A5051834623- Bacteriophages and microbial interactions
- Genomics and Phylogenetic Studies
- Microbial Community Ecology and Physiology
- Plant Virus Research Studies
- Advanced biosensing and bioanalysis techniques
- Protist diversity and phylogeny
Max Planck Institute for Marine Microbiology
2021-2023
Carl von Ossietzky Universität Oldenburg
2020
Ecological differentiation between strains of bacterial species is shaped by genomic and metabolic variability. However, connecting genotypes to ecological niches remains a major challenge. Here, we linked geno- phenotypes contextualizing pangenomic, exometabolomic physiological evidence in twelve the marine bacterium Alteromonas macleodii, illuminating adaptive strategies carbon metabolism, microbial interactions, cellular communication iron acquisition. In A. macleodii strain MIT1002,...
Environmental virus metagenomes, commonly referred to as "viromes", are typically generated by physically separating virus-like particles (VLPs) from the microbial fraction based on their size and mass. However, most methods used purify VLPs, enrich extracellular vesicles (EVs) gene transfer agents (GTAs) simultaneously. Consequently, sequence space traditionally a "virome" contains host-associated sequences, transported via EVs or GTAs. We therefore propose call genetic material isolated...
Abstract Motivation Viruses infect, reprogram and kill microbes, leading to profound ecosystem consequences, from elemental cycling in oceans soils microbiome-modulated diseases plants animals. Although metagenomic datasets are increasingly available, identifying viruses them is challenging due poor representation annotation of viral sequences databases. Results Here, we establish efam, an expanded collection Hidden Markov Model (HMM) profiles that represent protein families conservatively...
Archaeal pleomorphic viruses belonging to the Pleolipoviridae family represent an enigmatic group as they exhibit unique genomic features and are thought have evolved through recombination with different archaeal plasmids. However, most of our understanding diversity evolutionary trajectories this clade comes from a handful isolated representatives. Here we present 164 new genomes pleolipoviruses obtained metagenomic data Australian hypersaline lakes publicly available data. We perform...
The 2023 International Virus Bioinformatics Meeting was held in Valencia, Spain, from 24–26 May 2023, attracting approximately 180 participants worldwide. primary objective of the conference to establish a dynamic scientific environment conducive discussion, collaboration, and generation novel research ideas. As first in-person event following SARS-CoV-2 pandemic, meeting facilitated highly interactive exchanges among attendees. It served as pivotal gathering for gaining insights into...
Even though viruses and plasmids are both drivers of horizontal gene transfer, they differ fundamentally in their mode transfer. Virus genomes enclosed virus capsids not dependent on cell-to-cell contacts for dissemination. In contrast, the transfer most often requires physical contact between cells. However, plasmid pR1SE
Abstract Marine environmental virus metagenomes, commonly referred to as ’viromes’, are typically generated by physically separating virus-like particles (VLPs) from the microbial fraction based on their size and mass. However, most methods used purify VLPs, enrich extracellular vesicles (EVs) gene transfer agents (GTAs) simultaneously. Consequently, sequence space traditionally a ’virome’ contains host-associated sequences, transported via EVs or GTAs. We therefore propose call genetic...