- Escherichia coli research studies
- Salmonella and Campylobacter epidemiology
- Viral gastroenteritis research and epidemiology
- Bacteriophages and microbial interactions
- Antibiotic Resistance in Bacteria
- Bacterial Genetics and Biotechnology
- Clostridium difficile and Clostridium perfringens research
- Vibrio bacteria research studies
- Enterobacteriaceae and Cronobacter Research
- Listeria monocytogenes in Food Safety
- Aquaculture disease management and microbiota
- Probiotics and Fermented Foods
- Food Safety and Hygiene
- Animal Virus Infections Studies
- Genomics and Phylogenetic Studies
- Microbial infections and disease research
- Travel-related health issues
- Cancer Research and Treatments
- Identification and Quantification in Food
- Infant Nutrition and Health
- Mycobacterium research and diagnosis
- Veterinary medicine and infectious diseases
- Animal Nutrition and Physiology
- Bacterial Infections and Vaccines
- Monoclonal and Polyclonal Antibodies Research
National Public Health Laboratory
1988-1999
Central Middlesex Hospital
1971-1998
Public Health Laboratory
1980-1998
Public Health England
1990-1998
Brigham and Women's Hospital
1997
International Centre for Diarrhoeal Disease Research
1983-1995
University of Ruhuna
1993
Alexandria University
1975-1993
The University of Texas Health Science Center at Houston
1993
University of Gothenburg
1988-1990
SUMMARY Over the past 5 years Salmonella enteritidis infections in humans have increased on both sides of Atlantic ocean. The WHO salmonella surveillance data for 1979–87 were reviewed and show that S. appears to be increasing at least continents North America, South Europe, may include Africa. isolates 24 (69%) 35 countries between 1979 1987. In 1979, only 2 (10%) 21 with reported as their most common serotype; 1987, 9 (43%) 8 (89 %) European countries. Although reason global increase is...
For many years phage typing has proved invaluable in epidemiological studies on Salmonella typhi, S. paratyphi A and B, typhimurium a few other serotypes. phage-typing scheme for enteritidis is described. This to date differentiates 27 types using 10 phages.
SUMMARY Over 5700 hens eggs from 15 flocks naturally infected with Salmonella enteritidis were examined individually for the presence of organism in either egg contents or on shells. Thirty-two (0·6%) positive contents. In majority, levels contamination low. Three eggs, however, found to contain many thousands cells. where it was possible identify site contamination, albumen more frequently than yolk. Storage at room temperature had no significant effect prevalence salmonella-positive but...
Sixteen cases of verotoxin producing Escherichia coli (VTEC) O 157:H7 Phage Type 49 infection were identified in the North West England from 1 September to November 1991, eight whom lived or around same large town. Eleven aged 10 years less, and five affected children developed haemolytic uraemic syndrome. A case control study demonstrated a strong association between VTEC PT consumption locally produced live yoghurt. This is first time that an outbreak 157 has been linked yoghurt this...
Two small flocks of egg-laying hens, naturally infected with Salmonella enteritidis, were housed in individual cages so that their eggs could be identified. During a longitudinal study where the contents 1,119 examined, 11 positive for S. enteritidis. One isolate was phage type (PT) 33 others PT4. The production clustered though intermittent. eggs, which produced by 10 35 all found to contain fewer than salmonellas. Some birds also apparently carrying hadar PT14 as this organism isolated...
In Salmonella typhimurium phage type 204c isolated in Britain, gentamicin resistance is specified by plasmids of the I1 compatibility group which also confer to apramycin. These have been subdivided into three types within on basis their antibiotic specificity, ability produce colicin Ib and restriction enzyme digest fragmentation patterns. All identified strains from cattle, but as yet only two found humans. It suggested that use apramycin animal husbandry responsible for appearance...
In a three year study of children under 16 years with haemolytic uraemic syndrome faecal samples were examined for the presence Verocytotoxin producing Escherichia coli (VTEC) using DNA probes and free neutralisable in Vero cell assay specific antisera. There was evidence VTEC infection 58 185 (31%) samples. A total 53 identified from patients syndrome. Thirty eight belonged to serotype O157:H7 or O157:H-, 34 produced VT2 only, four strains both VT1 VT2. The remaining 15 nine different O...
Phages coding for production of Vero cytotoxins VT1 or VT2 in strains Escherichia coli serotype O157. H7 H− were morphologically indistinguishable. Their genome size and restriction enzyme digests the phage DNA similar. These phages clearly different these respects from a VT1-encoding isolated strain E. O26. H11 (H19). However region cloned originating was identical to previously carried by H19. Sequences encoding that have been mapped identified transposon insertion. The regions had no...
OBJECTIVE--To determine the source of indigenous sporadic infection with Salmonella enteritidis phage type 4. DESIGN--Case-control study primary cases identified by Public Health Laboratory Service between 1 August and 30 September 1988. SETTING--PHLS Communicable Disease Surveillance Centre, Division Enteric Pathogens, 11 PHLS laboratories, 42 local authority environmental health departments in England. SUBJECTS--232 Patients (cases) confirmed infection, for 160 whom (88 female) (median age...
Summary. Faecal specimens from 66 children with haemolytic uraemic syndrome in the United Kingdom were examined for strains of Escherichia coli producing Vero cytotoxin (VT). Initially, conventional bacteriological methods used to identify colonies E. which then tested VT production. Subsequently, specific DNA probes VT1 and VT2 hybridisation tests detect VT-producing (VTEC). VTEC isolated 19 cases 15 they belonged serogroup O157. Fourteen these O157 possessed flagellar antigen H7 one was...
A prospective study of the clinical and epidemiological features haemolytic uraemic syndromes was conducted over a three year period in British Isles. Two hundred ninety eight children were reported. In two thirds cases stool samples analysed for presence Verocytotoxin producing Escherichia coli (VTEC) neutralisable Verocytotoxin. total 273 (95%) patients had prodrome diarrhoea. these seasonal variation incidence syndrome demonstrated, 1-2 age range most often affected, peripheral blood...
Five bacteriophage stocks were prepared after enrichment of a sewage sample using Escherichia coli 02:K1:H4 (strain U9/41). The bacteriophages tested for their ability to lyse 224 strains E. that had been the presence K1 antigen by means an antiserum-agar diffusion technique, meningococcus group B antiserum known detect antigen. standard test K antigens 2 99 used as control strains. Of 101 found possess 93 lysed at least one bacteriophages, whereas 8 123 apparently lacking or more...
<h3>Abstract</h3> <b>Objectives</b>: To identify the source of an international outbreak food poisoning due to Salmonella agona phage type 15 and measure how long underlying cause persisted. <b>Design</b>: Case-control study 16 primary household cases 32 controls similar age dietary habit. Packets implicated foodstuff manufactured on a range days were examined for salmonella. All isolates epidemic further characterised by pulsed field gel electrophoresis. <b>Results</b>: 27 identified, which...
In March 1988, there was an outbreak of infection by a strain Salmonella saint-paul with distinctive antigenic marker. A total 143 reports were received between 1 and 7 June. Preliminary investigations suggested that raw beansprouts possible source case-control study confirmed the association. S. epidemic type isolated from samples on retail sale in different cities United Kingdom mung bean seeds premises producer who most strongly associated cases. addition, virchow PT34 subsequently seven...