Loes J.A. Reichman
- Intracranial Aneurysms: Treatment and Complications
- Neurosurgical Procedures and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Viral Infections and Vectors
- Mosquito-borne diseases and control
- Chemical and Physical Studies
- Sleep and related disorders
- Neuroscience of respiration and sleep
- Obstructive Sleep Apnea Research
- Spaceflight effects on biology
- Circadian rhythm and melatonin
- Vector-borne infectious diseases
Ziekenhuis Groep Twente
2020-2024
University Medical Center Utrecht
2022
Utrecht University
2022
Amsterdam Neuroscience
2022
The results of the ULTRA trial showed that ultra-early and short-term treatment with tranexamic acid (TXA) does not improve clinical outcome after aneurysmal subarachnoid hemorrhage (aSAH). Possibly, lack a beneficial effect in all patients aSAH is masked by antagonistic effects TXA certain subgroups. In this post hoc subgroup analysis, we investigated on good-grade poor-grade aSAH.
Abstract Purpose Melatonin aids in the synchronization of circadian rhythm to external environment. Few studies have tried elucidate relationship between melatonin and obstructive sleep apnea syndrome (OSAS). These often include few patients, do not differentiate OSAS severity and/or analyse a 24-h profile. This study set out investigate disease dependent differences salivary secretion patients compared reference population retrospective design. Methods profiles 169 were analysed (55 light,...
The ULTRA trial showed that ultra-early and short-term tranexamic acid treatment after subarachnoid hemorrhage did not improve clinical outcome at 6 months. An expected proportion of the included patients experienced nonaneurysmal hemorrhage. In this post hoc study, we will investigate whether in with aneurysmal improves months.The is a multicenter, prospective, randomized, controlled, open-label blinded assessment, conducted between July 24, 2013, January 20, 2020. After confirmation on...