohol consumption were used exposure factors, single nucleotide polymorphisms closely associated with instrumental variables, while melanoma was set an outcome variable. Two-sample Mendelian randomization analyses run to their associations, respectively. We found a positive statistically significant effect of intake on risk (OR: 2.23; 95%CI:...
Abstract Background Infiltration of CD8 + T cells in the tumor microenvironment is correlated with better prognosis various malignancies. Our study aimed to investigate vital genes cell infiltration stomach adenocarcinoma (STAD) and develop a new prognostic model. Methods Using STAD dataset, differentially expressed (DEGs) were analyzed, co-expression networks constructed. Combined CIBERSORT algorithm, most relevant module WGCNA was selected for subsequent analysis. The screened out by...
Abstract Background: Hospital-acquired infections (HAIs) are an emerging global problem that increases in-hospital mortality, length of stay, and cost. We performed a 6-year retrospective study to provide valuable insight into appropriate antibiotic use in HAI cases. also aimed understand how hospitals could reduce pathogen drug resistance population overuses antibiotics. Methods: All data (2012–2017) were obtained from the Hospital Information Warehouse Clinical Microbiology Laboratory....
Abstract Background Hospital-acquired infections (HAIs) are an emerging global problem that increases in-hospital mortality, length of stay, and cost. Orthopedics departments experience a particularly high infection rate, partially due to their heavy reliance on invasive medical devices. We performed 6-year retrospective study provide valuable insight into appropriate antibiotic use in HAI cases. also aimed understand how hospitals could reduce pathogen drug resistance population overuses...