Boxuan Pu

ORCID: 0009-0008-5323-3090
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About
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Research Areas
  • Heart Failure Treatment and Management
  • Cardiovascular Function and Risk Factors
  • Health disparities and outcomes
  • Acute Myocardial Infarction Research
  • Chronic Disease Management Strategies
  • Cardiac Fibrosis and Remodeling
  • Cardiac Health and Mental Health
  • Energy and Environment Impacts
  • Blood Pressure and Hypertension Studies
  • Global Health Care Issues
  • Air Quality and Health Impacts
  • Heavy Metal Exposure and Toxicity
  • Cardiac Structural Anomalies and Repair
  • Intensive Care Unit Cognitive Disorders
  • Climate Change and Health Impacts
  • Physical Activity and Health
  • Heavy metals in environment
  • Electrolyte and hormonal disorders
  • Cardiovascular Health and Risk Factors
  • Nutritional Studies and Diet
  • Chronic Kidney Disease and Diabetes
  • Stuttering Research and Treatment
  • Mitochondrial Function and Pathology
  • Aortic aneurysm repair treatments
  • Health and Lifestyle Studies

Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2025

Peking Union Medical College Hospital
2023

North China University of Science and Technology
2020

Abstract Objective This study examined the association between physical activity patterns and abdominal general adiposity. Methods Data were extracted among 20‐ to 59‐year‐old participants in National Health Nutrition Examination Survey (NHANES) from 2011 2018. Abdominal adiposity was assessed by dual‐energy x‐ray absorptiometry (DXA) anthropometric measures. DXA‐measured indicators further normalized into z scores. Physical levels collected questionnaire classified as inactive, “weekend...

10.1002/oby.23986 article EN cc-by-nc Obesity 2024-02-20

Poor cardiovascular-kidney-metabolic (CKM) health is associated with premature mortality and excess morbidity in the United States. Adverse social conditions have a prominent impact on cardiometabolic diseases during life course. We aim to examine association between risk profile (SRP) CKM multimorbidity among US adults.

10.1161/jaha.124.034996 article EN cc-by-nc-nd Journal of the American Heart Association 2024-08-13

The chronic effects of fine particulate matter (PM2.5) at high concentrations remains uncertain. We aimed to examine the relationship long-term PM2.5 exposure with all-cause and top three causes death (cardiovascular disease [CVD], cancer, respiratory disease), analyze their concentration-response functions over a wide range concentrations.We enrolled community residents aged 35-75 years from 2014 2017 all 31 provinces Chinese Mainland, followed them up until 2021. used estimation dataset...

10.1016/j.lanwpc.2023.100908 article EN cc-by-nc-nd The Lancet Regional Health - Western Pacific 2023-09-22

Abstract Aims There are limited tools to predict long‐term mortality among patients hospitalized with acute heart failure (AHF) in China. This study aimed develop and validate a model risk who were AHF discharged alive. Methods We used data from China Patient‐Centred Evaluative Assessment of Cardiac Events Prospective Heart Failure Study. Multivariate Cox proportional hazard was internal 4 year risk. Results The included 4875 for AHF, whom 2066 (42.38%) died within years following admission,...

10.1002/ehf2.15207 article EN cc-by-nc-nd ESC Heart Failure 2025-03-17

Background Elevated hsCRP (high-sensitivity C-reactive protein) level is associated with worse prognosis among patients hospitalized for heart failure. However, the prognostic value of long-term cumulative remains unknown. Methods and Results We consecutively enrolled failure collected their data at admission 1 12 months after discharge. Long-term was evaluated using 2 approaches, quartiles times high levels. Patients were classified into 4 groups by levels (0- to 3-times: number that higher...

10.1161/jaha.123.029386 article EN cc-by-nc-nd Journal of the American Heart Association 2023-09-30

Sparse data exist regarding how clinician-assigned New York Heart Association (NYHA) class compares with heart failure (HF)-specific Kansas City Cardiomyopathy Questionnaire (KCCQ) in acute HF.To compare concordance between NYHA and KCCQ overall summary score (KCCQ-OS) HF investigate associations of changes KCCQ-OS long-term outcomes.In this cohort study, patients were enrolled from 52 hospitals China August 2016 May 2018. Among at admission 1 month, levels each scale categorized into 4...

10.1001/jamanetworkopen.2023.39458 article EN cc-by-nc-nd JAMA Network Open 2023-10-24

Background The age-related trends in the predictive ability of carotid intima-media thickness (CIMT) for cardiovascular risk remain unclear. We aimed to identify value CIMT death. Methods and Results In a prospective cohort adults aged 35 75 years without history disease who were enrolled between 2014 2020, we measured at baseline collected vital status cause divided study population into 4 age groups (35-44, 45-54, 55-64, 65-75 years). Competing models fitted estimate associations added...

10.1161/jaha.123.029656 article EN cc-by-nc-nd Journal of the American Heart Association 2023-06-22

Abstract Aims This study aimed to evaluate the cumulative high‐sensitivity cardiac troponin T (hs‐cTNT) from admission 12 months after discharge and its association with mortality among patients acute heart failure (HF). Methods We used data China Patient‐Centered Evaluative Assessment of Cardiac Events Prospective Heart Failure Study (China PEACE 5p‐HF Study), which enrolled hospitalized primarily for HF 52 hospitals between 2016 2018. included who survived within had hs‐cTNT at (within 48...

10.1002/ehf2.14328 article EN cc-by-nc-nd ESC Heart Failure 2023-03-03

Inflammation contributes to the progression of heart failure (HF). However, long-term inflammatory trajectories and their associations with outcomes in patients acute HF remain unclear.

10.2147/jir.s387534 article EN cc-by-nc Journal of Inflammation Research 2023-01-01

Background: The American Heart Association recently updated the Cardiovascular Kidney Metabolic (CKM) Health advisory, proposing a new framework for defining, staging, and predicting CKM risk. However, prevalence adverse effects of stages remain insufficiently characterized. Methods: We analyzed data from National Nutrition Examination Survey (NHANES) (1999 to 2018), including 18,350 US adults aged 20 79 years. syndrome encompasses subclinical or clinical cardiovascular disease (CVD),...

10.1101/2024.12.19.24319121 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2024-12-20

To examine the association between cumulative cognitive function and subsequent mortality among patients hospitalized for acute heart failure (AHF). Based on a prospective cohort of AHF, was measured using Mini-Cog test at admission, 1- 12-month following discharge. Cumulative interpreted by score times impairment. Outcomes included all-cause cardiovascular mortality. 1 454 AHF with median follow-up 4.76 (interquartile range [IQR]: 4.18-5.07) years were included. Tertile had highest risk...

10.1093/gerona/glad288 article EN cc-by-nc-nd The Journals of Gerontology Series A 2024-01-03

Abstract Aims We aim to examine the association between long-term cumulative health status and subsequent mortality among patients with acute heart failure (HF). Methods results Based on a national prospective cohort study of hospitalized for HF, we measured by Kansas City Cardiomyopathy Questionnaire (KCCQ)-12 at four time points, i.e. admission 1, 6 12 months after discharge. Cumulative was interpreted KCCQ-12 score times good status. Outcomes included all-cause cardiovascular mortality....

10.1093/ehjqcco/qcae017 article EN European Heart Journal - Quality of Care and Clinical Outcomes 2024-03-06

Background: Patients with acute heart failure (HF) are at high risk of 30-day readmission. Little is known about the characteristics and associated factors readmissions among patients HF in China. Methods: We enrolled consecutive hospitalized for discharged from 52 hospitals China August 2016 to May 2018. describe rate readmission, time interval discharge causes also analyzed readmission by fitting multivariate Cox proportional hazards models. Results: included 4875 a median age 67 years...

10.31083/j.rcm2508279 article EN cc-by Reviews in Cardiovascular Medicine 2024-08-08

An association between increased aortic root dimensions (ARD) and elevated risk of cardiovascular mortality has been reported in the general population. However, evidence regarding ARD patients with acute heart failure (AHF) is limited.

10.1016/j.heliyon.2024.e37026 article EN cc-by-nc Heliyon 2024-08-28

Manganese (Mn) is a known toxicant and an essential trace element, it plays important role in various mechanisms relation to cardiovascular health. However, epidemiological studies of the association between blood Mn diseases (CVD) among U.S. adults are rare. A cross-sectional study 12,061 participants aged ≥ 20 was conducted using data from National Health Nutrition Examination Survey 2011–2018. Logistic regression restricted cubic spline were used examine relationship levels total CVD risk...

10.1038/s41598-024-82673-4 article EN cc-by-nc-nd Scientific Reports 2024-12-28

Background: The chronic effects of fine particulate matter (PM2.5) at high concentrations remains uncertain. We aimed to examine the relationship long-term PM2.5 exposure with all-cause and top three causes death (cardiovascular disease [CVD], cancer, respiratory disease), analyze their concentration-response functions over a wide range concentrations.Methods: enrolled community residents aged 35-75 years from 2014 2017 all 31 provinces Chinese Mainland, followed them up until 2021. used...

10.2139/ssrn.4494165 preprint EN 2023-01-01
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