A5078972744- Pharmaceutical Practices and Patient Outcomes
- Health Systems, Economic Evaluations, Quality of Life
- Medication Adherence and Compliance
- Pharmaceutical studies and practices
- Lipoproteins and Cardiovascular Health
- Pharmaceutical Economics and Policy
- Antiplatelet Therapy and Cardiovascular Diseases
- Diabetes Treatment and Management
- Hepatitis C virus research
- Pharmacology and Obesity Treatment
- Monoclonal and Polyclonal Antibodies Research
- Trigeminal Neuralgia and Treatments
- Respiratory viral infections research
- Biosimilars and Bioanalytical Methods
- Economic and Financial Impacts of Cancer
- Attention Deficit Hyperactivity Disorder
- Diabetes Management and Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Multiple Myeloma Research and Treatments
- Tuberous Sclerosis Complex Research
- Rheumatoid Arthritis Research and Therapies
- Migraine and Headache Studies
- Autoimmune and Inflammatory Disorders Research
- SARS-CoV-2 detection and testing
- Sympathectomy and Hyperhidrosis Treatments
Optum (United States)
2011-2024
IQVIA (United States)
2021-2024
Florida College
2018-2019
University of Florida
2018-2019
Austin College
2018-2019
Texas College
2018-2019
American Medical Research
2018-2019
University of Nebraska Medical Center
2018-2019
Light Prescriptions Innovators (United States)
2003-2011
Clinical Solutions
2008-2010
OBJECTIVE—The objective of this study was to characterize health care costs associated with diabetic lower-extremity ulcers. RESEARCH DESIGN AND METHODS—Adult patients diabetes who had a ulcer episode during 2000 and 2001 were identified using claims data. Ulcer-related direct computed for each episode. Episodes stratified according severity level based on the Wagner classification. RESULTS—A total 2,253 identified. The mean age 68.9 years, 59% male. average duration 87.3 ± 82.8 days. Total...
Recent pharmacodynamic and retrospective clinical analyses have suggested that proton pump inhibitors (PPIs) may modify the antiplatelet effects of clopidogrel bisulfate.We conducted a cohort study persons enrolled in multistate health insurance plan with commercial Medicare clients to evaluate adverse outcomes patients using plus PPI compared alone. Patients who were discharged from hospital after myocardial infarction (MI) or coronary stent placement treated (n = 1033) matched 1:1 (using...
Diabetes mellitus (DM) affects over 18.2 million Americans and diabetes-related medical costs exceed 132 billion dollars per year, totaling more than 12% of the United States healthcare budget. The Control Complications Clinical Trial demonstrated that intensive insulin therapy control plasma glucose can significantly reduce incidence late diabetic complications delay progression existing conditions in type 1 diabetes. Optimal glycemic often requires to maintain a hemoglobin A(1C) (A1C) less...
A national pharmacy benefits management company implemented a rheumatoid arthritis (RA) disease therapy (DTM) program as an enhanced offering to patients receiving specialty services. The was designed improve medication adherence, maximize therapeutic outcomes, and enhance physical functioning health-related quality of life (HRQOL) by empowering improving their knowledge RA.To evaluate (a) adherence injectable RA medications for participating in DTM compared with nonparticipating at or...
To examine medication adherence among Medicare Part D beneficiaries initiating oral anti-diabetic medications and explore whether there is any association of using mail-order pharmacy (vs. retail pharmacy) with better in this patient population.Using administrative claims data, we conducted a retrospective cohort study on who newly initiated treatment between July 1, 2008 December 31, 2008. Mail-order users were matched to via propensity scoring, controlling for demographic clinical...
To examine the association between atypical antipsychotic medications and incident treatment for diabetes mellitus or hyperlipidemia in elderly adults without diagnoses of schizophrenia bipolar disorder.Two case-control studies using medical pharmacy claims data.United States managed care population from multiple insurance plans.Individuals aged 65 older enrolled a Medicare Advantage commercial (health maintenance organization) health plan western United with no indicating diagnosis disorder...
The 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults emphasizes evidence-based treatment with moderate- high-dose statins for patients at high risk atherosclerotic cardiovascular disease (ASCVD). Whether this new guideline influenced patterns 1 year after its dissemination is unknown.To compare lipid-lowering before and release cholesterol 2 high-risk groups: ASCVD diabetes mellitus.Using pharmacy medical claims from a large...
To determine if switching from select branded to generic equivalent antiepileptic drugs (AEDs) in patients with epilepsy is associated adverse outcomes.A retrospective cohort study using a large health insurance plan claims database comparing who switched brand phenytoin, lamotrigine, or divalproex after 6 months (switch cohorts) matched remained on the (nonswitch cohorts). Primary outcomes measured include incidence rate ratio (IRR) of discontinuation index AED; change dose AED addition...
Attention deficit hyperactivity disorder (ADHD) is a prevalent mental health condition, occurring in 3% to 5% of school-aged children. Although stimulant medications are recommended treatment for this disorder, physicians. views these have not been systematically evaluated.This study examined physician-prescriber perceptions using treat ADHD symptoms children or adolescents.A survey was developed with 4 physicians expert treating The pilot-tested sample 10 practicing A 1,000 physicians,...
While molecular testing is recommended for symptomatic patients suspected of having coronavirus disease 2019 (COVID-19), limited data are available examining real-world use tests severe acute respiratory syndrome (SARS-CoV-2) and the impact SARS-CoV-2 on patient outcomes. In this retrospective cohort study using de-identified administrative claims in Optum Labs Data Warehouse, we identified 2 groups with ≥1 outpatient a procedure code between January 2021 September 2022. Group 1 had CPT...
BACKGROUND: General eligibility criteria used by the Centers for Medicare & Medicaid Services (CMS) to identify patients medication therapy management (MTM) services include having multiple chronic conditions, taking Part D drugs, and being likely incur annual drug costs that exceed a predetermined threshold. The performance of these in identifying greatest need MTM is unknown. Although there are numerous possible versions identification algorithms satisfy criteria, limited data evaluate...
Abstract Purpose Controversy surrounds the question whether thiazolidinediones (TZDs) increase risk of acute myocardial infarction (AMI). This study examined AMI in patients with type 2 diabetes mellitus (T2DM) who were taking TZDs or other antidiabetic medications. Methods Using a nested case‐control design, cohort aged 18–84 years T2DM and use an oral medication exenatide between January 2002 June 2006 was identified. Cases matched up to four controls based on age, gender, health plan,...
The cardiovascular (CV) benefits of lipid-lowering therapy in older adults with hypercholesterolemia and underlying risk factors for coronary artery disease (CAD) have been well documented. Significant reductions the myocardial infarction (MI) death demonstrated statin therapy, that are particular relevance patients diabetes. Managed care interventions prescribers increased use selected drugs such as statins.To (1) measure increase new users statins associated implementation a initiation...
Abstract Objective To assess changes in real‐world use of acute and preventive medications for migraine over a 12‐month follow‐up period the United States following initiation anti‐calcitonin gene‐related peptide (CGRP) pathway monoclonal antibody (mAb) erenumab. Background Early assessments after erenumab have been limited to 6 months follow‐up. Methods This retrospective cohort study used data from IQVIA open‐source longitudinal prescription (LRx) medical (Dx) claims databases. Adult...
Data on the economic burden associated with tuberous sclerosis complex (TSC) among patients epilepsy in United States (US) are limited. This study aimed to assess all-cause and epilepsy-related healthcare resource utilization (HRU) costs US TSC compared but without TSC.This retrospective was conducted using Symphony Health Solutions claims database (April 1, 2017-June 30, 2019). Patients ≥1 medical claim a diagnosis code representing or seizures were assigned cohort if they had for TSC;...
BACKGROUND: Osteoporosis-related fractures are a considerable economic burden on the U.S. health care system. Since 2008, Centers for Medicare & Medicaid Services have adopted Part C Five-Star Quality Rating measure to ensure that woman's previously unaddressed osteoporosis is managed appropriately after fracture. Despite effort improve this gap in care, 2013 CMS plan ratings fact sheet reported an average star rating of 1.4 stars measure, lowest score any across all plans. OBJECTIVE: To...
The utilization of controller medications before initiating a long-acting beta(2)-adrenergic agonist (LABA) and after the Food Drug Administration (FDA) alerts is examined.Electronic claims from health insurer in Western United States were examined during two distinct identification periods: FDA (October 1, 2003, through September 30, 2005) (December 2005, 2006). Identified patients at least 12 years old, newly initiated on an LABA, continuously enrolled preperiod (six months date). Previous...
The AMCP Managed Care & Specialty Pharmacy Annual Meeting 2019 in San Diego, California, is expected to attract more than 4,000 managed care pharmacists and other health professionals who manage evaluate drug therapies, develop networks, work with medical managers information specialists improve the of all individuals enrolled programs. Abstracts program provides a forum through which authors can share their insights outcomes advanced practice. Poster presentations are scheduled for...
AMCP Nexus 2018: Preparing for the Next Generation of Care in Orlando, Florida, is expected to attract more than 2,400 managed care pharmacists and other health professionals who manage evaluate drug therapies, develop networks, work with medical managers information specialists improve all individuals enrolled programs. The Abstracts program provides a forum through which authors can share their insights outcomes advanced practice. Poster author presentations 2018 are scheduled Wednesday,...