A5053615380- Vibrio bacteria research studies
- Viral gastroenteritis research and epidemiology
- Vaccine Coverage and Hesitancy
- Child Nutrition and Water Access
- Escherichia coli research studies
- COVID-19 epidemiological studies
- Salmonella and Campylobacter epidemiology
- Pediatric health and respiratory diseases
- Antibiotic Resistance in Bacteria
- Blood groups and transfusion
- Wound Healing and Treatments
- Burn Injury Management and Outcomes
- COVID-19 and Mental Health
- COVID-19 and healthcare impacts
- Antibiotics Pharmacokinetics and Efficacy
- Injury Epidemiology and Prevention
- Reconstructive Surgery and Microvascular Techniques
- Hepatitis B Virus Studies
- SARS-CoV-2 and COVID-19 Research
- Agriculture, Water, and Health
- Renal cell carcinoma treatment
- Complementary and Alternative Medicine Studies
- Economic and Financial Impacts of Cancer
- Anorectal Disease Treatments and Outcomes
- Artificial Intelligence in Healthcare and Education
Dhaka Medical College and Hospital
2014-2020
International Centre for Diarrhoeal Disease Research
1984-1995
University of Gothenburg
1986-1991
University of Maryland, Baltimore
1990-1991
Johns Hopkins University
1986-1991
Centers for Disease Control and Prevention
1987-1991
Eunice Kennedy Shriver National Institute of Child Health and Human Development
1991
The Centers
1990
Bangladesh University
1984
Journal Article Cross-Protection by B Subunit-Whole Cell Cholera Vaccine Against Diarrhea Associated with Heat-Labile Toxin-Producing Enterotoxigenic Escherichia coli: Results of a Large-Scale Field Trial Get access John D. Clemens, Clemens 1Please address requests for reprints to Dr. International Centre Diarrhoeal Disease Research, Bangladesh, G.P.O. Box 128, Dhaka-1000, Bangladesh. Search other works this author on: Oxford Academic PubMed Google Scholar David A. Sack, Sack Jeffrey R....
We performed a prospective study to examine whether the IgA antibodies against cholera that are present in breast milk protect breast-fed infants and children colonization with Vibrio cholerae 01 disease. Among families of patients cholera, we collected from mothers who had not diarrhea previous week monitored them their for 10 days. Breast was assayed toxin lipopolysaccharide. Ninety-three mother--child pairs were studied; 30 became colonized V. disease developed 19. There no differences...
At the Matlab Hospital of international Centre for Diarrhoeal Disease Research, Bangladesh, authors examined blood groups patients hospitalized between January and September 1979 diarrheal disease due to a variety bacterial viral agents. A significant association was identified only cholera, in which cholera were twice as likely have group O one-ninth AB community controls. follow-up study family contacts patients, carried out 1980 July 1982, indicated that did not affect an individual's...
Journal Article Seroepidemiological Studies of EI Tor Cholera in Bangladesh: Association Serum Antibody Levels with Protection Get access Roger I. Glass, Glass Search for other works by this author on: Oxford Academic PubMed Google Scholar Ann-Mari Svennerholm, Svennerholm M. R. Khan, Khan Shamsul Huda, Huda Imdadul Huq, Huq Jan Holmgren The Infectious Diseases, Volume 151, Issue 2, February 1985, Pages 236–242, https://doi.org/10.1093/infdis/151.2.236 Published: 01 1985 history Received: 18...
We assessed the protective efficacy (PE) of three doses B subunit-killed whole cell (BS-WC) and killed cell-only (WC) oral cholera vaccines in a randomized, double-blind trial among 62 285 children women residing rural Bangladesh. After one complete year surveillance, 110 cases were detected placebo group, 52 we group (PE, 53%; P < .0001), 41 BS-We 62%; .0001). Protection was greater for BS-WC recipients than only during initial eight months observation. Both conferred equivalent protection...
Journal Article ABO Blood Groups and Cholera: New Observations on Specificity of Risk Modification Vaccine Efficacy Get access John D. Clemens, Clemens Please address requests for reprints to Dr. Center Development, University Maryland School Medicine, 10 South Pine Street, Baltimore, MD 21201. Search other works by this author on: Oxford Academic PubMed Google Scholar David A. Sack, Sack Jeffrey R. Harris, Harris J. Chakraborty, Chakraborty M. Khan, Khan S. Huda, Huda Faruque Ahmed, Ahmed...
Hossain M (International Centre for Diarrhoeal Disease Research, GPO Box 128, Dacca-2, Bangladesh), Glass R I and Khan R. Antibiotic use in a rural community Bangladesh. International Journal of Epidemiology 1982, 11: 402–405. by 175 000 people the Matlab surveillance area (MSA) Bangladesh (ICDDR,B) was studied to identify practices which might affect microbial drug resistance. We surveyed 3% sample purchases from pharmacies MSA over four-week period August September 1980. Fifty-seven were...
Journal Article B Subunit-Whole Cell and Whole Cell-Only Oral Vaccines Against Cholera: Studies on Reactogenicity Immunogenicity Get access John D. Clemens, Clemens From the International Centre for Diarrhoeal Disease Research, Bangladesh; University of Göteborg, Sweden; Enteric Branch, Centers Control, Atlanta, Georgia; Division Geographic Medicine, Johns Hopkins Univeristy, Baltimore, Maryland Please address requests reprints to Dr. G.P.O. Box 128, Dhaka 2, Bangladesh. Search other works...
The relationship of serum vibriocidal (VC) and IgG anti-cholera toxin(CT)antibodies to the risk cholera was evaluated during first year follow-up recipients three oral doses B subunit (BS)-whole-cell vaccine, whole-cell or Escherichia coli K12 strain placebo in Bangladesh. Acute sera from 121 patients were comparedwith 2592 contemporaneous community controls. Each doubling VC titer associated, on average, with a 22%–47% reductionof groups. In contrast, two groups that did not receive BS,...
Colistin is a last-resort antimicrobial for treating multidrug-resistant Gram-negative bacteria. Phenotypic colistin resistance highly associated with plasmid-mediated mobile (mcr) genes. mcr-bearing Enterobacteriaceae have been detected in many countries, the emergence of colistin-resistant pathogens global concern. This study assessed distribution mcr-1, mcr-2, mcr-3, mcr-4, and mcr-5 genes phenotypic isolates from diarrheal infants children Bangladesh. Bacteria were identified using...
Background: The incidence of renal cell carcinoma (RCC) is increasing worldwide. aims this study were to describe epidemiological data, risk factors, clinicopathological characteristics RCC. Methods: This cross-sectional descriptive was carried out at the department Urology, BIRDEM General Hospital from Janaury 2013 July 2023. All radiological and fine needle aspiration (FNA) positive RCC cases included othere tumor such as angiolipoma, cyst, tuberculosis excluded. Results: A total 200...
Journal Article BREAST FEEDING AND THE RISK OF SEVERE CHOLERA IN RURAL BANGLADESHI CHILDREN Get access JOHN D. CLEMENS, CLEMENS 1International Centre for Diarrhoeal Disease ResearchBangladesh, Dhaka, Bangladesh2Center Vaccine Development, University of Maryland School MedicineBaltimore, MD Reprint requests to Dr. John Clemens, Center Medicine, 10 S. Pine Street, Baltimore, 21201 Search other works by this author on: Oxford Academic PubMed Google Scholar DAVID A. SACK, SACK Bangladesh3Johns...
In 1979, an outbreak of plasmid-borne, multiply drug-resistant Vibrio cholerae serogroup O1 biotype El Tor (V. O1) occurred in the Matlab area Bangladesh. The could have resulted from introduction into a single resistant strain or multiple conjugations drug-sensitive V. with C plasmids other environmental flora. Resistant strains were phage typed to determine their relatedness, and plasmid studies conducted frequency nonvibrio flora family contacts cholera patients. Forty-one (85%) 48...
Journal Article Effect of Neutralization Gastric Acid on Immune Responses to an Oral B Subunit, Killed Whole-Cell Cholera Vaccine Get access J. D. Clemens, Clemens International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh; the University Göteborg, Sweden; and Division Geographic Medicine, Johns Hopkins University, Baltimore, Maryland Please address requests reprints Dr. John GPO Box 128, Dhaka-2, Bangladesh. Search other works by this author on: Oxford Academic...
Abstract: Colistin is a last-resort antimicrobial for treating multidrug-resistant Gram-negative bacteria. Phe-notypic colistin resistance highly associated with plasmid-mediated mobile (mcr) genes. mcr-bearing Enterobacteriaceae have been detected in many countries, the emergence of colistin-resistant pathogens global concern. This study assessed distribution mcr-1, mcr-2, mcr-3, mcr-4, and mcr-5 genes phenotypic isolates from diarrheal infants children Bangladesh. Bacteria were identified...
To assess the association between breast-feeding and risk of microbiologically confirmed or clinically presumptive shigellosis, authors performed a case-control analysis Bangladeshi children younger than 3 years age who were followed up for 1 month after exposure to Shigella in their residential neighborhoods. Two hundred sixty-nine cases with culture-confirmed shigellosis (n = 119) (culture-negative dysentery, n 150) compared 819 controls without diarrhea other invasive diarrheal illnesses....
Sera collected during the 1985 oral cholera vaccinetrial in Matlab, Bangladesh, which demonstrated efficacyof a whole cell combined with B subunit vaccine (WC/BS) and only (WC), were analyzed for antitoxin vibriocidal antibodies. Before vaccines given, titers highest children, especially those 0 blood group, whereas rose throughout life.Two weeks after three doses of vaccine, geometric mean 2.5–4.5 times higher vaccinees who received WelBS vaccine; 1.3–2.1 vaccineeswho receivedeither...
Introduction Burns are most prevalent in low- and middle-income countries but the risk factors for burn contractures these settings poorly understood. There is some evidence from country studies to suggest that non-medical such as socio-economic health system issues may be as, or possibly more, important than biomedical development of post-burn contractures. Methods Four cases presented illustrate impact non-biomedical on contracture outcomes a low-income setting. The were drawn participants...
In a randomized, placebo-controlled field trial of B subunit-killed whole cell (BS-WC) and killed only (WC) inactivated oral cholera vaccines in rural Bangladesh, active surveillance selected neighborhoods during the first year after vaccination identified 127 Vibrio cholerae O1 infections among 3285 three-dose recipients. For each vaccine, protective efficacy was greater against symptomatic (57%, P < .05 for BS-WC; 58%, WC) than asymptomatic (46%, 32%, = .09 WC), protection grade infection...