A5080318790- Heart Failure Treatment and Management
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Mobile Health and mHealth Applications
- Cardiovascular Health and Risk Factors
- Chronic Disease Management Strategies
- Cardiac Health and Mental Health
- Health Systems, Economic Evaluations, Quality of Life
- Meta-analysis and systematic reviews
- Cardiac Fibrosis and Remodeling
- Cardiac Arrest and Resuscitation
- Digital Mental Health Interventions
- Cardiac Imaging and Diagnostics
- Artificial Intelligence in Healthcare
- Diabetes Management and Research
- Bone health and osteoporosis research
- Diabetes Management and Education
- Healthcare Systems and Public Health
- Cardiac Structural Anomalies and Repair
- Cardiac, Anesthesia and Surgical Outcomes
- Health, Technology, Consumer Behavior
- Diabetes Treatment and Management
- Blood Pressure and Hypertension Studies
- Lipoproteins and Cardiovascular Health
- Health Literacy and Information Accessibility
Chinese Academy of Medical Sciences & Peking Union Medical College
2017-2025
University of Oxford
2020-2023
National Clinical Research
2019-2021
Peking Union Medical College Hospital
2021
Fu Wai Hospital
2018-2020
New York Academy of Medicine
2019
Background: Mobile health interventions may support risk factor management and are readily scalable in healthcare systems. We aim to evaluate the efficacy of a text messaging–based intervention improve glycemic control patients with coronary heart disease diabetes mellitus China. Methods Results: The CHAT-DM study (Cardiovascular Health Texting-Diabetes Mellitus) was parallel-group, single-blind, randomized clinical trial that included 502 both from 34 hospitals group (n=251) received 6...
Background: Mobile health technologies are low cost, scalable interventions with the potential to promote patient engagement and behavior change. We aimed test whether a culturally sensitive text messaging intervention supporting secondary prevention improves control of risk factors in patients coronary heart disease China. Methods Results: In this multicenter, single-blinded randomized controlled trial, 822 (mean age, 56.4 [SD, 9.5] years; 14.1% women) without diabetes mellitus from 37...
Abstract Aims There are limited tools to predict long‐term mortality among patients hospitalized with acute heart failure (AHF) in China. This study aimed develop and validate a model risk who were AHF discharged alive. Methods We used data from China Patient‐Centred Evaluative Assessment of Cardiac Events Prospective Heart Failure Study. Multivariate Cox proportional hazard was internal 4 year risk. Results The included 4875 for AHF, whom 2066 (42.38%) died within years following admission,...
Background Elevated hsCRP (high-sensitivity C-reactive protein) level is associated with worse prognosis among patients hospitalized for heart failure. However, the prognostic value of long-term cumulative remains unknown. Methods and Results We consecutively enrolled failure collected their data at admission 1 12 months after discharge. Long-term was evaluated using 2 approaches, quartiles times high levels. Patients were classified into 4 groups by levels (0- to 3-times: number that higher...
Objective To assess the association between educational attainment and acute myocardial infarction (AMI) outcomes in China to inform future healthcare interventions. Methods We used data from Patient-centred Evaluative Assessment of Cardiac Events-Prospective AMI study 3369 consecutive patients hospitalised with 53 hospitals. Educational was categorised as: high (senior school, college or postgraduate degree), intermediate (junior school) low (primary school illiterate). survival models...
Vitamin D supplements may only be beneficial for the prevention of osteoporotic fractures when administered with calcium and in individuals low blood levels 25(OH)D, but possible hazards on CVD cannot excluded.
Sparse data exist regarding how clinician-assigned New York Heart Association (NYHA) class compares with heart failure (HF)-specific Kansas City Cardiomyopathy Questionnaire (KCCQ) in acute HF.To compare concordance between NYHA and KCCQ overall summary score (KCCQ-OS) HF investigate associations of changes KCCQ-OS long-term outcomes.In this cohort study, patients were enrolled from 52 hospitals China August 2016 May 2018. Among at admission 1 month, levels each scale categorized into 4...
Hypertension management in China is suboptimal with high prevalence and low control rate due to various barriers, including lack of self-management awareness patients inadequate capacity physicians. Digital therapeutic interventions mobile health computational device algorithms such as clinical decision support systems (CDSS) are scalable the potential improve blood pressure (BP) strengthen healthcare system resource-constrained areas, yet their effectiveness remains be tested. The aim this...
Introduction Mobile health interventions have the potential to promote risk factor management and lifestyle modification, are a particularly attractive approach for scaling across healthcare systems with limited resources. We conducting two randomised trials evaluate efficacy of text message-based messages in improving secondary coronary heart disease (CHD) prevention among patients or without diabetes. Methods analysis The Cardiovascular Health And Text Messaging (CHAT) Study CHAT-Diabetes...
Background Improving health status is one of the major goals in management heart failure (HF). However, little known about long-term individual trajectories patients with acute HF after discharge. Methods and Results We enrolled 2328 hospitalized for from 51 hospitals prospectively measured their via Kansas City Cardiomyopathy Questionnaire-12 at admission 1, 6, 12 months discharge, respectively. The median age included was 66 years, 63.3% were men. Six patterns identified by a latent class...
Abstract Aims This study aimed to evaluate the cumulative high‐sensitivity cardiac troponin T (hs‐cTNT) from admission 12 months after discharge and its association with mortality among patients acute heart failure (HF). Methods We used data China Patient‐Centered Evaluative Assessment of Cardiac Events Prospective Heart Failure Study (China PEACE 5p‐HF Study), which enrolled hospitalized primarily for HF 52 hospitals between 2016 2018. included who survived within had hs‐cTNT at (within 48...
Inflammation contributes to the progression of heart failure (HF). However, long-term inflammatory trajectories and their associations with outcomes in patients acute HF remain unclear.
Patients admitted to hospital with acute myocardial infarction (AMI) have considerable variability in in-hospital risks, resulting higher demands on healthcare resources. Simple risk-assessment tools are important for the identification of patients risk inform clinical decisions. However, few assessment been built that suitable populations AMI China. We aim develop and validate a prediction model, further build scoring system.Data from nationally representative retrospective study was used...
Abstract Aims We aim to examine the association between long-term cumulative health status and subsequent mortality among patients with acute heart failure (HF). Methods results Based on a national prospective cohort study of hospitalized for HF, we measured by Kansas City Cardiomyopathy Questionnaire (KCCQ)-12 at four time points, i.e. admission 1, 6 12 months after discharge. Cumulative was interpreted KCCQ-12 score times good status. Outcomes included all-cause cardiovascular mortality....
Background: Mobile health technologies are low-cost, scalable interventions with the potential to promote patient engagement and behavior change. We designed tested a tailored culturally-sensitive text messaging intervention support secondary prevention in patients coronary heart disease. Methods: In this multi-center, single-blinded randomized controlled trial, we enrolled 822 (mean age, 56.4 [SD, 9.5] years; 16.1% [132 of 822] women) history AMI or PCI without diabetes from 37 hospitals...
Individual non-cardiac comorbidities are prevalent in HF; however, few studies reported how the aggregate burden of affects long-term outcomes, and it is unknown whether this associated with changes health status.To assess association overall clinical outcomes quality life (QoL) patients hospitalized for heart failure (HF).We prospectively enrolled HF from 52 hospitals China. Eight key [diabetes, chronic renal disease, obstructive pulmonary disease (COPD), anemia, stroke, cancer, peripheral...
Background: China has a growing burden of acute myocardial infarction (AMI) and wide variation in educational attainment. Less education is associated with worse cardiovascular outcomes Western populations; whether this relationship exists unclear. We assessed the association between attainment AMI to inform future healthcare interventions. Methods: used data from prospective PEACE-Prospective study 3369 consecutive patients hospitalized 53 hospitals across all 21 provinces 2012 2015....
目的 中国是人口多样化、教育程度差异很大的国家，然而教育程度与我国急性心肌梗死（AMI）患者预后的相关性仍不清楚。本研究旨在探索AMI患者的教育程度与预后的相关性，以期进一步指导未来健康医疗干预的方向。 方法 研究基于China PEACE前瞻性AMI研究的数据，共纳入来自中国53家医院的3 369名连续入选的AMI患者，并根据其接受教育的程度分为高（高中、大学及研究生）、中（初中学位）、低（小学及小学以下）3个不同水平。采用生存模型分析不同教育程度与AMI后1年严重心血管病不良事件（MACE）发生率和全因病死率的关系，并校正了人口统计学和心血管危险因素等差异的影响。 结果 研究人群的中位年龄为61（52~69）岁，23.2%为女性，33.3%为高学历水平，32.4%为中等学历水平，34.3%为低学历水平。与高中、大学或研究生学历相比，小学或小学以下学历患者的1年MACE发生率更高(危害比2.41, 95%可信区间1.72~3.37)，全因病死率也显著增高(危害比3.09,...