A5101836634- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Immune Cell Function and Interaction
- Liver Disease Diagnosis and Treatment
- Organ Donation and Transplantation
- Hepatocellular Carcinoma Treatment and Prognosis
- T-cell and B-cell Immunology
- Sarcoma Diagnosis and Treatment
- Immunotherapy and Immune Responses
- Neurological Complications and Syndromes
- Hepatitis B Virus Studies
- Liver physiology and pathology
- Hepatitis C virus research
- Pancreatic function and diabetes
- CAR-T cell therapy research
- Renal and Vascular Pathologies
- Liver Disease and Transplantation
- Pneumocystis jirovecii pneumonia detection and treatment
- Hematopoietic Stem Cell Transplantation
- Pluripotent Stem Cells Research
- Cardiac tumors and thrombi
- Cancer, Hypoxia, and Metabolism
- Polyomavirus and related diseases
- Cancer Immunotherapy and Biomarkers
- Diabetes and associated disorders
Sungkyunkwan University
2012-2021
Samsung Medical Center
2012-2021
Samsung (South Korea)
2008-2019
Kim's Eye Hospital
2008-2018
Konyang University
2018
Three-dimensional (3D) bioprinting technology is a promising new in the field of bioartificial organ generation with regard to overcoming limitations supply. The cell source for very important. Here, we generated 3D hepatic scaffold mouse-induced hepatocyte-like cells (miHeps), and investigated whether their function was improved after transplantation vivo. To generate miHeps, mouse embryonic fibroblasts (MEFs) were transformed pMX retroviruses individually expressing transcription factors...
Glycogen storage disease type I (GSD-I) is a group of autosomal recessive disorders with an incidence 1 in 100,000. The two major subtypes are GSD-Ia, caused by deficiency glucose-6-phosphatase (G6Pase), and GSD-Ib, glucose-6-phosphate transporter (G6PT). We report that substantial improvement was achieved following several infusions hepatocytes patient GSD-Ib. Hepatocytes were isolated from the unused cadaveric whole livers donors. At first transplantation, approximately 2 × 109 cells (2%...
Abstract Background Hepatectomy is the standard treatment for HCC. However, large HCC poses a difficult challenge because of technical complexity surgical resection and fear postoperative hepatic decompensation. We analyzed outcome prognostic factors in patients with hepatocellular carcinoma (HCC ≥10 cm) after surgery. Methods retrospectively investigated medical records 91 who had undergone hepatectomy between January 2006 June 2010. A survival analysis was performed utilizing Kaplan-Meier...
The disparity between patients awaiting transplantation and available organs has widened, resultant organ shortage became a world crisis. community made considerable progress in national donation system Korea, significant growth the number of deceased donors been witnessed.After introduction Organ Transplant Act, which was enacted 2000, transparency established allocation Korea. However, donor dwindled significantly from 162 1999 to 36 2002. To improve donation, several strategies were...
The tumor biology of hepatocellular carcinoma (HCC) affects recurrence after liver transplantation (LT), but most selection guidelines are based only on size and number. aim the study is to evaluate possibility expanding criteria in living donor LT (LDLT) without compromising patient survival by adding alpha-fetoprotein (AFP) guideline.One hundred thirty-nine patients who received LDLT with diagnosis HCC survived more than 3 months were enrolled. operability was Milan beyond performed when...
QuantiFERON-TB Gold Plus (QFT-Plus) is a new-generation In-Tube (QFT-GIT) assay which has two antigen-coated tubes called TB1, contains long peptides derived from ESAT-6 and CFP-10, TB2, the same components as TB1 additional short potentially stimulate CD8 + T cells through presentation of major histocompatibility complex class I. This first study to compare QFT-Plus QFT-GIT for use in diagnosis latent tuberculosis infection (LTBI) among immunocompromised patients Republic Korea.
Induction of antigen-specific T cell tolerance would aid treatment diverse immunological disorders and help prevent allograft rejection graft versus host disease. In this study, we establish a method inducing in situ diabetic humanized mice Rhesus monkeys receiving porcine islet xenografts. Antigen-specific is induced by administration an antibody ligating particular epitope on ICAM-1 (intercellular adhesion molecule 1). Antibody-mediated ligation dendritic cells (DCs) led to the arrest DCs...
Donor kidney exchange is an established method to overcome incompatibility of donor–recipient pairs (DRP). A computerized algorithm was devised donor and tested in a multicenter setting. The made according the consensus participating centers. It makes all possible combinations not only between two incompatible DRP but also circularly among three selects optimum set combinations, considering several factors that can affect outcome exchanged transplant. implemented as web-based program,...
In Brief Purpose: To evaluate the clinical characteristics and prognosis of orbital invasive aspergillosis, a major cause morbidity mortality in immunocompromised patients. Methods: Review medical records Severance Hospital, Yonsei University College Medicine, from 1995 to 2007 revealed 15 patients with aspergillosis. A retrospective cohort study was conducted characteristics, radiologic findings, associated underlying diseases, prognosis. Risk factors for were analyzed. Results: total cases...
We performed this study to analyze the clinical features and prognosis of Korean patients with liposarcoma.Between October 1986 April 2013, 231 who were diagnosed liposarcoma by histologic examination enrolled in study.The distribution subtypes was well-differentiated (n = 97, 42%), myxoid 74, 32%), dedifferentiated 32, 13.9%), pleomorphic 15, 6.5%), round-cell 13, 5.6%). The majority liposarcomas located lower extremities (35.5%) retroperitoneum (34.2%). Prognosis worse for trunk group...
To evaluate the benefit of adjuvant radiation therapy (RT) for retroperitoneal liposarcoma (RPLS) following gross tumor removal.We reviewed 77 patients with primary RPLS surgically treated between January 2000 and December 2013. Cases residual disease were excluded. Tumor grade was evaluated according to French Federation Cancer Centers Sarcoma Group (FNCLCC) system. Adjuvant RT delivered 32 (42%) using external beam alone. Median follow-up time 36 months (range, 5 169).Among patients, 33...