A5090574040- Acute Ischemic Stroke Management
- Sepsis Diagnosis and Treatment
- Antiplatelet Therapy and Cardiovascular Diseases
- Cancer-related molecular mechanisms research
- Traumatic Brain Injury and Neurovascular Disturbances
- Cancer-related gene regulation
- Coronary Interventions and Diagnostics
- Circular RNAs in diseases
- Stroke Rehabilitation and Recovery
- Lipoproteins and Cardiovascular Health
- Venous Thromboembolism Diagnosis and Management
- Acute Kidney Injury Research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- MicroRNA in disease regulation
- Single-cell and spatial transcriptomics
- Bariatric Surgery and Outcomes
- RNA modifications and cancer
- Peripheral Artery Disease Management
- Intracerebral and Subarachnoid Hemorrhage Research
- Cardiovascular Disease and Adiposity
- Intensive Care Unit Cognitive Disorders
- Neonatal and fetal brain pathology
- Cardiac Arrest and Resuscitation
- Cerebrovascular and Carotid Artery Diseases
- Cancer Genomics and Diagnostics
Affiliated Hospital of Hangzhou Normal University
2024-2025
Hangzhou Normal University
2023-2024
First Affiliated Hospital of Chengdu Medical College
2022-2024
Shanghai University of Traditional Chinese Medicine
2024
Seventh People's Hospital of Shanghai
2024
Shanghai East Hospital
2024
Shanghai University of Medicine and Health Sciences
2024
Tongji University
2024
Fudan University
2024
Treatment of acute stroke, before a distinction can be made between ischemic and hemorrhagic types, is challenging. Whether very early blood-pressure control in the ambulance improves outcomes among patients with undifferentiated stroke uncertain.
Background Ischemic stroke is a critical neurological condition, with infection representing significant aspect of its clinical management. Sepsis, life-threatening organ dysfunction resulting from infection, among the most dangerous complications in intensive care unit (ICU). Currently, no model exists to predict onset sepsis ischemic patients. This study aimed develop first predictive for patients using data MIMIC-IV database, leveraging machine learning techniques. Methods A total 2238...
Background: Increased postoperative glycemic variability (GV) has been shown to be associated with an increased risk for adverse outcomes. However, the impact of GV on long-term mortality after cardiac surgery, particularly regarding other interactive factors, remains unknown. In this study, we sought investigate whether is one-year mortality, and determine preoperative hemoglobin A1C (HbA1C) levels or diabetes status contribute GV-related following coronary artery bypass grafting (CABG)....
Objective Septic shock is a serious medical condition characterized by extreme inflammation and blood vessel permeability. Fluid resuscitation crucial treatment for septic shock, but the optimal approach fluid management remains controversial. In this study, we explored how perfusion index (PI) monitoring can help direct therapy shock. Methods Between January 2019 December 2021, 50 patients with were admitted to The Affiliated Hospital of Hangzhou Normal University randomly assigned either...
Background/aim We aimed to construct a validated nomogram model for predicting short-term (28-day) ischemic stroke mortality among critically ill populations. Materials and methods collected raw data from the Medical Information Mart Intensive Care IV database, comprehensive repository renowned its depth breadth in critical care information. Subsequently, rigorous analytical framework was employed, incorporating 10-fold cross-validation procedure ensure robustness reliability. Leveraging...
Abstract Extrachromosomal circular DNA (eccDNA) is a new biomarker and regulator of diseases. However, the role eccDNAs in large‐artery atherosclerotic (LAA) stroke remains unclear. Through high‐throughput circle‐sequencing technique, length distribution, genomic characteristic motifs feature plasma eccDNA from healthy controls (CON) patients with LAA were analysed. Then, potential functions annotated investigated using GO KEGG pathway analyses. EccDNAs mapped to reference genome showed SHN3...
N6-methyladenosine (m
It is significant to note that 50% of patients with sepsis show cardiac insufficiency. Ginsenoside-Rg1 (G-Rg1) has been shown have a cardiovascular protective effect. However, whether G-Rg1 involved in the mechanism action sepsis-induced myocardial damage (SIMD) unclear. This study aimed investigate effect on SIMD and further its mechanisms regulation downstream pathways. An vivo model was established mice by cecal ligation puncture (CLP), administered intraperitoneally 35 or 70 mg/kg after...
BackgroundLimited clinical prediction models exist to assess the likelihood of acute kidney injury (AKI) occurrence in ischemic stroke individuals. In this retrospective study, our aim was construct a nomogram that utilizes commonly available features predict AKI during intensive care unit hospitalization among patient population.MethodsIn MIMIC-IV database utilized investigate potential risk factors associated with incidence A predictive developed based on these identified factors. The...
Abstract Background: There has been limited evidence and inconsistent results on the safety effectiveness of prior antiplatelet (PA) use for acute ischemic stroke (AIS) patients treated with endovascular treatment (EVT). Methods: We prospectively enrolled consecutive from two comprehensive centers in China June 2015 to 2019. The efficacy outcomes were vascular recanalization rate, early neurological function improvement (24-hour NIHSS decreased ≥4), poor prognosis at 90 days (mRS 3-6), death...