A5024391498- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- Biochemical and Structural Characterization
- Trace Elements in Health
- Liver Disease Diagnosis and Treatment
- Hepatitis C virus research
- Malaria Research and Control
- Evolution and Genetic Dynamics
- Chemical Synthesis and Analysis
- Hepatitis B Virus Studies
- Child and Adolescent Health
- SARS-CoV-2 and COVID-19 Research
- Heavy metals in environment
- SARS-CoV-2 detection and testing
- Speech Recognition and Synthesis
- Heavy Metals in Plants
- Synthesis and pharmacology of benzodiazepine derivatives
- Radioactivity and Radon Measurements
- Molecular Sensors and Ion Detection
- Maternal Mental Health During Pregnancy and Postpartum
- Phytoplasmas and Hemiptera pathogens
- COVID-19 Clinical Research Studies
- Fuzzy Logic and Control Systems
- Organic Chemistry Synthesis Methods
- Microbial Natural Products and Biosynthesis
Burnet Institute
2023-2025
Goulburn Valley Health
2025
Australian Government
2024
Government of Western Australia Department of Health
2024
Breast Cancer Network Australia
2024
Rutgers, The State University of New Jersey
2022
Texas Biomedical Research Institute
2017-2021
University of Hawaii System
2014-2017
University of Hawaiʻi at Mānoa
2014
Sri Sathya Sai Institute of Higher Learning
2009
Do mutations required for adaptation occur de novo, or are they segregating within populations as standing genetic variation? This question is key to understanding adaptive change in nature, and has important practical consequences the evolution of drug resistance. We provide evidence that alleles conferring resistance oxamniquine (OXA), an antischistosomal drug, widespread natural parasite under minimal pressure predate OXA deployment. been used since 1970s treat Schistosoma mansoni...
Both theory and experimental data from pathogens suggest that the production of transmission stages should be strongly associated with virulence, but genetic bases parasite transmission/virulence traits are poorly understood. The blood fluke Schistosoma mansoni shows extensive variation in numbers cercariae larvae shed their virulence to infected snail hosts, consistent expected trade-offs between virulence. We crossed schistosomes two populations differ 8-fold cercarial shedding...
ABSTRACT Do mutations required for adaptation occur de novo , or are they segregating within populations as standing genetic variation? This question is key to understanding adaptive change in nature, and has important practical consequences the evolution of drug resistance. We provide evidence that alleles conferring resistance oxamniquine (OXA), an antischistosomal drug, widespread natural parasite under minimal pressure predate OXA deployment. been used since 1970s treat Schistosoma...
Objectives: To compare serological evidence of prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection with linked disease 2019 (COVID-19) case notification data in Victoria, Australia, and to determine vitro SARS-CoV-2 neutralisation activity based on vaccination history. Design, setting, participants: Four cross-sectional surveys were conducted between 30 June 31 October 2022 (a period Omicron BA.4/BA.5 dominance) using 1,974 residual serum samples obtained from the...
Organization and composition of the plasma membrane are important modulators many cellular programs. Phosphatidylinositol phosphate (PIP) lipids low abundance constituents with different arrangements groups around an inositol head group that regulate a large number signaling pathways. Many strategies have been developed to detect track PIP species monitor their clustering, mobility, interaction binding partners. We implement peptide-based ratiometric sensor for detection PI(4,5)P2 in...
Audio source separation, utilized for speech denoising and music production, involves extracting individual sources from a mixed track. The project goal was to reduce training times separation models with limited computing resources while improving accuracy, measured through signal-to-distortion ratio (SDR) signal-to-interference (SIR). We replaced the Bi-directional Long Short-Term Memory (BiLSTM) block transformer in open-source Open-Unmix model, it on MUSDB18-HQ dataset. Ultimately,...
Abstract Review: 116 refs.
ABSTRACT Both theory and experimental data from pathogens suggest that the production of transmission stages should be strongly associated with virulence, but genetic bases parasite transmission/virulence traits are poorly understood. The blood fluke Schistosoma mansoni shows extensive variation in numbers cercariae larvae shed their virulence to infected snail hosts, consistent expected trade-offs between virulence. We crossed schistosomes two populations differ 8-fold cercarial shedding...