G Shen

ORCID: 0009-0007-9653-5817
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About
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Research Areas
  • MicroRNA in disease regulation
  • Wound Healing and Treatments
  • Extracellular vesicles in disease
  • Child Nutrition and Water Access
  • RNA modifications and cancer
  • Mesenchymal stem cell research
  • Colorectal Cancer Screening and Detection
  • Colorectal Cancer Surgical Treatments
  • Genetic factors in colorectal cancer
  • Cancer-related molecular mechanisms research
  • Health, Environment, Cognitive Aging

Soochow University
2024

First Affiliated Hospital of Soochow University
2024

Air Force Medical University
2014

Cancer Institute (WIA)
1998

Dysregulation of transcription factors (TFs) is associated with tumor progression, but little known about TF expression patterns in the context gastric cancer (GC) metastasis. Using array-based profile analysis, we found that 22 TFs showed differential activities between GC cell lines low- and high-metastatic potential. Of this group TFs, serum response factor (SRF) was significantly upregulated metastatic cells. SRF frequently elevated a panel cells tissues, high-level more aggressive...

10.1038/cdd.2014.109 article EN cc-by-nc-nd Cell Death and Differentiation 2014-08-01

Background: Colorectal cancer is the third most common in world, arising mostly from pre-existing adenomatous polyps (adenomas) of large bowel. Patients with colorectal adenomas are at increased risk because a high recurrence rate for adenomas. We followed cohort 1490 patients rectal to determine whether might be related pathologic characteristics initial Methods: The were identified Haining County, China, 1977 through 1978 by means examination 15-cm rigid sigmoidoscope. They endoscopic...

10.1093/jnci/90.21.1661 article EN JNCI Journal of the National Cancer Institute 1998-11-04

Abstract Background Adipose‐derived stem cells (ADSCs) hold promising application prospects in the treatment of diabetic wounds, although underlying mechanisms repair have not been fully elucidated. This research aimed to elucidate by which ADSCs promote wound healing. Methods Exosomes from were isolated and circRps5 level was identified. To investigate role regulation, exosomes differently treated used. Different injected into edge mice, effects on healing status, pathology, collagen,...

10.1002/iid3.1274 article EN cc-by Immunity Inflammation and Disease 2024-06-01
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