A5049597905- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiomyopathy and Myosin Studies
- Atrial Fibrillation Management and Outcomes
- Microbial Inactivation Methods
- Diamond and Carbon-based Materials Research
- Neurological disorders and treatments
- Cardiac Structural Anomalies and Repair
- Analog and Mixed-Signal Circuit Design
- Electrohydrodynamics and Fluid Dynamics
- Pericarditis and Cardiac Tamponade
- Electrostatic Discharge in Electronics
- Laser Design and Applications
- Wireless Sensor Networks for Data Analysis
- Innovation Policy and R&D
- Health Systems, Economic Evaluations, Quality of Life
- Kawasaki Disease and Coronary Complications
- Plasma Applications and Diagnostics
- Cardiac Valve Diseases and Treatments
- Coronary Artery Anomalies
- Cardiovascular Effects of Exercise
Hoag Memorial Hospital Presbyterian
2015-2025
University of California, Irvine Medical Center
2015-2017
Michigan State University
2017
Newport (United States)
2016
San Francisco General Hospital
2010
University of California, San Francisco
2010
California Pacific Medical Center
2009
Cardiac pacemakers are limited by device-related complications, notably infection and problems related to pacemaker leads. We studied a miniaturized, fully self-contained leadless that is nonsurgically implanted in the right ventricle with use of catheter.In this multicenter study, we an active-fixation cardiac patients who required permanent single-chamber ventricular pacing. The primary efficacy end point was both acceptable pacing threshold (≤2.0 V at 0.4 msec) sensing amplitude (R wave...
The effect of contact force (CF) on lesion formation is not clear during pulsed field ablation (PFA). aim this study was to evaluate the impact CF, PFA, and their interplay through PFA index (PF index) formula ventricular size in swine.
There are limited comparative data on catheter ablation of atrial fibrillation (CAAF) using the second-generation cryoballoon (CB-2) versus point-by-point radiofrequency (RF). This study examines acute/long-term CAAF outcomes these 2 strategies.In this multicenter, retrospective, nonrandomized analysis, procedural and clinical 1,196 patients (76% with paroxysmal AF) undergoing CB-2 (n = 773) open-irrigated, non-force sensing RF 423) were evaluated. Pulmonary vein isolation was achieved in...
Background: Leadless pacemakers (LPs) can mitigate conventional pacemaker complications related to the transvenous leads and subcutaneous pocket surrounding pulse generator. Although single-chamber leadless pacing has been established, multichamber requires wireless bidirectional communication across multiple LPs maintain synchrony. This preclinical study demonstrates chronic performance of implant-to-implant (i2i) that achieves synchronous, dual-chamber with 2 LPs. Methods: The i2i modality...
Pulsed-field ablation (PFA), an ablative method that causes cell death by irreversible electroporation, has potential safety advantages over radiofrequency and cryoablation. Pulmonary vein (PV) isolation was performed in a porcine model to characterize performance of novel, fully-integrated biphasic PFA system comprising multi-channel generator, variable loop circular catheter, integrated mapping software module.Eight healthy subjects were included. To evaluate safety, multiple ablations...
The clinical utilization of leadless pacemakers (LPs) as an alternative to traditional transvenous is likely increase with the advent dual-chamber LP systems. Since device retrieval allow upgrade or replacement will become important capability, first such dual-chamber, helix-fixation system (Aveir DR; Abbott, Abbott Park, IL) was specifically designed catheter-based retrieval. In this study, preclinical performance and safety retrieving chronically implanted LPs evaluated.
Key Teaching Points•Compared to conventional pacemaker systems, pacing thresholds in the Nanostim leadless showed greater magnitude of improvement threshold.•Even if an initial threshold is high, a longer waiting period may lead significant reduction threshold.•The unique behavior system likely owing difference size helix and position anode compared traditional active-fixation transvenous leads. •Compared
Purpose: Leadless pacemakers (LPs) are miniaturized, fully self-contained devices percutaneously implanted in the right ventricle using a femoral vein approach. The multicenter LEADLESS II clinical trial has demonstrated that both pre-specified safety and effectiveness endpoints for NanostimTM LP were met. This study assessed health-related quality-of-life (HRQoL) these patients its corresponding changes over time. Method: Patients' HRQoL EuroQol EQ-5D, preference-based instrument from which...
Background: The Nanostim {trade mark, serif} Leadless Cardiac Pacemaker (LCP) has been shown to be safe and effective in human clinical trials. Since there is little information on the effect of implant location LCP performance, aim this study was determine whether anatomic position affects long-term pacing performance LCP. Methods: Patients who enrolled II IDE Clinical Trial had finished 6 months follow up (n = 479) were selected for study. implanting investigators determined final under...
fects of CRT in patients affected by a valvular heart disease, but on the basis "real world" clinical practice, appears more effective DCM than VHD.