- Education and Learning Interventions
- Diverse Approaches in Healthcare and Education Studies
- Education, Safety, and Science Studies
- Healthcare Education and Workforce Issues
- Educational Research and Pedagogy
- Educational Systems and Policies
- Immune Cell Function and Interaction
- Cytomegalovirus and herpesvirus research
- Innovations in Medical Education
- Technology Adoption and User Behaviour
- Sarcoma Diagnosis and Treatment
- Cancer-related Molecular Pathways
- Psychosocial Factors Impacting Youth
- Diverse Topics in Contemporary Research
- Digital Marketing and Social Media
- CAR-T cell therapy research
- Fatigue and fracture mechanics
- Job Satisfaction and Organizational Behavior
- Simulation-Based Education in Healthcare
- Gastric Cancer Management and Outcomes
- Chronic Lymphocytic Leukemia Research
- RNA modifications and cancer
- Clinical Reasoning and Diagnostic Skills
- Education, Achievement, and Giftedness
- RNA Interference and Gene Delivery
Gumi Electronics & Information Technology Research Institute (South Korea)
2023-2024
Northwell Health
2010-2024
Pusan National University Hospital
2019-2024
Feinstein Institute for Medical Research
2010-2024
Pusan National University
2024
Myongji University
2022
Sungkyunkwan University
2013-2020
Stony Brook University Hospital
2018-2020
Samsung (South Korea)
2017-2020
Children's Cancer Institute Australia
2017-2019
This study examines smartphone adoption behavior among A merican college students by combining all components of innovation diffusion theory ( IDT ), the technology acceptance model TAM value‐based VAM and social influence SI ) model. Data indicate that rates are beyond early majority now approaching late majority. The findings analysis variance tests revealed variables , varied across adopter groups: current adopter's mean values were highest, followed those potential nonadoption groups....
Teamwork, a skill critical for quality patient care, is recognized as core competency by the Accreditation Council Graduate Medical Education (ACGME). To date, there no consensus on how to effectively teach these skills in forum that engages learners, immerses members life-like activities, and builds both trust rapport. Recreational 'Escape Rooms' have gained popularity creating environment rewards players working together, solving puzzles, completing successions of mind-bending tasks order...
Medical errors are the eighth leading cause of mortality in United States and contribute to over one million preventable injuries. In an effort prevent medical errors, reporting systems serve as invaluable tools detect patient safety events quality problems longitudinally. Historically, trainees (i.e., students residents) rarely submit incident reports for encountered threats. The authors propose immersive learning experience utilizing gamification theory leveraging increasingly popular...
Abstract Clinical progression of B cell chronic lymphocytic leukemia (B-CLL) reflects the clone’s Ag receptor (BCR) and involves stroma-dependent B-CLL growth within lymphoid tissue. Uniformly elevated expression TLR-9, occasional MYD88 mutations, BCR specificity for DNA or Ags physically linked to together suggest that TLR-9 signaling is important in driving patients. Nevertheless, reports apoptosis after exposure CpG oligodeoxynucleotide (ODN) raised questions about a central role TLR-9....
This study analyzed the experiences of children MZ generation using infant education institutions or daycare centers, and qualitatively preferences for institutional operation in-depth interviews. Seven mothers one father participated in interviews, centering on eight parents who applied to S center D metropolitan city. As a result deriving subject words concepts through continuous comparative analysis, total 97 pages interview transcripts were classified into expectations demands...
// Sun Och Yoon 1, * , Eun Kyung Kim Mira Lee 1 Woon Yong Jung 2 Hyunjoo 3 Youngran Kang You-Jin Jang 4 Soon Won Hong Seung Ho Choi 5 and Woo Ick Yang Department of Pathology, Yonsei University College Medicine, Seoul, Korea Guro Hospital, Kangbuk Samsung Sungkyunkwan Surgery, These authors have contributed equally to this work Correspondence to: Yoon, e-mail: soyoon@yuhs.ac ; revita@naver.com Keywords: microenvironment, residual disease, hsa-microRNA-146b-5p, NOVA1, stromal cells Received:...
Previous studies have demonstrated aberrant Brahma-related gene 1 (BRG1) expression in various tumor types. Increased BRG1 has recently been shown to correlate with aggressive oncogenic behavior many different types of human cancer. However, the role breast cancer development and progression is not fully understood.We evaluated 224 patients invasive ductal carcinoma (IDC) using tissue microarray samples immunohistochemistry. We also investigated whether status associated clinicopathological...
Patient derived xenografts (PDXs) have become a vital, frequently used, component of anti-cancer drug development. PDXs can be serially passaged in vivo for years, and shared across laboratories. As consequence, the potential mis-identification cross-contamination is possible, yet authentication appears limited. We present PDX Authentication System (PAS), by combining commercially available OpenArray assay single nucleotide polymorphisms (SNPs) with in-house R studio programs, to validate...
Aims CD 44 has been reported as a negative prognostic marker in gastric cancer. It interacts with moesin epithelial–mesenchymal transition. To date, to our knowledge, there no clinical study dealing the relationship between and adenocarcinoma. We analysed expression of adenocarcinoma tissue, correlations clinicopathological factors. Methods results A retrospective analysis was made 430 patients who had undergone gastrectomy at Korea University Guro Hospital 2002 2005 for Using tissue...
Liposarcoma (LPS) is a tumor derived from adipose tissue, and has the highest incidence among soft tissue sarcomas. Dedifferentiated liposarcoma (DDLPS) malignant with poor prognosis. Recurrence metastasis rates in LPS remain high even after chemotherapy radiotherapy following complete resection. Therefore, development of advanced treatment strategies for required. In present study, we investigated effect necrosis factor-related apoptosis-inducing ligand (TRAIL) treatment, combination using...
Abstract Within inflammatory environments, B cells encountering foreign or self-Ag can develop tertiary lymphoid tissue expressing activation-induced cytosine deaminase (AID). Recently, this DNA-modifying enzyme was detected in nonlymphoid within several inflamed tissues and strongly implicated malignant transformation. This study examines whether a cyclooxygenase 2 (COX-2) pathway, often linked to inflammation, influences AID expression activated lymphocytes. In paper, we report that...
CLL B cells express elevated pro-survival BCL2, and its selective inhibitor, venetoclax, significantly reduces leukemic cell load, leading to clinical remission. Nonetheless, relapses occur. This study evaluates the hypothesis that progressively diminished BCL2 protein in cycling within patient lymph node niches contributes relapse. Using CFSE-labeled, purified populations known respond with vigorous d6 cultures stimulated TLR9-activating ODN (oligodeoxynucleotide) + IL15, we show declines...
Resting mature human B cells undergo a dynamic process of clonal expansion, followed by contraction, during an in vitro response to surrogate C3d-coated Ag and innate immune system cytokines, IL-4 BAFF. In this study, we explore the mechanism for contraction through following time- division-influenced expression several pro- anti-apoptotic proteins within CFSE-labeled cultures. Several findings, involving both mouse cells, show that mitochondria-dependent apoptotic pathway p53 contributes...
A comprehensive fatigue program was undertaken at room temperature and −45°C (−50°F) for five representative carbon or low alloy cast steels. Constant amplitude high cycle axial behavior, cyclic stress-strain constant-amplitude fatigue-crack-growth behavior variable-amplitude fatigue-crack-initiation -growth were determined. The resistance usually equal to better than except one material under variable crack growth conditions. SEM analysis revealed similar mechanisms both temperature, even...