Abdelhalem Mesfioui

ORCID: 0009-0007-9931-5377
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Research Areas
  • Tryptophan and brain disorders
  • Stress Responses and Cortisol
  • Circadian rhythm and melatonin
  • Heavy Metal Exposure and Toxicity
  • Biochemical effects in animals
  • Natural Antidiabetic Agents Studies
  • Trace Elements in Health
  • Medicinal Plants and Neuroprotection
  • Essential Oils and Antimicrobial Activity
  • Diet, Metabolism, and Disease
  • Neuroendocrine regulation and behavior
  • Fatty Acid Research and Health
  • Diet and metabolism studies
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Pesticide and Herbicide Environmental Studies
  • Insect Pest Control Strategies
  • Schizophrenia research and treatment
  • Birth, Development, and Health
  • Genetics and Physical Performance
  • Phytochemistry and Biological Activities
  • Sleep and Wakefulness Research
  • Aluminum toxicity and tolerance in plants and animals
  • Neuroscience and Neuropharmacology Research
  • Ziziphus Jujuba Studies and Applications
  • Alzheimer's disease research and treatments

Université Ibn-Tofail
2016-2025

Sidi Mohamed Ben Abdellah University
2023

Laboratoire de Mathématiques d'Orsay
1998

In recent years, the low Zn content of wheat has become critical. Consequently, solutions that can improve nutrition are highly researched. present investigation, we aimed to evaluate potential benefits phosphate-solubilizing bacteria isolated from Ziziphus lotus on seedling growth. Based criteria, four strains, J16, J143, J146, and J158, were identified by 16SrRNA gene sequencing as Pseudomonas moraviensis, Bacillus halotolerans, Enterobacter hormaechei, frederiksbergensis, respectively....

10.3390/agriculture11040316 article EN cc-by Agriculture 2021-04-04

The essential oils yield of Cedrus atlantica, Chenopodium ambrosioides and Eucalyptus camaldulensis was different. C. gave a relatively higher (2.1 ± 0.1%), while that atlantica low (1.0 0.1%) E. lower (0.75 0.1% dry matter). active ingredients the some their biological effects were also determined. characterization chemical compositions showed three essences have different profiles: richer in sesquiterpenes (β-Himachalene (54.21%) γ -Himachalene (15.54%)), very rich monoterpene peroxides...

10.3390/molecules28072974 article EN cc-by Molecules 2023-03-27

E arly life stress (ELS) such as parental loss, low socioeconomic status, childhood maltreatment, and malnutrition or viral infection

10.17582/journal.aavs/2024/12.3.457.466 article EN Advances in Animal and Veterinary Sciences 2024-01-01

Nickel (Ni) toxicity has been reported to produce biochemical and behavioral dysfunction. The present study was undertaken examine whether Ni chronic administration can induce alterations of affective cognitive behavior oxidative stress in male female rats. Twenty-four rats, for each gender, divided into control three test groups (n = 6), were injected intraperitoneally with saline (0.9% NaCl) or NiCl2 (0.25 mg/kg, 0.5 mg/kg 1 mg/kg) 8 weeks. After treatment period, animals tested the...

10.3390/brainsci8080141 article EN cc-by Brain Sciences 2018-07-31

Aluminum (Al) is a well-established neurotoxicant, affecting various regions of the brain and causing many neuropathological neurobehavioral abnormalities as well oxidative stress (OS).Conversely, melatonin (MEL) has been considered an antidepressant, anxiolytic substance protects neurons from OS.The present study was designed to evaluate neuroprotection effect MEL against Al neurotoxicity OS in male Wistar rats.Rats received intraperitoneal and/or single intrahippocampal injection NaCl, or...

10.17582/journal.aavs/2023/11.5.711.719 article EN Advances in Animal and Veterinary Sciences 2023-01-01

Fructose high diet constitutes a risk factor for metabolic disorders (Tovoli et al., 2023), in addition, it negatively affects the structure and functioning of nervous system mainly brain.Neuropsychiatric symptoms are common obesity significantly influence social quality life people with Research

10.17582/journal.aavs/2024/12.4.614.623 article EN Advances in Animal and Veterinary Sciences 2024-01-01

Previous studies have shown that variations in the CD36 gene may affect phenotypes associated with fat metabolism as protein facilitates transport of fatty acids to mitochondria for oxidation. However, no previous study has tested whether are sports performance. We investigated genotypic and allelic distribution single-nucleotide polymorphism (SNP) rs1761667 elite Moroccan athletes (cyclists hockey players) comparison healthy non-athletes same ethnic origin. Forty-three male (nineteen...

10.3390/genes15040419 article EN Genes 2024-03-27

Background and Objectives: The insertion/deletion (I/D) polymorphism in ACE, the gene encoding angiotensin-converting enzyme (ACE), has been suggested as a genetic variation that can influence exercise performance risk of injury elite athletes. I allele associated with enhanced endurance reduced inflammation, while D improved strength power activities. However, role this variant incidence non-contact is underexplored. This study investigated possible association ACE I/D genotypes Moroccan...

10.3390/medicina61010098 article EN cc-by Medicina 2025-01-10

Purpose: Metabolic syndrome is a cluster of risk factors for diabetes and cardiovascular diseases that includes central obesity, hypertension, glucose intolerance, high triglyceride, low high-density lipoprotein cholesterol. Its prevalence rapidly increasing worldwide. This study aimed to estimate the metabolic associated in representative sample Morocco adults using 2009 joint interim statement definition. Patients methods: We analyzed data 820 patients aged 19 years older. For diagnosis,...

10.2147/dmso.s61245 article EN cc-by-nc Diabetes Metabolic Syndrome and Obesity 2014-07-01

Introduction . This study sought to investigate potential determinants of patient delay among Moroccan women with cervical cancer. Methods A cross-sectional was conducted from June 2014 2015 at the National Institute Oncology in Rabat. Data were collected using questionnaire patients cancer locally advanced or metastatic (stages IIA–IVB). Medical records abstracted complete clinical information. An interval longer than 90 days between discovery initial symptoms and presentation a provider...

10.1155/2016/4840762 article EN cc-by Obstetrics and Gynecology International 2016-01-01

Copper (Cu) is a heavy metal with the ability to induce, at high levels, neurobehavioral alterations, and oxidative stress (OS). On other hand, melatonin (Mel) neurohormone that protects neurons from OS has modulatory effect on several behavioral processes. The present experiment was aimed examine of Mel treatment Cu-induced anxiety-like, depression-like behaviors, memory impairment, in hippocampus. Herein, adult Wistar rats both genders received daily (4 mg/kg) thirty minutes before CuCl2...

10.1080/01480545.2020.1858853 article EN Drug and Chemical Toxicology 2021-01-07

The carmine cochineal Dactylopius opuntiae (Cockerell) is the major insect pest of prickly-pear cactus Opuntia ficus-indica (L.) in Morocco. present study investigated insecticidal activities six essential oils (EOs) against nymphs and adult females D. applied singly or combination with a detergent under laboratory field conditions. Under conditions, M. pulegium O. vulgare L. showed high level activity at 5%, 98% 92% females' mortality, respectively, 5 days after treatments. vulgaris 5%...

10.3390/insects12111007 article EN cc-by Insects 2021-11-09

Abstract Background Difficulties in interacting and adapting to the social world are central complaint faced by patients with schizophrenia. These people often socially isolated, unemployed may find it difficult live independently. Aim This study aims evaluate functioning of schizophrenic patients, highlight various factors associated alteration patients. Methods We conducted a prospective descriptive analytical population 72 between 19 59 years old, clinically stabilized, diagnosed followed...

10.1186/s41983-023-00714-7 article EN cc-by The Egyptian Journal of Neurology Psychiatry and Neurosurgery 2023-09-05

The main objective of this work is to study the effect chronic administration cadmium (Cd) on level depression-like, anxiety-like, memory state and oxidative stress in male female Wistar rats. For purpose, was conducted with 24 rats for each gender. Four groups were constituted: (Group 1: Control): received saline solution NaCl (0.9%), 2: Cd-0.25; Group 3: Cd-0.5; 4: Cd-1): daily 0.25 mg/kg, 0.5 mg/kg 1 Cd respectively during 8 weeks. After treatment period, animals tested open-field,...

10.4236/jbbs.2018.85016 article EN Journal of Behavioral and Brain Science 2018-01-01
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