- Inflammatory mediators and NSAID effects
- DNA Repair Mechanisms
- Dental materials and restorations
- Microtubule and mitosis dynamics
- Thin-Film Transistor Technologies
- ZnO doping and properties
- Microfluidic and Capillary Electrophoresis Applications
- Cancer-related molecular mechanisms research
- Photodynamic Therapy Research Studies
- Cytokine Signaling Pathways and Interactions
- Mycotoxins in Agriculture and Food
- Nuclear Structure and Function
- Cancer, Hypoxia, and Metabolism
- Cancer Treatment and Pharmacology
- Endodontics and Root Canal Treatments
- NF-κB Signaling Pathways
- Perovskite Materials and Applications
- Organic Light-Emitting Diodes Research
- Semiconductor materials and devices
- Soft Robotics and Applications
- Endoplasmic Reticulum Stress and Disease
- Genital Health and Disease
- Conducting polymers and applications
- Hydraulic and Pneumatic Systems
- Vitamin K Research Studies
National Tsing Hua University
2022-2025
Queen's University
2020
Taipei City University of Science and Technology
2013
National Taiwan University Hospital
2009
Xi'an Peihua University
1949
Abstract Centrosomes are tubulin-based organelles that undergo glutamylation, a post-translational modification conjugates glutamic acid residues to tubulins. Although centrosomal glutamylation has been known for several decades, how this regulates centrosome structure and function remains unclear. To address long-standing issue, we developed method spatiotemporally reduce by recruiting an engineered deglutamylase centrosomes. We found largely unaffected hypoglutamylation. Intriguingly,...
Abstract Epidemiological studies have shown a strong association between environmental exposure to betel quid (BQ) and oral cancer. Areca nut (AN), an ingredient of BQ, contains genotoxic mutagenic compounds. In this study, we found that AN extract (ANE) inhibited the growth Chinese hamster ovary cells (CHO‐K1) in dose‐ time‐dependent manner. Intracellular reactive oxygen species (ROS) levels micronuclei (MN) frequency were significantly increased following ANE treatment CHO‐K1 cells....
Background: Tongue cancer metastasis is mainly through blood stream and possibly associated with tumor cell‐induced platelet aggregation (TCIPA). Methods: Platelet was induced by different amounts of SAS tongue cells with/without inhibitors the latent period for induction recorded. Gene expression analyzed reverse transcriptase‐polymerase chain reaction. Results: (4 × 10 4 to 1 6 cells/ml) in a cell density‐dependent manner. The reduced from 11.3 min (2 5 0.9 (5 cells/ml). extent increased...
Human Cep57 is a coiled-coil scaffold at the pericentriolar matrix (PCM), controlling centriole duplication and centrosome maturation for faithful cell division. Genetic truncation mutations of are associated with mosaic-variegated aneuploidy (MVA) syndrome. During interphase, forms complex Cep63 Cep152, serving as regulators maturation. However, molecular interplay these essential scaffolding proteins remains unclear. Here, we demonstrate that undergoes liquid–liquid phase separation (LLPS)...
In this letter, the homo-multilayer indium tin oxide (ITO) film is deposited by continuous roll-to-roll sputtering at room temperature. While piling up to homo-5-layer ITO film, best transmittance of 87.66% in visible wavelength and sheet resistance 68Ω/□ are obtained. The TEM diffraction images films show crystalline optimal 5-layer structure, nano-sized grains (~50 nm) distributed uniformly all over surface from SEM investigation.
This work demonstrates that PLECs made with a low AgOTf salt concentration exhibit record luminance, efficiency, lifetime and response speed.
In a study of 288 samples blood from 152 cases, gradual appearance Ach toward the 2nd trimester pregnancy, an increase with onset labor, and disappearance 48 hours or more after labor were demonstrated. Blood 20 normal subjects both sexes showed no evidence same test.