A5026847483- Bone Metabolism and Diseases
- Orthodontics and Dentofacial Orthopedics
- Seaweed-derived Bioactive Compounds
- Dental Anxiety and Anesthesia Techniques
- Bone Tissue Engineering Materials
- Seed Germination and Physiology
- Autism Spectrum Disorder Research
- Dental Implant Techniques and Outcomes
- Cytokine Signaling Pathways and Interactions
- Gout, Hyperuricemia, Uric Acid
- CRISPR and Genetic Engineering
- Renal cell carcinoma treatment
- Parkinson's Disease Mechanisms and Treatments
- Dental Health and Care Utilization
- Orthopaedic implants and arthroplasty
- Temporomandibular Joint Disorders
- Marine Sponges and Natural Products
- Estrogen and related hormone effects
- Biochemical effects in animals
- Plant Genetic and Mutation Studies
- Nuclear Receptors and Signaling
- BRCA gene mutations in cancer
- Medicinal plant effects and applications
- Plant Molecular Biology Research
- Immune Response and Inflammation
Wonkwang University
2014-2023
Chungnam National University
2023
Neurological Research Institute
2018
Texas Children's Hospital
2018
Baylor College of Medicine
2018
Korea Institute of Science & Technology Information
2014
Jeju National University
2014
Korea Advanced Institute of Science and Technology
2009
Yonsei University
2001
Abstract PHYTOCHROME INTERACTING FACTOR 3-LIKE5 (PIL5) is a basic helix-loop-helix transcription factor that inhibits seed germination by regulating the expression of gibberellin (GA)- and abscisic acid (ABA)-related genes either directly or indirectly. It not yet known, however, whether PIL5 regulates solely through GA ABA. Here, we used Chromatin immunoprecipitation-chip (ChIP-chip) analysis to identify 748 novel binding sites in Arabidopsis thaliana genome. Consistent with molecular...
Fucoidan has attracted attention as a potential drug because of its biological activities, which include osteogenesis. However, the molecular mechanisms involved in osteogenic activity fucoidan human alveolar bone marrow-derived mesenchymal stem cells (hABM-MSCs) remain largely unknown. We investigated action on osteoblast differentiation hABM-MSCs and impact signaling pathways. Its effect proliferation was determined using crystal violet staining assay. Osteoblast evaluated based alkaline...
Accumulation of α-Synuclein (α-Syn) causes Parkinson's disease (PD) as well other synucleopathies. α-Syn is the major component Lewy bodies and neurites, proteinaceous aggregates that are a hallmark sporadic PD. In familial forms PD, mutations or copy number variations in SNCA (the gene) result net increase its protein levels. Furthermore, common risk variants tied to PD associated with small increases wild-type These findings further bolstered by animal studies which show overexpression...
Inflammatory chemokines, such as macrophage-derived chemokine (MDC/CCL22), are elevated in the serum and lesioned skin of patients with atopic dermatitis (AD), ligands for C-C receptor 4, which is predominantly expressed on T helper 2 lymphocytes, basophils natural killer cells. We have previously reported that quercetagetin has an inhibitory activity inflammatory induced by interferon (IFN)-γ tumour necrosis factor (TNF)-α, occurring via inhibition signal transducer activator transcription...
Background: Mesenchymal stem cells (MSCs) are pluripotent stromal that among the most appealing candidates for regenerative medicine and may aid in repair regeneration of skeletal disorders through multiple mechanisms, including angiogenesis, differentiation, response to inflammatory conditions. Tauroursodeoxycholic acid (TUDCA) has recently been used various cell types as one these drugs. The mechanism osteogenic differentiation by TUDCA hMSCs remains unknown. Methods: Cell proliferation...
Abstract Background Whitlockite (WH; Ca 18 Mg 2 (HPO 4 ) (PO 12 as the second most abundant ceramic of human bone after hydroxyapatite (HA; 10 6 (OH) ), possessing high osteogenic activity, has been known that it can stimulate differentiation well suppress osteoclastic particularly, in preparatory stage regeneration. Methods In this work, we construct a unique structure by layering WH on surface HA granules (HAGs)s via dip-coating and sintering method. Results The cell proliferation...
Currently, dental implants have become predictable and reliable adjuncts for oral rehabilitation. Osseointegrated can be used to provide rigid orthodontic anchorage advantages compared conventional especially when there were edentulous areas scheduled as a treatment plan. Orthodontic force doesn't cause the bone loss of osseointegrated implants. Implant materials, surgical protocols healing time before loading follow protocol. Because implants, once installed, can't change location,...
Background: This study aimed to evaluate the effect of a prefabricated functional appliance (Myobrace Ⓡ ) on skeletal, dental, and soft tissue components in children with Class II, division 1 malocclusion.Methods: Thirteen patients malocclusion (9 girls 4 boys; mean age, 8.2±0.9 years at start 9.3±1.0 end treatment) were treated Myobrace for period 12.9±4.0months.Patients instructed use daily hour overnight while sleeping.A control group 10 untreated (3 7 9.0±1.6 10.4±2.1 observation) was...
Background: This study aimed to determine the skeletal and dental effects in pediatric adolescent Korean patients with Class II Division 1 malocclusion treated using Invisalign Mandibular Advancement (MA Ⓡ ) appliance.Methods: The included aged 6 18 years who received orthodontic treatment MA appliance for at Department of Pediatric Dentistry, Wonkwnag University Daejeon Dental Hospital, between July 1, 2018, December 31, 2021.The group consisted 20 patients, 10 boys girls.The control...