- Advanced biosensing and bioanalysis techniques
- MicroRNA in disease regulation
- Bacteriophages and microbial interactions
- RNA Interference and Gene Delivery
- Biosensors and Analytical Detection
Yixing People's Hospital
2024
Jiangsu University
2024
Xiamen University
2011
We have developed a novel method for efficiently screening affinity ligands (aptamers) from complex single-stranded DNA (ssDNA) library by employing single-molecule emulsion polymerase chain reaction (PCR) based on the agarose droplet microfluidic technology. In typical systematic evolution of exponential enrichment (SELEX) process, enriched is sequenced first, and tens to hundreds aptamer candidates are analyzed via bioinformatic approach. Possible then chemically synthesized, their binding...