Frédérique Dufour‐Gaume

ORCID: 0009-0008-0632-0247
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About
Contact & Profiles
Research Areas
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Blood donation and transfusion practices
  • Trauma and Emergency Care Studies
  • Immune Response and Inflammation
  • Disaster Response and Management
  • Blood transfusion and management
  • Chemokine receptors and signaling
  • Viral Infections and Vectors
  • Intracranial Aneurysms: Treatment and Complications
  • Mechanical Circulatory Support Devices
  • Neutrophil, Myeloperoxidase and Oxidative Mechanisms
  • Long-Term Effects of COVID-19
  • Immune cells in cancer
  • Viral Infections and Outbreaks Research
  • Virology and Viral Diseases
  • Hemoglobin structure and function
  • Gestational Trophoblastic Disease Studies
  • Cardiac Arrest and Resuscitation
  • Cerebrovascular and genetic disorders
  • COVID-19 Clinical Research Studies
  • Parvovirus B19 Infection Studies
  • Cerebrovascular and Carotid Artery Diseases
  • Retinal and Optic Conditions
  • Heme Oxygenase-1 and Carbon Monoxide
  • Animal testing and alternatives

Service de Santé des Armées
2023-2025

Université Nantes Angers Le Mans
2016

Hôpital d'instruction des Armées Desgenettes
2009

Abstract Background Hemorrhagic shock is well documented as a leading cause of preventable fatalities among military casualties. During operations plasma can be transfused while waiting for whole blood. This study was conducted to assess the safety and efficacy two new freeze‐dried formulations in porcine model traumatic hemorrhagic shock. Study Design Methods In face species‐specific transfusion, transfusible blood products were derived from sources. The three lyophilized (LP) evaluated:...

10.1111/trf.17971 article EN Transfusion 2024-08-09

Cytokines secreted by individual immune cells regulate tissue regeneration and allow communication between various cell types. bind to cognate receptors trigger the healing process. Determining orchestration of cytokine interactions with their on cellular targets is essential fully understand process inflammation regeneration. To this end, we have investigated Interleukin-4 (IL-4)/Interleukin-4 receptor (IL-4R) Interleukin-10 (IL-10)/Interleukin-10 (IL-10R) using in situ Proximity Ligation...

10.20944/preprints202304.0741.v1 preprint EN 2023-04-23

Cytokines secreted by individual immune cells regulate tissue regeneration and allow communication between various cell types. bind to cognate receptors trigger the healing process. Determining orchestration of cytokine interactions with their on cellular targets is essential fully understanding process inflammation regeneration. To this end, we have investigated Interleukin-4 (IL-4)/Interleukin-4 receptor (IL-4R) Interleukin-10 (IL-10)/Interleukin-10 (IL-10R) using in situ Proximity...

10.3390/cells12111522 article EN cc-by Cells 2023-05-31

High-intensity conflicts are on Europe's doorstep. The French expertise in the medical management of frontline casualties overseas operations is well established. However, severe trauma, we lack data injuries identified by body scanners field. Understanding associations between injury mechanisms and radiological lesions would enable us to anticipate surgical management. To study this possible link, collected interpreted scanogaphic analyzed them according lesion mechanisms, following...

10.1093/milmed/usae458 article EN Military Medicine 2024-10-10

Background: In France, in 2015, prehospital emergency doctors were faced with civilian casualties hemorrhagic shock resulting from terrorist attacks automatic rifle fire and explosive weapons. The present study aimed to evaluate the impact of these on advanced life support (ALS) team’s practices equipment physician training management traumatic shock.Methods: This before-and-after multicenter evaluated professional based a questionnaire sent department heads medical practitioners 370 ALS...

10.5055/ajdm.2021.0408 article EN American Journal of Disaster Medicine 2021-12-01
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