A5087164895- Food Allergy and Anaphylaxis Research
- Allergic Rhinitis and Sensitization
- Asthma and respiratory diseases
- Transgenic Plants and Applications
- Immunodeficiency and Autoimmune Disorders
- Tracheal and airway disorders
- Celiac Disease Research and Management
- Viral gastroenteritis research and epidemiology
- Respiratory viral infections research
- Herpesvirus Infections and Treatments
- Respiratory and Cough-Related Research
- Toxin Mechanisms and Immunotoxins
Inserm
2023-2024
Université de Toulouse
2023-2024
Centre National de la Recherche Scientifique
2023-2024
Centre d’Investigation Clinique 1436
2024
Hôpital des Enfants
2020-2023
Hôpital Purpan
2023
Centre Hospitalier Universitaire de Toulouse
2020
Respiratory syncytial virus (RSV) is the leading cause of bronchiolitis, resulting in 3 million hospitalizations each year worldwide. Nirsevimab a monoclonal antibody against RSV that has an extended half-life. Its postlicensure real-world effectiveness RSV-associated bronchiolitis unclear.
BackgroundDespite their central role in peanut allergy, human monoclonal IgE antibodies have eluded characterization.ObjectiveWe sought to define the sequences, affinities, clonality, and functional properties of allergy.MethodsWe applied our single-cell RNA sequencing–based SEQ SIFTER discovery platform samples from allergic individuals who varied by age, sex, ethnicity, geographic location order understand commonalities response allergens. Select were then recombinantly expressed...
ABSTRACT Background Diagnosis of allergies is mostly based on the patient's clinical history and allergen provocation tests. Determination specific IgE (sIgE) profiles can be performed to support allergy diagnosis. This commonly done in vivo by skin prick test or vitro with automated systems. Several platforms exist quantify sIgE levels, but all these methods require access instruments, often delaying test's results. The luciferase‐linked immunosorbent assay (LuLISA) allows bioluminescent...
Background: Oral immunotherapy (OIT) seems to be a promising treatment for hazelnut allergy but the available data is limited. Our objective was evaluate proportion of patients desensitised after OIT, as well and type adverse events (AEs) occurring during OIT identify clinical biological factors predictive success. Methods: Single-center retrospective study, including pediatrics patients. food challenge (OFC) performed before OIT. For each patient, we collected level IgEs f17, nCor 9, rCor...