Chenyang Zhu

ORCID: 0009-0008-3218-1543
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About
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Research Areas
  • Perovskite Materials and Applications
  • Conducting polymers and applications
  • Chalcogenide Semiconductor Thin Films
  • Machine Learning in Materials Science
  • Pharmacological Effects of Natural Compounds
  • Fungal Biology and Applications
  • Botanical Studies and Applications
  • Organic Electronics and Photovoltaics
  • Sperm and Testicular Function
  • Cancer-related Molecular Pathways
  • Reproductive System and Pregnancy
  • Diabetes Treatment and Management
  • Gut microbiota and health
  • Cardiac Valve Diseases and Treatments
  • RNA modifications and cancer
  • Cardiac Health and Mental Health
  • Cancer-related gene regulation
  • Bone Metabolism and Diseases
  • Reproductive Biology and Fertility
  • Microbial Metabolic Engineering and Bioproduction
  • Metabolomics and Mass Spectrometry Studies
  • Phytochemistry and Bioactive Compounds
  • Organic Light-Emitting Diodes Research
  • Diabetes Management and Research
  • Cardiovascular Function and Risk Factors

Fudan University
2023-2025

Fujian University of Traditional Chinese Medicine
2025

Hangzhou Dianzi University
2024

Zhejiang University
2024

Dalian Medical University
2015-2017

Harbin Veterinary Research Institute
2017

Chinese Academy of Agricultural Sciences
2017

Northeast Agricultural University
2017

Hawthorn leave flavonoids (HLF) are widely used as an herb or dietary supplements for cardio-cerebrovascular diseases. However, its gastrointestinal absorption behavior and mechanism have not been disclosed. In this study, regulation of 4''-O-glucosylvitexin (GLV), 2''-O-rhamnosylvitexin (RHV), vitexin (VIT), rutin (RUT) hyperoside (HP) in HLF were investigated using vitro, situ vivo models. Apparent permeability coefficient (Papp) five (2.18 ± 0.15) ×10−7~(3.83 0.22) ×10−7 cm·sec−1 across...

10.1038/s41598-024-81823-y article EN cc-by-nc-nd Scientific Reports 2025-01-03

Background/Aims: Osteopontin (OPN) is an Extracellular Matrix (ECM) molecule and involved in many physiologic pathologic processes, including cell adhesion, angiogenesis tumor metastasis. OPN a well-known multifunctional factor various aspects of cancer progression, endometrial cancer. In this study, we examined the significance Methods: The proliferation, migration invasion ability HEC-1A cells were detected by Cell Counting Kit-8 (CCK-8), Wound scratch assay transwell. Western blots...

10.1159/000438518 article EN cc-by-nc Cellular Physiology and Biochemistry 2015-01-01

p53 dysfunction is frequently observed in lung cancer. Although restoring the tumour suppressor function of recently approved as a putative strategy for combating cancers, lack understanding molecular mechanism underlying p53-mediated cancer suppression has limited application p53-based therapies cancer.Using RNA sequencing, we determined transcriptional profile human non-small cell carcinoma A549 cells after treatment with two p53-activating chemical compounds, nutlin and RITA, which could...

10.1159/000478873 article EN cc-by-nc-nd Cellular Physiology and Biochemistry 2017-01-01

Adjusting the hole transport layer (HTL) to optimize its interface with perovskite is crucial for minimizing recombination, enhancing carrier extraction, and achieving efficient stable inverted solar cells (PSCs). However, as a commonly used HTL, self-assemble (SAM) of [2-(3,6-dimethoxy-9H-carbazol-9-yl)ethyl] phosphonic acid (MeO-2PACz) tends form clusters micelles during deposition process, leading inadequate coverage ITO substrate. Here, Co-SAM strategy employed by incorporating...

10.1002/smll.202408314 article EN Small 2024-11-17

Due to the unique characteristics of solution preparation and rapid crystal growth, perovskite solar cells (PSCs) may exhibit various kinds defects that ultimately impact their photovoltaic performance. Here, a multifunctional additive potassium trifluoromethanesulfonate (KTFS) was introduced into lead iodide (PbI2) precursor solution, where strong electron-donating sulfonyl group tends bond with has significant inhibitory effect on Pb0 halogen vacancies. Benifiting from these, formation...

10.2139/ssrn.4693118 preprint EN 2024-01-01

Ethnophamacological relevanceHawthorn leave flavonoids (HLF) derived from traditional herb hawthorn leave, is widely used as an herbal medicine or dietary supplements for the treatment of cardio-cerebrovascular diseases in some countries such China. However, behavior and mechanism gastrointestinal absorption HLF are hardly been disclosed up to now, which limits its development application.Aim studyThe study was aimed investigated HLF.Materials methodsIn this study, Caco-2 cell experiment,...

10.2139/ssrn.4805414 preprint EN 2024-01-01

Oritavancin is a new generation of semi-synthetic glycopeptide antibiotics against Gram-positive bacteria, which served as the first and only antibiotic with single-dose therapeutic regimen to treat ABSSSI. A naturally occurring A82846B direct precursor oritavancin. However, its application has been hampered by low yields homologous impurities. This study established multi-step combinatorial strategy rationally construct high-quality high-efficiency biosynthesis system for systematically...

10.1186/s12934-024-02464-4 article EN cc-by Microbial Cell Factories 2024-06-28

The buried interface in inverted perovskite solar cells (PSCs) is critical for determining device performance. However, during annealing, the crystallized downward from film's top surfaces, and use of dimethyl sulfoxide (DMSO) often resulted voids at bottom surface, which negatively impacted PSC In this study, a green solid-state additive, piracetam (PA), was introduced into precursor to reduce void formation. Due stronger interaction with components than DMSO, nonvolatile PA could remain...

10.1021/acsami.4c15597 article EN ACS Applied Materials & Interfaces 2024-11-18

Highlights•Comprehensive database of training models•Explainable models are used to predict the PCE organic solar cells•Three non-fullerene acceptor molecules were designed based on SHAP analysis•The error between model prediction and experimental verification is less than 3%SummaryThe power conversion efficiency (PCE) cells (OSCs) has exceeded 19% with development acceptors (NFAs). Here, machine learning (ML) inputs both molecular descriptors fingerprints different algorithms investigated...

10.1016/j.xcrp.2024.102316 article EN cc-by Cell Reports Physical Science 2024-12-01

This study assessed the feasibility of using LeY glycan secretion level in human embryos as a method judging embryo quality. Embryo culture media from patients receiving vitro fertilization-embryo transfer was collected, and quality scores were recorded. Secretions different development stages (from 4-cell to 10-cell), same stage (8-cell/I) examined by dot-blot. Embryos divided into hypersecretion group hyposecretion group, based on their level. The evaluated clinical observations, number...

10.3892/etm.2017.4495 article EN Experimental and Therapeutic Medicine 2017-05-22
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