Abstract Patients infected with multidrug-resistant organisms (MDROs) are known to exhibit longer hospital stays and a significantly poorer prognosis. We performed 6-year retrospective analysis of nosocomial infections reported in the orthopedics department our institution, gain valuable insights into antibiotic sensitivity infectious characteristics MDROs, order deduce effective measures control occurrence clinical practice. A retrospective, single center surveillance study (January...

Currently, many scholars are concerned about the treatment of postoperative infection; however, few have completed multivariate analyses to determine factors that contribute risk infection. Therefore, we conducted a analysis retrospectively collected database analyze for acute surgical site infection following lumbar surgery, including fracture fixation, fusion, and minimally invasive surgery. We reviewed data from patients who underwent surgery between 2014 2016, internal in our hospital's...

The aim of this study was to investigate the correlation between facet tropism and spinal degenerative diseases, such as lumbar spondylolisthesis, scoliosis, disc herniation. This retrospectively analysed clinical data from Department Orthopaedics at First Affiliated Hospital Nanchang University. Ninety-two patients were diagnosed with 64 86 herniation 1 October 2014 2016. All using 3.0 T magnetic resonance imaging underwent conservative or operative treatment. Facet defined greater than a...

Background Aedes albopictus is a major vector for several tropical infectious diseases. Characterization of Ae. development under natural conditions crucial monitoring population expansion, dengue virus transmission, and disease outbreak preparedness. Methods This study employed mosquito traits as proxy to understanding life-table in mosquitoes using semi–field study. larval adult experiments were conducted microcosms semi-field Guangzhou. Stage-specific times survivorship rates determined...

Pain and disability associated with degenerative lumbar spondylolisthesis (DLS) results in significant burden on both the patients' quality of life healthcare costs. Currently, there is controversy regarding specificity spinopelvic measures sagittal plane alignment respect to DLS. Moreover, correlation among parameters remains be clarified. Our aim this study was compare these measurements between patients single-segment DLS at L5 a control group no history formed 132 who underwent full...

Abstract Lumbar 3-joint complex degeneration is a multifactorial, pathological process. Previous studies included insufficient quantitative analyses to prove the relationship between disc and facet joint osteoarthritis (OA). We assessed correlation intervertebral lumbar using computed tomography (CT) magnetic resonance imaging (MRI) parameters. A total of 152 participants who underwent conventional MRI CT in clinostat position were this study. The presence was identified Pfirrmann grading...

Aminoacyl-tRNA synthetases (aaRSs) are essential enzymes in translation by linking amino acids onto their cognate tRNAs during protein synthesis. During evolution, aaRSs develop numerous non-canonical functions that expand the roles of eukaryotic organisms. Although have been implicated viral infection, function infections with coronaviruses (CoVs) remains unclear. Here, we analyzed data from transcriptomic and proteomic database on human cytoplasmic (cyto) mitochondrial (mt) across three...

Abstract Background Hospital-acquired infections (HAIs) are an emerging global problem that increases in-hospital mortality, length of stay, and cost. We performed a 6-year retrospective study to provide valuable insight into appropriate antibiotic use in HAI cases. also aimed understand how hospitals could reduce pathogen drug resistance population overuses antibiotics. Methods All data (2012–2017) were obtained from the hospital information warehouse clinical microbiology laboratory....

A rapidly aging society and longer life expectancy are causing osteoporosis to become a global epidemic. Over the last five decades, number of drugs aimed at reducing bone resorption or restoring mass have been developed, but their efficacy safety limited. Icaritin (ICT) is natural compound extracted from anti-osteoporosis herb Epimedium spp. has shown inhibit osteoclast differentiation. However, molecular mechanism by which ICT weaken RANKL-induced differentiation not completely...

Aluminum (Al) toxicity in acid soils is a significant limitation to crop production worldwide, as 13% of the world's rice produced soil with high Al content. Rice likely most Al-resistant cereal and also cereal, where resistance genetically complex external detoxification internal tolerance. Many Al-resistance genes have been cloned, including transcription factor 1 (ART1) other factors, organic transporter genes, metal ion gene. This review summarized recent characterized affecting...

Anthropogenic climate change is challenging biodiversity conservation worldwide. Climate metrics derived from future predictions help to assess potential impacts of on biodiversity. Here we calculated velocities across biogeographical regions terrestrial Europe and the Natura 2000 protected area network, largest network Earth. We applied projections for year 2070, considering two emission scenarios, six global models a fine spatial resolution. Areas with very high velocity were identified as...

The systems of alkali metal atom doped boron have been investigative topics over the years because their diverse configurations and unique properties. Based on this, with assistance CALYPSO software facilitates structure prediction process, our group went into geometric structures bonding characteristics NaBn (n = 1–12) clusters. From structural analysis, participation Na does not dramatically change clusters, clusters maintain parallel planar configuration evolution model pure local most...

This study investigated greenhouse gas (GHG) emission characteristics of lactating Holstein dairy cows in East China and provided a basis for formulating GHG reduction measures. GreenFeed system was used to measure the amount methane (CH4) carbon dioxide (CO2) emitted by through respiration. Data from commercial cow farm were observe effects parity, body weight, milk yield, component yield on CH4 CO2 emissions.Mean herd responses throughout as follows: 111 completed all experimental...

Abstract Objective This research studied the in vivo motion characteristics of L3–S1 lumbar spine with facet-joint degeneration during functional activities. Methods Thirteen male and 21 female patients at spinal region were included study. The segments all divided into 3 groups according to degree facet-joints (mild, moderate, or severe). ranges (ROM) vertebrae analyzed using a combination computed tomography dual fluoroscopic imaging techniques. During postures, ROMs compared between each...

Background: Infection, including mixed infection, is not uncommon in orthopedic surgical incision. This study aimed to investigate the epidemiology and drug resistance of infections after procedures. Methods: We retrospectively analyzed 533 site (SSIs) a university hospital from 2012 2017. Eighty-six patients (218 strains) with bacterial culture results showing more than one strain were screened explore their resistance. Results: Of 218 strains, 2–7 noted each wound. Most caused by two kinds...

Cryptococcal spine infections are rare that easy to misdiagnose and difficult cure. Therefore, we report the case of a 25-year-old man who presented with nonspecific spinal lesions at L1 S1. The patient underwent surgical removal lesions, specimens were submitted for microbial identification, which identified cryptococcal infection was susceptible amphotericin B. exhibited marked improvement after receiving intravenous B remained asymptomatic (no back pain, fever, or other symptoms) 3‑...

Osteoporosis (OP) is a systemic metabolic orthopedic disorder prevalent in elderly people, that characterized by decrease bone mass. Although many therapeutics have been adopted for OP treatment, of them are still not well satisfied clinical requirements and therefore development novel great significance. In this work, bone-targeting drug self-frame delivery system (DSFDS) with high loading efficiency pH responsive release was fabricated condensation curcumin (Cur), amino group terminated...

<b><i>Introduction:</i></b> Women with epilepsy (WWE) are more likely to develop reproductive endocrine disorders, especially polycystic ovary syndrome (PCOS). This study aimed explore the genetic factors of PCOS in WWE hope improving individual precision diagnosis and treatment. <b><i>Methods:</i></b> registered at West China Hospital between January 2022 October were enrolled this study. Demographic epilepsy-related characteristics recorded,...

Osteoarthritis research has been most commonly performed in the setting of articular cartilage knee. To best our knowledge, no studies have evaluated role adiponectin osteoarthritis lumbar facet joint (FJOA). Therefore, this study, we explored whether was expressed joints and FJOA.We enrolled patients who underwent computed tomography (CT) magnetic resonance imaging (MRI) at Orthopedic Department First Affiliated Hospital Nanchang from May 2015 to June 2016. Lumbar were obtained 135 time...

In semantic segmentation, accurate prediction masks are crucial for downstream tasks such as medical image analysis and editing. Due to the lack of annotated data, few-shot segmentation (FSS) performs poorly in predicting with precise contours. Recently, we have noticed that large foundation model segment anything (SAM) well processing detailed features. Inspired by SAM, propose FSS-SAM boost FSS methods addressing issue inaccurate contour. The is training-free. It works a post-processing...

We report a newborn girl with large purplish swelling on her right arm. The diagnosis was established imaging and biopsy of the lesion.