A5064348132- Glaucoma and retinal disorders
- Corneal surgery and disorders
- Ocular Surface and Contact Lens
- Retinal Diseases and Treatments
- Water Quality Monitoring Technologies
- Intraocular Surgery and Lenses
Glaukos (United States)
2023-2025
University of Da Nang
2021
This prospective, multicenter, randomized, double-masked pivotal phase 3 trial evaluated the efficacy and safety of travoprost intracameral SE-implant (slow-eluting implant, intended commercial product) FE-implant (fast-eluting included primarily for masking purposes) compared to twice-daily (BID) timolol ophthalmic solution, 0.5% in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT). The enrolled adult OAG OHT an unmedicated mean diurnal intraocular pressure (IOP) ≥ 21 IOP...
A randomized, double-masked, multicenter, phase 2 trial to evaluate the long-term safety and efficacy of travoprost intraocular implant, an extended-release drug delivery system designed provide uninterrupted sustained pressure (IOP)-lowering therapy, thereby reducing patient treatment burden improving adherence with IOP-lowering medication. Patients open-angle glaucoma or ocular hypertension were administered a fast-eluting implant (FE n = 51) received twice-daily (BID) placebo eye drops,...
To determine the aqueous humor (AH) exposure to travoprost free acid (TFA) and in vivo elution rate of over a 24-month period subjects with open-angle glaucoma administered intracameral implant, 75 µg. In this prospective, single-center, open-label study, 210 (7 cohorts 30 each) were implant followed for 3-24 months. At pre-determined timepoints (3, 6, 12, 15, 18, 21, 24 months), AH was collected, new administered, prior removed. samples assayed TFA concentrations using validated liquid...
This study was conducted to analyze and compare the intraocular pressure (IOP) treatment effect of slow-eluting (SE) travoprost intracameral implant IOP topical prostaglandin analog (PGA) monotherapy in a subgroup subjects who were on pre-study PGA prior enrollment two pivotal phase 3 trials implant. A combined population 133 from trials, at screening, subsequently underwent washout period their PGA, then randomized administered an SE The analyzed for effects in-study Paired t-tests used...
The Vu Gia - Thu Bon river system in Central Vietnam is one of the most complex systems many respects. Problems natural disasters and man-made occur every year on this because it plays an important role provinces Kon Tum, Quang Nam, Da Nang city. In dry season, provides fresh water for a large population area, especially But recent times, situation salty ginseng area quite serious. So, work, we research develop Decision Support System (DSS) saline control entire basin Vietnam. This was able...