A5018411671- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Aortic Disease and Treatment Approaches
- Anesthesia and Pain Management
- Nutrition and Health in Aging
- Sports injuries and prevention
- Pregnancy-related medical research
- Pancreatitis Pathology and Treatment
- Liver Disease Diagnosis and Treatment
- Winter Sports Injuries and Performance
- Spinal Hematomas and Complications
- Spinal Fractures and Fixation Techniques
- Acute Ischemic Stroke Management
- Enhanced Recovery After Surgery
- Intracerebral and Subarachnoid Hemorrhage Research
- Pancreatic and Hepatic Oncology Research
- Lower Extremity Biomechanics and Pathologies
- Clinical Nutrition and Gastroenterology
Isala
2019-2024
Yogyakarta State University
2024
University Medical Center Utrecht
2022
Utrecht University
2022
Amsterdam Neuroscience
2022
Abstract Background Previous randomised controlled trials could not demonstrate that surgical evacuation of intracerebral haemorrhage (ICH) improves functional outcome. Increasing evidence suggests minimally invasive surgery may be beneficial, in particular when performed early after symptom onset. The aim this study was to investigate safety and technical efficacy endoscopy-guided patients with spontaneous supratentorial ICH. Methods Dutch Intracerebral Haemorrhage Surgery Trial pilot a...
The results of the ULTRA trial showed that ultra-early and short-term treatment with tranexamic acid (TXA) does not improve clinical outcome after aneurysmal subarachnoid hemorrhage (aSAH). Possibly, lack a beneficial effect in all patients aSAH is masked by antagonistic effects TXA certain subgroups. In this post hoc subgroup analysis, we investigated on good-grade poor-grade aSAH.
Abstract Background and objectives The modified Rankin Scale (mRS) is one of the most frequently used outcome measures in trials patients with an aneurysmal subarachnoid hemorrhage (aSAH). assessment method mRS often not clearly described trials, while might influence score. aim this study to evaluate inter-method reliability different methods mRS. Methods This a prospective, randomized, multicenter follow-up at 6 weeks months. Patients aged ≥ 18 years aSAH were randomized either structured...
Patients with large annular defects following lumbar microdiscectomy for disc herniation are at increased risk symptomatic recurrence and reoperation.To determine whether a bone-anchored closure device in addition to resulted lower reherniation reoperation rates vs alone.This secondary analysis of multicenter randomized clinical trial reports 5-year follow-up enrolled patients between December 2010 October 2014 21 sites. this study had defect (6-10 mm width) treatment herniation. Statistical...
The ULTRA trial showed that ultra-early and short-term tranexamic acid treatment after subarachnoid hemorrhage did not improve clinical outcome at 6 months. An expected proportion of the included patients experienced nonaneurysmal hemorrhage. In this post hoc study, we will investigate whether in with aneurysmal improves months.The is a multicenter, prospective, randomized, controlled, open-label blinded assessment, conducted between July 24, 2013, January 20, 2020. After confirmation on...
A prospective, Phase IV, multicenter, randomized study.The aim of this study was to compare vertebral fusion success rates following posterolateral [(PLF)/posterolateral intertransverse (PITF)] surgery. The surgical procedure combined posterior lumbar interbody (PLIF) and PLF with internal fixation over one or two levels using silicated calcium phosphate (SiCaP) bone morphogenetic protein (BMP)-2 as graft material in patients a degenerative disorder the spine.Few controlled trials have...
Objective: To determine whether implanting an annular closure device (ACD) following a lumbar discectomy procedure in patients with large defects the annulus fibrosus lowers risk of reoperation after 4 years. Methods: In multicenter randomized trial, single-level were intraoperatively to additionally receive ACD or no treatment (Controls). Clinical and imaging follow-up performed at routine intervals over years follow-up. Main outcomes included reoperations treated level, leg pain scores on...
Abstract Purpose The modified Rankin Scale (mRS), a clinician-reported outcome measure of global disability, has never been validated in patients with aneurysmal subarachnoid hemorrhage (aSAH). aims this study are to assess: (1) convergent validity the mRS; (2) responsiveness and (3) distribution mRS scores across patient-reported measures (PROMs). Methods This is prospective randomized multicenter study. was scored by physician for all patients, subsequently structured interview half...
Training at high intensity without proper warm-up and cool-down can cause shin splint injuries in runners. This may lead to a decline the athlete’s performance during training competition. study aims determine effect of PNF therapy on marathon research employs quasi-experimental approach with One Group Pretest-Posttest Design. Data collection methods include tests measurements using goniometer assess joint range motion (ROM) Visual Analogue Scale (VAS) measure pain levels. The population...
Abstract Purpose The modified Rankin Scale (mRS), a clinician-reported outcome measure of global disability, has never been validated in patients with aneurysmal subarachnoid hemorrhage (aSAH). aims this study are to assess: 1) convergent validity the mRS; 2) responsiveness and 3) distribution mRS scores across patient reported measures (PROMs). Methods This is prospective, randomized, multicenter study. was scored by physician for all patients; subsequently one half structured interview...