Li Xiu

ORCID: 0009-0008-4823-9025
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Research Areas
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Gut microbiota and health
  • Metal complexes synthesis and properties
  • Diet and metabolism studies
  • Traditional Chinese Medicine Studies
  • Medical Research and Treatments
  • Parasite Biology and Host Interactions
  • Metal-Organic Frameworks: Synthesis and Applications
  • Pharmacological Effects of Natural Compounds
  • Ovarian function and disorders
  • Helminth infection and control
  • Catalytic C–H Functionalization Methods
  • Synthesis and Characterization of Heterocyclic Compounds
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Parasites and Host Interactions
  • Helicobacter pylori-related gastroenterology studies
  • Crystal structures of chemical compounds
  • CAR-T cell therapy research
  • Educational Reforms and Innovations
  • Magnetism in coordination complexes
  • Viral Infectious Diseases and Gene Expression in Insects
  • Synthesis and Catalytic Reactions
  • Mycobacterium research and diagnosis
  • Advancements in Battery Materials

Tiangong University
2025

Public Health Clinical Center of Chengdu
2024

Sixth Affiliated Hospital of Kunming Medical University
2018-2024

Kunming Medical University
2018-2024

Qingdao University
2011-2024

Qingdao Municipal Hospital
2024

Hefei First People's Hospital
2011-2024

Huazhong University of Science and Technology
2024

Jiangsu University
2023

South China University of Technology
2018-2023

A high-fat diet (HFD) can easily induce obesity and change the gut microbiota its metabolites. However, studies on effects of diets host have drawn inconsistent results. In this study, unexpected results showed that refined HFD increased diversity short-chain fatty acids (SCFAs), causing an increase in energy metabolism. Further analysis revealed these changes were caused by different fiber content two diets. Male C57BL/6J mice (4–5 weeks old) fed either or low-fat (LFD) for 14 weeks. The...

10.3390/nu12103197 article EN Nutrients 2020-10-20

Summary S‐adenosyl‐ l ‐methionine ( SAM ) synthetase is the key enzyme involved in biosynthesis of , which serves as a common precursor for polyamines PA s) and ethylene. A cDNA SlSAMS1 was introduced into tomato genome using Agrobacterium tumefaciens transformation method. Transgenic plants overexpressing exhibited significant increase tolerance to alkali stress maintained nutrient balance, higher photosynthetic capacity lower oxidative compared with WT lines. Both vivo vitro experiments...

10.1111/pbi.12173 article EN other-oa Plant Biotechnology Journal 2014-03-07

LAB exhibiting hypoglycaemic effects reduced insulin resistance by contributing to the production of SCFAs and alleviation inflammation. <italic>L. rhamnosus</italic> regulated blood lipid more efficiently than <italic>Bifidobacterium</italic>.

10.1039/c9fo02761k article EN Food & Function 2020-01-01

Abstract High‐voltage sodium metal batteries exhibit excellent advantages in low cost and high energy density. However, the poor compatibility of traditional electrolyte with (Na) anode high‐voltage cathode leads to interfacial instability potential flammable risks. In this work, a nonflammable is developed address cycling stability 4.7 V battery by constructing electrode–electrolyte interphases perchlorate (NaClO 4 ) additive. The NaClO additive not only enables efficient Na...

10.1002/adfm.202500258 article EN Advanced Functional Materials 2025-03-05

Administration of certain lactic acid bacteria alleviate polycystic ovarian syndrome in a letrozole induced rat model.

10.1039/c9fo02554e article EN Food & Function 2020-01-01

Cardiovascular disease has one of the highest global incidences and mortality rates. Atherosclerosis is main cause cardiovascular disease, hypercholesterolaemia hyperlipidaemia are risk factors for development atherosclerosis. Decreasing serum cholesterol triglyceride concentrations considered to be an effective strategy prevent atherosclerotic disease. Previous studies have shown that many diseases related gut microbiota dysbiosis. The positive regulation by probiotics may or treat certain...

10.3390/nu14061272 article EN Nutrients 2022-03-17

Abstract It has been reported that remarkable and sustained activation of astrocytes and/or microglia occurs in cancer induced pain (CIP), which is different from neuropathic inflammatory pain. The present study was designed to investigate the role spinal Toll-like receptor 4 (TLR4) glial neuroinflammation using a modified rat model bone cancer. CIP consisted unilateral intra-tibial injection with Walker 256 mammary gland carcinoma. Nine days after inoculation, robust both bilateral dorsal...

10.1186/1756-6606-5-16 article EN cc-by Molecular Brain 2012-05-20

The incidence of obesity, which is closely associated with the gut microbiota and chronic inflammation, has rapidly increased in past 40 years. Therefore, probiotic-based modification intestinal composition been developed as a strategy for treatment obesity. In this study, we selected four Bifidobacterium adolescentis strains isolated from feces newborn elderly humans to investigate whether supplementation B. various origins could alleviate obesity mice. Male C57BL/6J mice fed high-fat diet...

10.3390/nu13031017 article EN Nutrients 2021-03-21

The decrease in ovarian hormone secretion that occurs during menopause results an increase body weight and adipose tissue mass. Probiotics soy isoflavones (SIFs) could affect the gut microbiota exert anti-obesity effects. objective of this study was to investigate effects probiotics a diet containing SIF (SIF diet) on ovariectomized mice with menopausal obesity, including microbiome. demonstrate

10.3390/nu13061793 article EN Nutrients 2021-05-25

To investigate chemotherapy dosage-related cognitive impairment and its neural mechanisms in breast cancer (BC) patients. Twenty-eight patients after each cycle matched 29 healthy control subjects underwent structural magnetic resonance imaging. Voxel-based morphometry analysis was performed to compare group differences the gray matter for whole brain. Furthermore, mediation conducted explore role of brain structures impairment. BC chemotherapy. The results revealed that density left...

10.1038/s41598-018-32257-w article EN cc-by Scientific Reports 2018-09-10

Polycystic ovary syndrome (PCOS) is an endocrine disorder that affects women of reproductive age.

10.1039/d1fo01744f article EN Food & Function 2022-01-01

Ferroelectrics with a perovskite structure, exhibiting strong coupling between photons, carriers, and phonons, have been demonstrated to show photostrictive response. Limited by the optical bandgap, most of reported ferroelectric perovskites respond only UV light or weakly visible below 550 nm. Herein, performance CaCu3Ti4O12 (CCTO) ceramics, low bandgap ∼1.5 eV (ideal for solar spectrum absorption), is comprehensively investigated. Although compound presents no ferroelectricity, in general,...

10.1063/1.5142882 article EN Applied Physics Letters 2020-03-16

Abstract Background Chimeric antigen receptor T (CAR-T) cells are genetically modified with redirected specificity and potent T-cell-mediated cytotoxicity toward malignant cells. Despite several CAR-T products being approved commercialized in the USA, Europe, China, still require additional optimization to ensure reproducible cost-effective manufacture. Here, we investigated critical parameters CD3 + T-cell isolation process that significantly impacted manufacturing's success. Methods were...

10.1186/s12967-022-03833-6 article EN cc-by Journal of Translational Medicine 2022-12-19

Platinum-based chemotherapies, historically the cornerstone of first-line treatment for small-cell lung cancer (SCLC), face a major hurdle: frequent emergence chemoresistance, notably to cisplatin (CDDP). Current understanding mechanisms driving CDDP resistance in SCLC is incomplete. Notably, Interferon inducible transmembrane protein1 (IFITM1) has been identified as key player distant metastasis SCLC. Analysis The Cancer Genome Atlas (TCGA) database revealed that IFITM1 expression markedly...

10.1016/j.heliyon.2024.e30806 article EN cc-by-nc-nd Heliyon 2024-05-01

Abstract The development of high‐energy and safe sodium metal batteries (SMBs) remains largely challenging due to the lack a viable electrolyte, especially at high rates temperatures. Here highly electrolyte is reported via engineering fluorinated solvents potassium trifluoro(2‐fluoropyridin‐3‐yl)borate (PTFB) additive for SMBs under extreme conditions. as‐formulated not only exhibits excellent Non‐flammability, heat resistance, anodic stability but also promotes formation NaF‐dominated...

10.1002/adfm.202423841 article EN Advanced Functional Materials 2025-01-23

With the explosive growth of 3D content creation, there is an increasing demand for automatically converting static models into articulation-ready versions that support realistic animation. Traditional approaches rely heavily on manual annotation, which both time-consuming and labor-intensive. Moreover, lack large-scale benchmarks has hindered development learning-based solutions. In this work, we present MagicArticulate, effective framework transforms assets. Our key contributions are...

10.48550/arxiv.2502.12135 preprint EN arXiv (Cornell University) 2025-02-17

Scope Given the d ‐lactate dehydrogenase (D‐LDH) deficiency, L‐ but not is assumed to be physiological isomer in mammals. Paradoxically, many fermented foods (e.g., yogurt, sauerkraut, cheeses) often contain substantial amounts of ‐lactate. In present study, dietary may a previously unrecognized nutrient aiding inflammatory resolution hypothesized. Methods and results The anti‐inflammatory properties are evaluated experimental colitis endotoxemia. Oral administration favorably affects acute...

10.1002/mnfr.202200196 article EN Molecular Nutrition & Food Research 2022-10-14
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