A5103141775- Enzyme Catalysis and Immobilization
- Electrochemical sensors and biosensors
- Advanced Nanomaterials in Catalysis
- Nanomaterials for catalytic reactions
- Microbial Metabolic Engineering and Bioproduction
- Metal-Organic Frameworks: Synthesis and Applications
- Mesoporous Materials and Catalysis
- Asymmetric Hydrogenation and Catalysis
- Advanced biosensing and bioanalysis techniques
- Catalysis for Biomass Conversion
- Innovative Microfluidic and Catalytic Techniques Innovation
- Advanced Photocatalysis Techniques
- Enzyme-mediated dye degradation
- Graphene and Nanomaterials Applications
- Biodiesel Production and Applications
- Electrochemical Analysis and Applications
- Chemical Synthesis and Analysis
- Algal biology and biofuel production
- Biofuel production and bioconversion
- Polymer Surface Interaction Studies
- Covalent Organic Framework Applications
- Analytical Chemistry and Chromatography
- MXene and MAX Phase Materials
- Pickering emulsions and particle stabilization
- CO2 Reduction Techniques and Catalysts
Hebei University of Technology
2016-2025
Guangxi University
2025
Qingdao University
2025
Hainan Medical University
2022-2024
Hainan General Hospital
2022-2024
Wenzhou Medical University
2023-2024
Zhejiang Lab
2023-2024
Changchun University of Chinese Medicine
2024
Qingdao University of Science and Technology
2010-2017
University of Benin
2016
Photocatalytic regeneration of a nicotinamide cofactor, adenine dinucleotide phosphate (NADPH), has emerged as an ideal cascade partner for combination with enzymatic transformations, but it still suffers from low efficiency due to the recombination photogenerated charge carriers. Herein, hierarchical Rh-covalent organic framework (COF)@COF core–shell hollow sphere (CSHS) S-scheme heterojunction is proposed enhance carrier transfer and utilization in photocatalysis regenerate expensive...
A nano-form composite of MXenes (Ti3C2Tx, Tx = -O, -OH, -F) was synthesized through depositing bismuth-nanoparticle (BiNPs) onto Ti3C2Tx sheets. Because the preventive effect two-dimensional layered structure Ti3C2Tx, nanoparticles Bi were uniform and well attached on Ti3C2Tx. The obtained BiNPs/Ti3C2Tx nano-composite applied for sensors construction electrochemical detecting Pb2+ Cd2+ heavy metal ions. produced BiNPs@Ti3C2Tx-based sensor showed high effective surface area excellent...
A controllable and facile strategy is established for constructing metal-organic frameworks-based (MOF-based) hollow composites via a protein-induced soft-templating pathway. Using metal-sodium deoxycholate hydrogel as soft-template, nanotubes are gained while the protein absent. With presence of protein, nanospheres structure prepared by changing amount protein. To verify universality proposed pathway, two kinds proteins (
A simple and efficient strategy was developed to synthesize polyacrylonitrile-copper oxide (PAN-CuO) nanoflowers by growing copper nanoneedles on the surface of polyacrylonitrile (PAN) under mild conditions. Fortunately, obtained PAN-CuO exhibit excellent peroxidase-mimicking activity catalyze oxidation 3,3′,5,5′-tetramethylbenzidine (TMB) form a blue-colored solution with H2O2. The peroxidase-like mechanism originated from generation •OH radical. PAN-CuO-based colorimetric assay used detect...
Hierarchical flower-like NiMnO3 composites were facilely prepared by template-free hydrothermal treatment and calcined under mild conditions. Due to the strong ability absorb oxygen, as-prepared endowed with oxidase-like activity catalyze oxidation of 3,3′,5,5′-tetramethylbenzidine (TMB) a blue product without H2O2. Investigations on mechanism indicate that originates from superoxide radical generation. The was selectively inhibited hydroquinone (HQ), which could reduce oxTMB colorless TMB...
Abstract Chemoenzymatic cascade catalysis has emerged as a revolutionary tool for streamlining traditional retrosynthetic disconnections, creating new possibilities the asymmetric synthesis of valuable chiral compounds. Here we construct one-pot concurrent chemoenzymatic by integrating organobismuth-catalyzed aldol condensation with ene-reductase (ER)-catalyzed enantioselective reduction, enabling formal α-benzylation cyclic ketones. To achieve this, develop pair enantiocomplementary ERs...
Transferrin (Tf), widely known for its role as an iron-binding protein, exemplifies multitasking in biological processes. The of Tf iron metabolism involves both the uptake from by various cells, well endocytosis mediated complex and transferrin receptor (TfR). direct conjugation therapeutic compound immunotoxin studies using peptide or anti-Tf antibodies targeting moieties aims to prolong drug circulation time augment efficient cellular uptake, diminish systemic toxicity, traverse...
Abstract Metal‐enzyme integrated catalysts (MEICs) that combine metal and enzyme offer great potential for sustainable chemoenzymatic cascade catalysis. However, rational design construction of optimal microenvironments accessible active sites in individual nanostructures are necessary but still challenging. Herein, Pd nanoparticles (NPs) Candida antarctica lipase B (CALB) co‐immobilized into the pores surfaces covalent organic frameworks (COFs) with tunable functional groups, affording...
With the aim to provide a highly stable and active biocatalyst, cross-linked enzyme aggregates (CLEAs) of lipase Candida sp. 99-125 were prepared in three-dimensionally ordered macroporous silica materials (CLEAs-LP@3DOM-SiO2). Lipase was first precipitated pores 3DOM SiO2 (named EAs-LP@3DOM-SiO2), further by glutaraldehyde form CLEAs-LP@3DOM-SiO2. Saturated ammonium sulfate used as precipitant with concentration 0.25% (w/w) employed cross-linker. Compared EAs-LP@3DOM-SiO2 native lipase,...
Abstract The direct asymmetric reductive amination of heteroaryl ketones has been a long‐standing synthetic challenge. Here we report the engineering an amine dehydrogenase (AmDH) from Jeotgalicoccus aerolatus for synthesis chiral α‐(hetero)aryl primary amines in excellent conversions (up to 99 %) and enantioselectivities % ee). best AmDH variant ( Ja ‐AmDH‐M3 3 ) exhibited high activity specificity toward alkyl (hetero)aryl ketones, even those bearing bulky chain. An efficient directed...
For synthesizing glycerol carbonate (GC) by a reaction between (GL) and dimethyl (DMC), lipase immobilized on magnetic organosilica nanoflowers was prepared utilized as biocatalyst. Candida antarctica B (CALB) chosen model enzyme for preparing an biocatalyst (CALB@nanoflowers). The obtained CALB@nanoflowers characterized using scanning electron microscopy, transmission confocal laser microscopy. Effects of GL/DMC molar ratio, amount, temperature, surfactant molecular sieve addition, time the...
In this study, nickel-nitrilotriacetic acid-modified viruslike mesoporous silica nanoparticles (Ni-NTA-VMSN) were fabricated by a facile method for the first time. The Ni2+ ions on surface of Ni-NTA-VMSN provided abundant anchoring sites directly selective oriented immobilization His-tagged proteins from crude enzymes. By incubation in organophosphohydrolase (OpdA)-contained cell lysates, nanobiocatalyst, OpdA@Ni-NTA-VMSN, could be constructed. At optimal conditions, specific activity...