Jiaxiang Xu

ORCID: 0009-0007-9576-8416
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About
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Research Areas
  • Antibiotic Use and Resistance
  • Antimicrobial Resistance in Staphylococcus
  • Bacterial Identification and Susceptibility Testing
  • Orthopedic Infections and Treatments
  • Hydrogen's biological and therapeutic effects
  • Genetic Associations and Epidemiology
  • Bone health and treatments
  • Ferroptosis and cancer prognosis
  • Cancer Immunotherapy and Biomarkers
  • Mycotoxins in Agriculture and Food
  • melanin and skin pigmentation
  • Nosocomial Infections in ICU
  • Bone and Joint Diseases
  • Galectins and Cancer Biology

First Affiliated Hospital of Fujian Medical University
2023

Fujian Medical University
2023

First Affiliated Hospital of Zhengzhou University
2023

First Affiliated Hospital of Nanchang University
2019-2021

Nanchang University
2019-2021

Acute ischemic stroke poses major challenges due to high disability and mortality rates. Ferroptosis, a form of regulated cell death triggered by iron-induced oxidative stress, plays key role in injury. Despite its long history treatment, the mechanism Buyang Huanwu Decoction (BHD) ferroptosis remains unclear. Network pharmacology predicted BHD's active components pathways, while Ultra Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS) confirmed main ingredients. Middle...

10.2147/dddt.s503424 article EN cc-by-nc Drug Design Development and Therapy 2025-03-01

Abstract Background Hospital-acquired infections (HAIs) are an emerging global problem that increases in-hospital mortality, length of stay, and cost. We performed a 6-year retrospective study to provide valuable insight into appropriate antibiotic use in HAI cases. also aimed understand how hospitals could reduce pathogen drug resistance population overuses antibiotics. Methods All data (2012–2017) were obtained from the hospital information warehouse clinical microbiology laboratory....

10.1186/s13018-021-02234-7 article EN cc-by Journal of Orthopaedic Surgery and Research 2021-02-01

The correlation between peripheral blood neutrophil level and osteonecrosis of the femoral head (ONFH) has not been extensively studied. Thus, we aimed to investigate in (neutrophil granulocyte) ONFH. A total 984 cases ONFH neck fractures (non-ONFH) diagnosed at Department Orthopedics our institution January 1, 2011 December 31, 2016 were retrospectively reviewed. non-ONFH groups comprised 488 496 cases, respectively. Basic information cell levels two compared. patients' mean age was 59.89 ±...

10.1186/s12891-019-2778-7 article EN cc-by BMC Musculoskeletal Disorders 2019-08-31

To investigate the causal relationship between poor lifestyle habits, such as smoking and drinking, cutaneous malignant melanoma. In present study, alcohol consumption were used exposure factors, single nucleotide polymorphisms closely associated with instrumental variables, while melanoma was set an outcome variable. Two-sample Mendelian randomization analyses run to their associations, respectively. We found a positive statistically significant effect of intake on risk (OR: 2.23; 95%CI:...

10.1016/j.gaceta.2023.102351 article ES cc-by-nc-nd Gaceta Sanitaria 2023-01-01

Abstract Background Infiltration of CD8 + T cells in the tumor microenvironment is correlated with better prognosis various malignancies. Our study aimed to investigate vital genes cell infiltration stomach adenocarcinoma (STAD) and develop a new prognostic model. Methods Using STAD dataset, differentially expressed (DEGs) were analyzed, co-expression networks constructed. Combined CIBERSORT algorithm, most relevant module WGCNA was selected for subsequent analysis. The screened out by...

10.1186/s12876-023-03003-y article EN cc-by BMC Gastroenterology 2023-11-17

Abstract Background: Hospital-acquired infections (HAIs) are an emerging global problem that increases in-hospital mortality, length of stay, and cost. We performed a 6-year retrospective study to provide valuable insight into appropriate antibiotic use in HAI cases. also aimed understand how hospitals could reduce pathogen drug resistance population overuses antibiotics. Methods: All data (2012–2017) were obtained from the Hospital Information Warehouse Clinical Microbiology Laboratory....

10.21203/rs.3.rs-103706/v1 preprint EN cc-by Research Square (Research Square) 2020-11-17

Abstract Background Hospital-acquired infections (HAIs) are an emerging global problem that increases in-hospital mortality, length of stay, and cost. Orthopedics departments experience a particularly high infection rate, partially due to their heavy reliance on invasive medical devices. We performed 6-year retrospective study provide valuable insight into appropriate antibiotic use in HAI cases. also aimed understand how hospitals could reduce pathogen drug resistance population overuses...

10.21203/rs.2.9477/v1 preprint EN cc-by Research Square (Research Square) 2019-05-07
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